Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13

por Yang, Jianzhang, Chang, Yu, Tien, Jean Ching-Yi, Wang, Zhen, Zhou, Yang, Zhang, Pujuan, Huang, Weixue, Vo, Josh, Apel, Ingrid J., Wang, Cynthia, Zeng, Victoria Zhixuan, Cheng, Yunhui, Li, Shuqin, Wang, George Xiaoju, Chinnaiyan, Arul M., Ding, Ke
Publicado 2022

The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma

por Vo, Josh N., Wu, Yi-Mi, Mishler, Jeanmarie, Hall, Sarah, Mannan, Rahul, Wang, Lisha, Ning, Yu, Zhou, Jin, Hopkins, Alexander C., Estill, James C., Chan, Wallace K. B., Yesil, Jennifer, Cao, Xuhong, Rao, Arvind, Tsodikov, Alexander, Talpaz, Moshe, Cole, Craig E., Ye, Jing C., Bergsagel, P. Leif, Auclair, Daniel, Cho, Hearn Jay, Robinson, Dan R., Chinnaiyan, Arul M.
Publicado 2022

Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations

por Roberts, Holly J., Ji, Sunjong, Picca, Alberto, Sanson, Marc, Garcia, Mekka, Snuderl, Matija, Schüller, Ulrich, Picart, Thiébaud, Ducray, François, Green, Adam L., Nakano, Yoshiko, Sturm, Dominik, Abdullaev, Zied, Aldape, Kenneth, Dang, Derek, Kumar-Sinha, Chandan, Wu, Yi-Mi, Robinson, Dan, Vo, Josh N., Chinnaiyan, Arul M., Cartaxo, Rodrigo, Upadhyaya, Santhosh A., Mody, Rajen, Chiang, Jason, Baker, Suzanne, Solomon, David, Venneti, Sriram, Pratt, Drew, Waszak, Sebastian M., Koschmann, Carl
Publicado 2023

Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer

por Qiao, Yuanyuan, Choi, Jae Eun, Tien, Jean C., Simko, Stephanie A., Rajendiran, Thekkelnaycke, Vo, Josh N., Delekta, Andrew D., Wang, Lisha, Xiao, Lanbo, Hodge, Nathan B., Desai, Parth, Mendoza, Sergio, Juckette, Kristin, Xu, Alice, Soni, Tanu, Su, Fengyun, Wang, Rui, Cao, Xuhong, Yu, Jiali, Kryczek, Ilona, Wang, Xiao-Ming, Wang, Xiaoju, Siddiqui, Javed, Wang, Zhen, Bernard, Amélie, Fernandez-Salas, Ester, Navone, Nora M., Ellison, Stephanie J., Ding, Ke, Eskelinen, Eeva-Liisa, Heath, Elisabeth I., Klionsky, Daniel J., Zou, Weiping, Chinnaiyan, Arul M.
Publicado 2021

Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

por Xiao, Lanbo, Parolia, Abhijit, Qiao, Yuanyuan, Bawa, Pushpinder, Eyunni, Sanjana, Mannan, Rahul, Carson, Sandra E., Chang, Yu, Wang, Xiaoju, Zhang, Yuping, Vo, Josh N., Kregel, Steven, Simko, Stephanie A., Delekta, Andrew D., Jaber, Mustapha, Zheng, Heng, Apel, Ingrid J., McMurry, Lisa, Su, Fengyun, Wang, Rui, Zelenka-Wang, Sylvia, Sasmal, Sanjita, Khare, Leena, Mukherjee, Subhendu, Abbineni, Chandrasekhar, Aithal, Kiran, Bhakta, Mital S., Ghurye, Jay, Cao, Xuhong, Navone, Nora M., Nesvizhskii, Alexey I., Mehra, Rohit, Vaishampayan, Ulka, Blanchette, Marco, Wang, Yuzhuo, Samajdar, Susanta, Ramachandra, Murali, Chinnaiyan, Arul M.
Publicado 2021