Clustering gene expression time series data using an infinite Gaussian process mixture model

por McDowell, Ian C., Manandhar, Dinesh, Vockley, Christopher M., Schmid, Amy K., Reddy, Timothy E., Engelhardt, Barbara E.
Publicado 2018

Genome-wide quantification of the effects of DNA methylation on human gene regulation

por Lea, Amanda J, Vockley, Christopher M, Johnston, Rachel A, Del Carpio, Christina A, Barreiro, Luis B, Reddy, Timothy E, Tung, Jenny
Publicado 2018

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers

por Hilton, Isaac B., D’Ippolito, Anthony M., Vockley, Christopher M., Thakore, Pratiksha I., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

por Vockley, Christopher M., Guo, Cong, Majoros, William H., Nodzenski, Michael, Scholtens, Denise M., Hayes, M. Geoffrey, Lowe, William L., Reddy, Timothy E.
Publicado 2015

Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain

por Kabadi, Ami M., Thakore, Pratiksha I., Vockley, Christopher M., Ousterout, David G., Gibson, Tyler M., Guilak, Farshid, Reddy, Timothy E., Gersbach, Charles A.
Publicado 2014

Human genome-wide measurement of drug-responsive regulatory activity

por Johnson, Graham D., Barrera, Alejandro, McDowell, Ian C., D’Ippolito, Anthony M., Majoros, William H., Vockley, Christopher M., Wang, Xingyan, Allen, Andrew S., Reddy, Timothy E.
Publicado 2018

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

por Polstein, Lauren R., Perez-Pinera, Pablo, Kocak, D. Dewran, Vockley, Christopher M., Bledsoe, Peggy, Song, Lingyun, Safi, Alexias, Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

por Frank, Christopher L., Liu, Fang, Wijayatunge, Ranjula, Song, Lingyun, Biegler, Matthew T., Yang, Marty G., Vockley, Christopher M., Safi, Alexias, Gersbach, Charles A., Crawford, Gregory E., West, Anne E.
Publicado 2015

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

por Perez-Pinera, Pablo, Kocak, D. Dewran, Vockley, Christopher M., Adler, Andrew F., Kabadi, Ami M., Polstein, Lauren R., Thakore, Pratiksha I., Glass, Katherine A., Ousterout, David G., Leong, Kam W., Guilak, Farshid, Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2013

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

por McDowell, Ian C., Barrera, Alejandro, D'Ippolito, Anthony M., Vockley, Christopher M., Hong, Linda K., Leichter, Sarah M., Bartelt, Luke C., Majoros, William H., Song, Lingyun, Safi, Alexias, Koçak, D. Dewran, Gersbach, Charles A., Hartemink, Alexander J., Crawford, Gregory E., Engelhardt, Barbara E., Reddy, Timothy E.
Publicado 2018