Development of the first geldanamycin-based HSP90 degraders

por Wurnig, Silas, Vogt, Melina, Hogenkamp, Julian, Dienstbier, Niklas, Borkhardt, Arndt, Bhatia, Sanil, Hansen, Finn K.
Publicado 2023

A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2

por Palei, Shubhendu, Weisner, Jörn, Vogt, Melina, Gontla, Rajesh, Buchmuller, Benjamin, Ehrt, Christiane, Grabe, Tobias, Kleinbölting, Silke, Müller, Matthias, Clever, Guido H., Rauh, Daniel, Summerer, Daniel
Publicado 2022

Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors

por Stachura, Paweł, Liu, Wei, Xu, Haifeng C., Wlodarczyk, Agnès, Stencel, Olivia, Pandey, Piyush, Vogt, Melina, Bhatia, Sanil, Picard, Daniel, Remke, Marc, Lang, Karl S., Häussinger, Dieter, Homey, Bernhard, Lang, Philipp A., Borkhardt, Arndt, Pandyra, Aleksandra A.
Publicado 2023

Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization

por Bhatia, Sanil, Spanier, Lukas, Bickel, David, Dienstbier, Niklas, Woloschin, Vitalij, Vogt, Melina, Pols, Henrik, Lungerich, Beate, Reiners, Jens, Aghaallaei, Narges, Diedrich, Daniela, Frieg, Benedikt, Schliehe-Diecks, Julian, Bopp, Bertan, Lang, Franziska, Gopalswamy, Mohanraj, Loschwitz, Jennifer, Bajohgli, Baubak, Skokowa, Julia, Borkhardt, Arndt, Hauer, Julia, Hansen, Finn K., Smits, Sander H. J., Jose, Joachim, Gohlke, Holger, Kurz, Thomas
Publicado 2022