Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells

por Pérez-Rodriguez, Saumel, Wulff, Tune, Voldborg, Bjørn G., Altamirano, Claudia, Trujillo-Roldán, Mauricio A., Valdez-Cruz, Norma A.
Publicado 2021

Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter

por Dahodwala, Hussain, Kaushik, Prashant, Tejwani, Vijay, Kuo, Chih-Chung, Menard, Patrice, Henry, Michael, Voldborg, Bjorn G., Lewis, Nathan E., Meleady, Paula, Sharfstein, Susan T.
Publicado 2019

CHOmics: A web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines

por Lin, Dongdong, Yalamanchili, Hima B., Zhang, Xinmin, Lewis, Nathan E., Alves, Christina S., Groot, Joost, Arnsdorf, Johnny, Bjørn, Sara P., Wulff, Tune, Voldborg, Bjørn G., Zhou, Yizhou, Zhang, Baohong
Publicado 2020

Inferring secretory and metabolic pathway activity from omic data with secCellFie

por Masson, Helen O., Samoudi, Mojtaba, Robinson, Caressa M., Kuo, Chih-Chung, Weiss, Linus, Doha, Km Shams Ud, Campos, Alex, Tejwani, Vijay, Dahodwala, Hussain, Menard, Patrice, Voldborg, Bjorn G., Sharfstein, Susan T., Lewis, Nathan E.
Publicado 2023

Combating viral contaminants in CHO cells by engineering innate immunity

por Chiang, Austin W. T., Li, Shangzhong, Kellman, Benjamin P., Chattopadhyay, Gouri, Zhang, Yaqin, Kuo, Chih-Chung, Gutierrez, Jahir M., Ghazi, Faezeh, Schmeisser, Hana, Ménard, Patrice, Bjørn, Sara Petersen, Voldborg, Bjørn G., Rosenberg, Amy S., Puig, Montserrat, Lewis, Nathan E.
Publicado 2019

Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

por Tulika, Tulika, Pedersen, Rasmus W., Rimbault, Charlotte, Ahmadi, Shirin, Rivera‐de‐Torre, Esperanza, Fernández‐Quintero, Monica L., Loeffler, Johannes R., Bohn, Markus‐Frederik, Ljungars, Anne, Ledsgaard, Line, Voldborg, Bjørn G., Ruso‐Julve, Fulgencio, Andersen, Jan Terje, Laustsen, Andreas H.
Publicado 2023

Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion

por van Wijk, Xander M., Döhrmann, Simon, Hallström, Björn M., Li, Shangzhong, Voldborg, Bjørn G., Meng, Brandon X., McKee, Karen K., van Kuppevelt, Toin H., Yurchenco, Peter D., Palsson, Bernhard O., Lewis, Nathan E., Nizet, Victor, Esko, Jeffrey D.
Publicado 2017

Multiplex secretome engineering enhances recombinant protein production and purity

por Kol, Stefan, Ley, Daniel, Wulff, Tune, Decker, Marianne, Arnsdorf, Johnny, Schoffelen, Sanne, Hansen, Anders Holmgaard, Jensen, Tanja Lyholm, Gutierrez, Jahir M., Chiang, Austin W. T., Masson, Helen O., Palsson, Bernhard O., Voldborg, Bjørn G., Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Lee, Gyun Min, Lewis, Nathan E.
Publicado 2020