Strongly Truncated Dnaaf4 Plays a Conserved Role in Drosophila Ciliary Dynein Assembly as Part of an R2TP-Like Co-Chaperone Complex With Dnaaf6

por Lennon, Jennifer, zur Lage, Petra, von Kriegsheim, Alex, Jarman, Andrew P.
Publicado 2022

H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci

por Sundarraj, Jayakumar, Taylor, Gillian C.A., von Kriegsheim, Alex, Pradeepa, Madapura M
Publicado 2021

Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib

por Nolan, Aoife, Raso, Cinzia, Kolch, Walter, von Kriegsheim, Alex, Wynne, Kieran, Matallanas, David
Publicado 2023

Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols

por Schildknecht, Stefan, von Kriegsheim, Alex, Vujacic-Mirski, Ksenija, Di Lisa, Fabio, Ullrich, Volker, Daiber, Andreas
Publicado 2022

Signalling mechanisms regulating phenotypic changes in breast cancer cells

por Volinsky, Natalia, McCarthy, Cormac J., von Kriegsheim, Alex, Saban, Nina, Okada-Hatakeyama, Mariko, Kolch, Walter, Kholodenko, Boris N.
Publicado 2015

Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP

por zur Lage, Petra, Stefanopoulou, Panagiota, Styczynska-Soczka, Katarzyna, Quinn, Niall, Mali, Girish, von Kriegsheim, Alex, Mill, Pleasantine, Jarman, Andrew P.
Publicado 2018

The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly

por zur Lage, Petra, Xi, Zhiyan, Lennon, Jennifer, Hunter, Iain, Chan, Wai Kit, Bolado Carrancio, Alfonso, von Kriegsheim, Alex, Jarman, Andrew P.
Publicado 2021

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

por Smith, Matthew D., Harley, Margaret E., Kemp, Alain J., Wills, Jimi, Lee, Martin, Arends, Mark, von Kriegsheim, Alex, Behrends, Christian, Wilkinson, Simon
Publicado 2018

Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons

por Macdonald, Lewis, Taylor, Gillian C, Brisbane, Jennifer Margaret, Christodoulou, Ersi, Scott, Lucy, von Kriegsheim, Alex, Rossant, Janet, Gu, Bin, Wood, Andrew J
Publicado 2022

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

por Rodriguez, Javier, Pilkington, Ruth, Garcia Munoz, Amaya, Nguyen, Lan K., Rauch, Nora, Kennedy, Susan, Monsefi, Naser, Herrero, Ana, Taylor, Cormac T., von Kriegsheim, Alex
Publicado 2016

Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration

por Bolado-Carrancio, Alfonso, Rukhlenko, Oleksii S, Nikonova, Elena, Tsyganov, Mikhail A, Wheeler, Anne, Garcia-Munoz, Amaya, Kolch, Walter, von Kriegsheim, Alex, Kholodenko, Boris N
Publicado 2020

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359

por Rodriguez, Javier, Herrero, Ana, Li, Shuijie, Rauch, Nora, Quintanilla, Andrea, Wynne, Kieran, Krstic, Aleksandar, Acosta, Juan Carlos, Taylor, Cormac, Schlisio, Susanne, von Kriegsheim, Alex
Publicado 2018

Identification of a novel TIF-IA–NF-κB nucleolar stress response pathway

por Chen, Jingyu, Lobb, Ian T, Morin, Pierre, Novo, Sonia M, Simpson, James, Kennerknecht, Kathrin, von Kriegsheim, Alex, Batchelor, Emily E, Oakley, Fiona, Stark, Lesley A
Publicado 2018

A Novel C1q Domain-Containing Protein Isolated from the Mollusk Modiolus kurilensis Recognizing Glycans Enriched with Acidic Galactans and Mannans

por Grinchenko, Andrei V., von Kriegsheim, Alex, Shved, Nikita A., Egorova, Anna E., Ilyaskina, Diana V., Karp, Tatiana D., Goncharov, Nikolay V., Petrova, Irina Y., Kumeiko, Vadim V.
Publicado 2021

Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

por Titmarsh, Helen F., von Kriegsheim, Alex, Wills, Jimi C., O’Connor, Richard A., Dhaliwal, Kevin, Frame, Margaret C., Pattle, Samuel B., Dorward, David A., Byron, Adam, Akram, Ahsan R.
Publicado 2023

Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE

por Cavadas, Miguel, Oikonomidi, Ioanna, Gaspar, Catarina J., Burbridge, Emma, Badenes, Marina, Félix, Inês, Bolado, Alfonso, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Domingos, Pedro M., von Kriegsheim, Alex, Adrain, Colin
Publicado 2017

Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function

por Haward, Fiona, Maslon, Magdalena M, Yeyati, Patricia L, Bellora, Nicolas, Hansen, Jan N, Aitken, Stuart, Lawson, Jennifer, von Kriegsheim, Alex, Wachten, Dagmar, Mill, Pleasantine, Adams, Ian R, Caceres, Javier F
Publicado 2021

A novel role of MNT as a negative regulator of REL and the NF-κB pathway

por Liaño-Pons, Judit, Lafita-Navarro, M. Carmen, García-Gaipo, Lorena, Colomer, Carlota, Rodríguez, Javier, von Kriegsheim, Alex, Hurlin, Peter J., Ourique, Fabiana, Delgado, M. Dolores, Bigas, Anna, Espinosa, Lluis, León, Javier
Publicado 2021

Correction: A novel role of MNT as a negative regulator of REL and the NF-κB pathway

por Liaño-Pons, Judit, Lafita-Navarro, M. Carmen, García-Gaipo, Lorena, Colomer, Carlota, Rodríguez, Javier, von Kriegsheim, Alex, Hurlin, Peter J., Ourique, Fabiana, Delgado, M. Dolores, Bigas, Anna, Espinosa, Lluis, León, Javier
Publicado 2021

ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling

por Bolado-Carrancio, Alfonso, Lee, Martin, Ewing, Ailith, Muir, Morwenna, Macleod, Kenneth G., Gallagher, William M., Nguyen, Lan K., Carragher, Neil O., Semple, Colin A., Brunton, Valerie G., Caswell, Patrick T., von Kriegsheim, Alex
Publicado 2021