Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins

por Sinegubova, Maria V., Orlova, Nadezhda A., Vorobiev, Ivan I.
Publicado 2023

A modular assembly cloning technique (aided by the BIOF software tool) for seamless and error-free assembly of long DNA fragments

por Orlova, Nadezhda A, Orlov, Alexandre V, Vorobiev, Ivan I
Publicado 2012

Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based system

por Orlova, Nadezhda A., Kovnir, Sergey V., Gabibov, Alexandre G., Vorobiev, Ivan I.
Publicado 2017

Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur(®)) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency

por Sinegubova, Maria, Vorobiev, Ivan, Klishin, Anatoly, Eremin, Dmitry, Orlova, Nadezhda, Orlova, Natalya, Polzikov, Mikhail
Publicado 2022

High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector

por Sinegubova, Maria V., Orlova, Nadezhda A., Kovnir, Sergey V., Dayanova, Lutsia K., Vorobiev, Ivan I.
Publicado 2021

Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture

por Kolesov, Denis E., Sinegubova, Maria V., Safenkova, Irina V., Vorobiev, Ivan I., Orlova, Nadezhda A.
Publicado 2022

Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells

por Orlova, Nadezhda A, Kovnir, Sergey V, Hodak, Julia A, Vorobiev, Ivan I, Gabibov, Alexandre G, Skryabin, Konstantin G
Publicado 2014

Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD

por Kolesov, Denis E., Sinegubova, Maria V., Dayanova, Lutsia K., Dolzhikova, Inna V., Vorobiev, Ivan I., Orlova, Nadezhda A.
Publicado 2022

High-Level Production of Soluble Cross-Reacting Material 197 in Escherichia coli Cytoplasm Due to Fine Tuning of the Target Gene’s mRNA Structure

por Khodak, Yulia Alexandrovna, Ryazanova, Alexandra Yurievna, Vorobiev, Ivan Ivanovich, Kovalchuk, Alexander Leonidovich, Ovechko, Nikolay Nikolaevich, Aparin, Petr Gennadievich
Publicado 2023

Humoral Immune Responses in Patients with Severe COVID-19: A Comparative Pilot Study between Individuals Infected by SARS-CoV-2 during the Wild-Type and the Delta Periods

por Sukhova, Maria, Byazrova, Maria, Mikhailov, Artem, Yusubalieva, Gaukhar, Maslova, Irina, Belovezhets, Tatyana, Chikaev, Nikolay, Vorobiev, Ivan, Baklaushev, Vladimir, Filatov, Alexander
Publicado 2023

High-level expression of biologically active human follicle stimulating hormone in the Chinese hamster ovary cell line by a pair of tricistronic and monocistronic vectors

por Orlova, Nadezhda A., Kovnir, Sergey V., Khodak, Yulia A., Polzikov, Mikhail A., Nikitina, Victoria A., Skryabin, Konstantin G., Vorobiev, Ivan I.
Publicado 2019

New Infestin-4 Mutants with Increased Selectivity against Factor XIIa

por Kolyadko, Vladimir N., Lushchekina, Sofya V., Vuimo, Tatiana A., Surov, Stepan S., Ovsepyan, Ruzanna A., Korneeva, Vera A., Vorobiev, Ivan I., Orlova, Nadezhda A., Minakhin, Leonid, Kuznedelov, Konstantin, Severinov, Konstantin V., Ataullakhanov, Fazoil I., Panteleev, Mikhail A.
Publicado 2015