Interpretation of metabolic memory phenomenon using a physiological systems model: What drives oxidative stress following glucose normalization?

por Voronova, Veronika, Zhudenkov, Kirill, Helmlinger, Gabriel, Peskov, Kirill
Publicado 2017

Quantification of Scheduling Impact on Safety and Efficacy Outcomes of Brain Metastasis Radio- and Immuno-Therapies: A Systematic Review and Meta-Analysis

por Voronova, Veronika, Lebedeva, Svetlana, Sekacheva, Marina, Helmlinger, Gabriel, Peskov, Kirill
Publicado 2020

Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology

por Peskov, Kirill, Azarov, Ivan, Chu, Lulu, Voronova, Veronika, Kosinsky, Yuri, Helmlinger, Gabriel
Publicado 2019

Combination of immune checkpoint inhibitors with radiation therapy in cancer: A hammer breaking the wall of resistance

por Voronova, Veronika, Vislobokova, Anastasia, Mutig, Kerim, Samsonov, Mikhail, Peskov, Kirill, Sekacheva, Marina, Materenchuk, Maria, Bunyatyan, Natalya, Lebedeva, Svetlana
Publicado 2022

A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings

por Voronova, Veronika, Sokolov, Victor, Al-Khaifi, Amani, Straniero, Sara, Kumar, Chanchal, Peskov, Kirill, Helmlinger, Gabriel, Rudling, Mats, Angelin, Bo
Publicado 2020

Concentration‐QT modelling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations

por Voronova, Veronika, Cullberg, Marie, Delff, Philip, Parkinson, Joanna, Dota, Corina, Schiavon, Gaia, Maroj, Brijesh, Rekić, Dinko, Cheung, S. Y. Amy
Publicado 2021

Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

por Kosinsky, Yuri, Dovedi, Simon J., Peskov, Kirill, Voronova, Veronika, Chu, Lulu, Tomkinson, Helen, Al-Huniti, Nidal, Stanski, Donald R., Helmlinger, Gabriel
Publicado 2018

Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model

por Voronova, Veronika, Sokolov, Victor, Morias, Yannick, Boezelman, Malin Jonsson, Wågberg, Maria, Henricsson, Marcus, Hansson, Karl, Goltsov, Alexey, Peskov, Kirill, Sundqvist, Monika
Publicado 2022

Diagnostic Value of Combinatorial Markers in Colorectal Carcinoma

por Voronova, Veronika, Glybochko, Peter, Svistunov, Andrey, Fomin, Viktor, Kopylov, Philipp, Tzarkov, Peter, Egorov, Alexey, Gitel, Evgenij, Ragimov, Aligeydar, Boroda, Alexander, Poddubskaya, Elena, Sekacheva, Marina
Publicado 2020

Evaluation of Combination Strategies for the A(2A)R Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model

por Voronova, Veronika, Peskov, Kirill, Kosinsky, Yuri, Helmlinger, Gabriel, Chu, Lulu, Borodovsky, Alexandra, Woessner, Richard, Sachsenmeier, Kris, Shao, Wenlin, Kumar, Rakesh, Pouliot, Gayle, Merchant, Melinda, Kimko, Holly, Mugundu, Ganesh
Publicado 2021

Quantitative Systems Pharmacology: An Exemplar Model‐Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development

por Helmlinger, Gabriel, Sokolov, Victor, Peskov, Kirill, Hallow, Karen M., Kosinsky, Yuri, Voronova, Veronika, Chu, Lulu, Yakovleva, Tatiana, Azarov, Ivan, Kaschek, Daniel, Dolgun, Artem, Schmidt, Henning, Boulton, David W., Penland, Robert C.
Publicado 2019