Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

por Ortega Ugalde, Sandra, Boot, Maikel, Commandeur, Jan N. M., Jennings, Paul, Bitter, Wilbert, Vos, J. Chris
Publicado 2019

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

por Huseinovic, Angelina, Dekker, Stefan J., Boogaard, Bob, Vermeulen, Nico. P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2018

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

por Huseinovic, Angelina, van Leeuwen, Jolanda S., van Welsem, Tibor, Stulemeijer, Iris, van Leeuwen, Fred, Vermeulen, Nico P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2017

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

por Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
Publicado 2018

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

por den Braver-Sewradj, Shalenie P., den Braver, Michiel W., Toorneman, Robin M., van Leeuwen, Stephanie, Zhang, Yongjie, Dekker, Stefan J., Vermeulen, Nico P. E., Commandeur, Jan N. M., Vos, J. Chris
Publicado 2017