Irreversible Antagonists for the Adenosine A(2B) Receptor †

por Temirak, Ahmed, Schlegel, Jonathan G., Voss, Jan H., Vaaßen, Victoria J., Vielmuth, Christin, Claff, Tobias, Müller, Christa E.
Publicado 2022

Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A(2A) Receptor with Preladenant Conjugates

por Claff, Tobias, Klapschinski, Tim A., Tiruttani Subhramanyam, Udaya K., Vaaßen, Victoria J., Schlegel, Jonathan G., Vielmuth, Christin, Voß, Jan H., Labahn, Jörg, Müller, Christa E.
Publicado 2022

Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα(q) Protein Inhibitors in Biological Samples

por Kuschak, Markus, Schlegel, Jonathan G., Schneider, Marion, Kehraus, Stefan, Voss, Jan H., Seidinger, Alexander, Matthey, Michaela, Wenzel, Daniela, Fleischmann, Bernd K., König, Gabriele M., Müller, Christa E.
Publicado 2020

Crystal structure of adenosine A(2A) receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction

por Claff, Tobias, Schlegel, Jonathan G., Voss, Jan H., Vaaßen, Victoria J., Weiße, Renato H., Cheng, Robert K. Y., Markovic-Mueller, Sandra, Bucher, Denis, Sträter, Norbert, Müller, Christa E.
Publicado 2023

Imaging of Gα(q) Proteins in Mouse and Human Organs and Tissues

por Voss, Jan H., Al-Hroub, Haneen, Gedschold, Robin, Dietrich, Jennifer M., Gaffal, Evelyn, Toma, Marieta, Kehraus, Stefan, König, Gabriele M., Brust, Peter, Fleischmann, Bernd K., Wenzel, Daniela, Deuther-Conrad, Winnie, Müller, Christa E.
Publicado 2022

Cell‐permeable high‐affinity tracers for G(q) proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors

por Kuschak, Markus, Namasivayam, Vigneshwaran, Rafehi, Muhammad, Voss, Jan H., Garg, Jaspal, Schlegel, Jonathan G., Abdelrahman, Aliaa, Kehraus, Stefan, Reher, Raphael, Küppers, Jim, Sylvester, Katharina, Hinz, Sonja, Matthey, Michaela, Wenzel, Daniela, Fleischmann, Bernd K., Pfeifer, Alexander, Inoue, Asuka, Gütschow, Michael, König, Gabriele M., Müller, Christa E.
Publicado 2020