Specificity of presenilin‐1‐ and presenilin‐2‐dependent γ‐secretases towards substrate processing

por Stanga, Serena, Vrancx, Céline, Tasiaux, Bernadette, Marinangeli, Claudia, Karlström, Helena, Kienlen‐Campard, Pascal
Publicado 2017

Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy

por Doyle, James J., Vrancx, Celine, Maios, Claudia, Labarre, Audrey, Patten, Shunmoogum A., Parker, J. Alex
Publicado 2020

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates

por Papadopoulos, Nicolas, Suelves, Nuria, Perrin, Florian, Vadukul, Devkee M., Vrancx, Céline, Constantinescu, Stefan N., Kienlen-Campard, Pascal
Publicado 2022

Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites

por Vrijsen, Stephanie, Vrancx, Céline, Del Vecchio, Mara, Swinnen, Johannes V., Agostinis, Patrizia, Winderickx, Joris, Vangheluwe, Peter, Annaert, Wim
Publicado 2022

Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes

por Contino, Sabrina, Suelves, Nuria, Vrancx, Céline, Vadukul, Devkee M., Payen, Valery L., Stanga, Serena, Bertrand, Luc, Kienlen-Campard, Pascal
Publicado 2021

An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β

por Vadukul, Devkee M., Vrancx, Céline, Burguet, Pierre, Contino, Sabrina, Suelves, Nuria, Serpell, Louise C., Quinton, Loïc, Kienlen-Campard, Pascal
Publicado 2021

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

por Perrin, Florian, Papadopoulos, Nicolas, Suelves, Nuria, Opsomer, Rémi, Vadukul, Devkee M., Vrancx, Céline, Smith, Steven O., Vertommen, Didier, Kienlen-Campard, Pascal, Constantinescu, Stefan N.
Publicado 2020

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

por Perrin, Florian, Papadopoulos, Nicolas, Suelves, Nuria, Opsomer, Rémi, Vadukul, Devkee M., Vrancx, Céline, Smith, Steven O., Vertommen, Didier, Kienlen-Campard, Pascal, Constantinescu, Stefan N.
Publicado 2021

Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies

por Vrancx, Céline, Vadukul, Devkee M., Suelves, Nuria, Contino, Sabrina, D’Auria, Ludovic, Perrin, Florian, van Pesch, Vincent, Hanseeuw, Bernard, Quinton, Loïc, Kienlen-Campard, Pascal
Publicado 2021

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

por Opsomer, Rémi, Contino, Sabrina, Perrin, Florian, Gualdani, Roberta, Tasiaux, Bernadette, Doyen, Pierre, Vergouts, Maxime, Vrancx, Céline, Doshina, Anna, Pierrot, Nathalie, Octave, Jean-Noël, Gailly, Philippe, Stanga, Serena, Kienlen-Campard, Pascal
Publicado 2020

Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology

por Suelves, Nuria, Saleki, Shirine, Ibrahim, Tasha, Palomares, Debora, Moonen, Sebastiaan, Koper, Marta J., Vrancx, Céline, Vadukul, Devkee M., Papadopoulos, Nicolas, Viceconte, Nikenza, Claude, Eloïse, Vandenberghe, Rik, von Arnim, Christine A. F., Constantinescu, Stefan N., Thal, Dietmar Rudolf, Decottignies, Anabelle, Kienlen-Campard, Pascal
Publicado 2023