Genetics of rheumatic disease

por Clarke, Alex, Vyse, Timothy J
Publicado 2009

Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus

por Vyse, Timothy J., Cunninghame Graham, Deborah S.
Publicado 2020

Genetics of SLE: does this explain susceptibility and severity across racial groups?

por Demkova, Karin, Morris, David L, Vyse, Timothy J
Publicado 2022

The genetics of lupus: a functional perspective

por Guerra, Sandra G, Vyse, Timothy J, Cunninghame Graham, Deborah S
Publicado 2012

Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease

por Odhams, Christopher A., Cunninghame Graham, Deborah S., Vyse, Timothy J.
Publicado 2017

The complement receptor 3 (CD11b/CD18) agonist Leukadherin‐1 suppresses human innate inflammatory signalling

por Roberts, A. L., Fürnrohr, B. G., Vyse, T. J., Rhodes, B.
Publicado 2016

Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment

por Fürnrohr, Barbara G., Rhodes, Benjamin, Munoz, Luis E., Weiß, Katrin, Vyse, Tim J., Schett, Georg
Publicado 2015

Dysregulated CD46 shedding interferes with Th1‐contraction in systemic lupus erythematosus

por Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Le Friec, Gaelle, Kemper, Claudia, Vyse, Timothy J.
Publicado 2017

Dense mapping of IL18 shows no association in SLE

por Guerra, Sandra G., Morris, David L., Gateva, Vesela, Graham, Robert R., Vyse, Timothy J., Cunninghame Graham, Deborah S.
Publicado 2011

Determination of the Loss of Function Complement C4 Exon 29 CT Insertion Using a Novel Paralog-Specific Assay in Healthy UK and Spanish Populations

por Boteva, Lora, Wu, Yee Ling, Cortes-Hernández, Josefina, Martin, Javier, Vyse, Timothy J., Fernando, Michelle M. A.
Publicado 2011

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

por Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J
Publicado 2015

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

por Rhodes, Benjamin, Fürnrohr, Barbara G, Roberts, Amy L, Tzircotis, George, Schett, Georg, Spector, Tim D, Vyse, Timothy J
Publicado 2012

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

por Roberts, Amy L, Thomas, Ellen RA, Bhosle, Shriram, Game, Laurence, Obraztsova, Olga, Aitman, Timothy J, Vyse, Timothy J, Rhodes, Benjamin
Publicado 2014

Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation

por Vester, Susan K., Beavil, Rebecca L., Lynham, Steven, Beavil, Andrew J., Cunninghame Graham, Deborah S., McDonnell, James M., Vyse, Timothy J.
Publicado 2021

Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE

por Morris, D L, Graham, R R, Erwig, L-P, Gaffney, P M, Moser, K L, Behrens, T W, Vyse, T J, Graham, D S Cunninghame
Publicado 2009

A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation

por Rhodes, Benjamin, Merriman, Marilyn E., Harrison, Andrew, Nissen, Michael J., Smith, Malcolm, Stamp, Lisa, Steer, Sophia, Merriman, Tony R., Vyse, Timothy J.
Publicado 2010

UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases

por Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Boeltz, Sebastian, Gordon, Patrick A., Spector, Timothy D., Lehner, Paul J., Walczak, Henning, Vyse, Timothy J.
Publicado 2015

Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1

por Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Zou, Lu, Khamashta, Munther, Gordon, Patrick A., Pitzalis, Costantino, Vyse, Timothy J., D’Cruz, David P.
Publicado 2016

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

por Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip L., Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D.
Publicado 2008

Lack of Serologic Evidence of Neospora caninum in Humans, England

por McCann, Catherine M., Vyse, Andrew J., Salmon, Roland L, Thomas, Daniel, Williams, Diana J.L., McGarry, John W., Pebody, Richard, Trees, Alexander J.
Publicado 2008