Disease-Toxicant Interactions in Manganese Exposed Huntington Disease Mice: Early Changes in Striatal Neuron Morphology and Dopamine Metabolism

por Madison, Jennifer L., Wegrzynowicz, Michal, Aschner, Michael, Bowman, Aaron B.
Publicado 2012

L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils

por Migdalska‐Richards, Anna, Wegrzynowicz, Michal, Harrison, Ian F., Verona, Guglielmo, Bellotti, Vittorio, Spillantini, Maria Grazia, Schapira, Anthony H. V.
Publicado 2020

The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice

por Migdalska-Richards, Anna, Wegrzynowicz, Michal, Rusconi, Raffaella, Deangeli, Giulio, Di Monte, Donato A, Spillantini, Maria G, Schapira, Anthony H V
Publicado 2017

Salivary α‐Synuclein RT‐QuIC Correlates with Disease Severity in de novo Parkinson's Disease

por Vivacqua, Giorgio, Mason, Matthew, De Bartolo, Maria Ilenia, Węgrzynowicz, Michal, Calò, Laura, Belvisi, Daniele, Suppa, Antonio, Fabbrini, Giovanni, Berardelli, Alfredo, Spillantini, MariaGrazia
Publicado 2022

CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice

por Caló, Laura, Hidari, Eric, Wegrzynowicz, Michal, Dalley, Jeffrey W, Schneider, Bernard L, Podgajna, Martyna, Anichtchik, Oleg, Carlson, Emma, Klenerman, David, Spillantini, Maria Grazia
Publicado 2021

Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model

por Wegrzynowicz, Michal, Bar-On, Dana, Calo’, Laura, Anichtchik, Oleg, Iovino, Mariangela, Xia, Jing, Ryazanov, Sergey, Leonov, Andrei, Giese, Armin, Dalley, Jeffrey W., Griesinger, Christian, Ashery, Uri, Spillantini, Maria Grazia
Publicado 2019

Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, dou...

por Levin, Johannes, Sing, Nand, Melbourne, Sue, Morgan, Amber, Mariner, Carla, Spillantini, Maria Grazia, Wegrzynowicz, Michal, Dalley, Jeffrey W., Langer, Simon, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Schmidt, Felix, Weckbecker, Daniel, Prager, Kai, Matthias, Torsten, Giese, Armin
Publicado 2022

Potent but transient immunosuppression of T-cells is a general feature of CD71(+) erythroid cells

por Grzywa, Tomasz M., Sosnowska, Anna, Rydzynska, Zuzanna, Lazniewski, Michal, Plewczynski, Dariusz, Klicka, Klaudia, Malecka-Gieldowska, Milena, Rodziewicz-Lurzynska, Anna, Ciepiela, Olga, Justyniarska, Magdalena, Pomper, Paulina, Grzybowski, Marcin M., Blaszczyk, Roman, Wegrzynowicz, Michal, Tomaszewska, Agnieszka, Basak, Grzegorz, Golab, Jakub, Nowis, Dominika
Publicado 2021