Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR

por Simons, Jan Fredrik, Lim, Yoong Wearn, Carter, Kyle P., Wagner, Ellen K., Wayham, Nicholas, Adler, Adam S., Johnson, David S.
Publicado 2020

Prior exposure to Bordetella species as an exclusion criterion in the baboon model of pertussis

por NGUYEN, Annalee W., WAGNER, Ellen K., POSADA, Luciano, LIU, Xinlei, CONNELLY, Sheila, PAPIN, James F., WOLF, Roman F., KALEKO, Michael, MAYNARD, Jennifer A.
Publicado 2016

Massively parallel interrogation and mining of natively paired human TCRαβ repertoires

por Spindler, Matthew J., Nelson, Ayla L., Wagner, Ellen K., Oppermans, Natasha, Bridgeman, John S., Heather, James M., Adler, Adam S., Asensio, Michael A., Edgar, Robert C., Lim, Yoong Wearn, Meyer, Everett H., Hawkins, Robert E., Cobbold, Mark, Johnson, David S.
Publicado 2020

A Potent Recombinant Polyclonal Antibody Therapeutic for Protection Against New Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern

por Wayham, Nicholas P, Niedecken, Ariel R, Simons, Jan Fredrik, Chiang, Yao Y, Medina-Cucurella, Angélica V, Mizrahi, Rena A, Wagner, Ellen K, Gras, Ashley, Segal, Ilana, Witte, Peyton, Enstrom, Alexis, Bountouvas, Aristea, Nelson, Sabrina M, Weinberger, Tess, Tan, David, Asensio, Michael A, Subramanian, Alagu, Lim, Yoong Wearn, Adler, Adam S, Keating, Sheila M
Publicado 2023

GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2

por Mizrahi, Rena A., Lin, Wendy Y., Gras, Ashley, Niedecken, Ariel R., Wagner, Ellen K., Keating, Sheila M., Ikon, Nikita, Manickam, Vishal A., Asensio, Michael A., Leong, Jackson, Medina-Cucurella, Angelica V., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Leong, Renee, Lim, Yoong Wearn, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Wayham, Nicholas, Büscher, Dirk, Terencio, Jose Vicente, Germanio, Clara Di, Chamow, Steven M., Olson, Charles, Pino, Paula A., Park, Jun-Gyu, Hicks, Amberlee, Ye, Chengjin, Garcia-Vilanova, Andreu, Martinez-Sobrido, Luis, Torrelles, Jordi B., Johnson, David S., Adler, Adam S.
Publicado 2022

Generation of recombinant hyperimmune globulins from diverse B-cell repertoires

por Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Wearn Lim, Yoong, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Fredrik Simons, Jan, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Vingsbo Lundberg, Carina, Büscher, Dirk, Vicente Terencio, Jose, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V.F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.
Publicado 2021