The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

por Spangenberg, Thomas, Burrows, Jeremy N., Kowalczyk, Paul, McDonald, Simon, Wells, Timothy N. C., Willis, Paul
Publicado 2013

A Proposed Target Product Profile and Developmental Cascade for New Cryptosporidiosis Treatments

por Huston, Christopher D., Spangenberg, Thomas, Burrows, Jeremy, Willis, Paul, Wells, Timothy N. C., van Voorhis, Wesley
Publicado 2015

Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?

por Hemingway, Janet, Shretta, Rima, Wells, Timothy N. C., Bell, David, Djimdé, Abdoulaye A., Achee, Nicole, Qi, Gao
Publicado 2016

Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

por Rufener, Reto, Dick, Luca, D'Ascoli, Laura, Ritler, Dominic, Hizem, Amani, Wells, Timothy N.C., Hemphill, Andrew, Lundström-Stadelmann, Britta
Publicado 2018

Reassessing therapeutic antibodies for neglected and tropical diseases

por Hooft van Huijsduijnen, Rob, Kojima, Somei, Carter, Dee, Okabe, Hisafumi, Sato, Akihide, Akahata, Wataru, Wells, Timothy N. C., Katsuno, Kei
Publicado 2020

Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C–C Chemokine Receptors in Human Monocytes

por Sica, Antonio, Saccani, Alessandra, Borsatti, Alessandro, Power, Christine A., Wells, Timothy N.C., Luini, Walter, Polentarutti, Nadia, Sozzani, Silvano, Mantovani, Alberto
Publicado 1997

Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm

por Preston, Sarah, Jiao, Yaqing, Jabbar, Abdul, McGee, Sean L., Laleu, Benoît, Willis, Paul, Wells, Timothy N.C., Gasser, Robin B.
Publicado 2016

RANTES and Monocyte Chemoattractant Protein–1 (MCP-1) Play an Important Role in the Inflammatory Phase of Crescentic Nephritis, but Only MCP-1 Is Involved in Crescent Formation and...

por Lloyd, Clare M., Minto, Andrew W., Dorf, Martin E., Proudfoot, Amanda, Wells, Timothy N.C., Salant, David J., Gutierrez-Ramos, Jose-Carlos
Publicado 1997

A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria

por Burrows, Jeremy, Slater, Hannah, Macintyre, Fiona, Rees, Sarah, Thomas, Anna, Okumu, Fredros, Hooft van Huijsduijnen, Rob, Duparc, Stephan, Wells, Timothy N. C.
Publicado 2018

Identification of chlorophyll a-b binding protein AB96 as a novel TGFβ1 neutralizing agent

por Lynham, Steven, Freile, Fabio Grundland, Puri, Natasha M., O’Reilly, Nicola, Mitchell, Graham H., Wells, Timothy N. C., Willcox, Merlin, Beatson, Richard
Publicado 2021

Orally Active Antischistosomal Early Leads Identified from the Open Access Malaria Box

por Ingram-Sieber, Katrin, Cowan, Noemi, Panic, Gordana, Vargas, Mireille, Mansour, Nuha R., Bickle, Quentin D., Wells, Timothy N. C., Spangenberg, Thomas, Keiser, Jennifer
Publicado 2014

Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells

por Power, Christine A., Church, Dennis J., Meyer, Alexandra, Alouani, Sami, Proudfoot, Amanda E.I., Clark-Lewis, Ian, Sozzani, Silvano, Mantovani, Alberto, Wells, Timothy N.C.
Publicado 1997

New developments in anti-malarial target candidate and product profiles

por Burrows, Jeremy N., Duparc, Stephan, Gutteridge, Winston E., Hooft van Huijsduijnen, Rob, Kaszubska, Wiweka, Macintyre, Fiona, Mazzuri, Sébastien, Möhrle, Jörg J., Wells, Timothy N. C.
Publicado 2017

Erratum to: New developments in anti-malarial target candidate and product profiles

por Burrows, Jeremy N., Duparc, Stephan, Gutteridge, Winston E., van Huijsduijnen, Rob Hooft, Kaszubska, Wiweka, Macintyre, Fiona, Mazzuri, Sébastien, Möhrle, Jörg J., Wells, Timothy N. C.
Publicado 2017

A Key Role for Cc Chemokine Receptor 4 in Lipopolysaccharide-Induced Endotoxic Shock

por Chvatchko, Yolande, Hoogewerf, Arlene J., Meyer, Alexandra, Alouani, Sami, Juillard, Pierre, Buser, Raphaele, Conquet, Francois, Proudfoot, Amanda E.I., Wells, Timothy N.C., Power, Christine A.
Publicado 2000

Dendritic Cells Are Recruited into the Airway Epithelium during the Inflammatory Response to a Broad Spectrum of Stimuli

por McWilliam, Andrew S., Napoli, Sylvia, Marsh, Amanda M., Pemper, Francis L., Nelson, Delia J., Pimm, Carolyn L., Stumbles, Philip A., Wells, Timothy N.C., Holt, Patrick G.
Publicado 1996

Open source drug discovery – A limited tutorial

por ROBERTSON, MURRAY N., YLIOJA, PAUL M., WILLIAMSON, ALICE E., WOELFLE, MICHAEL, ROBINS, MICHAEL, BADIOLA, KATRINA A., WILLIS, PAUL, OLLIARO, PIERO, WELLS, TIMOTHY N. C., TODD, MATTHEW H.
Publicado 2014

Similarities and Differences in RANTES- and (AOP)-RANTES–triggered Signals: Implications for Chemotaxis

por Rodríguez-Frade, José M., Vila-Coro, Antonio J., Martín, Ana, Nieto, Marta, Sánchez-Madrid, Francisco, Proudfoot, Amanda E.I., Wells, Timothy N.C., Martínez-A, Carlos, Mellado, Mario
Publicado 1999

An Interleukin 5 Mutant Distinguishes between Two Functional Responses in Human Eosinophils

por McKinnon, Murray, Page, Kevin, Uings, Iain J., Banks, Martyn, Fattah, Dilniya, Proudfoot, Amanda E.I., Graber, Pierre, Arod, Christian, Fish, Richard, Wells, Timothy N.C., Solari, Roberto
Publicado 1997

Glycosaminoglycan analogs as a novel anti-inflammatory strategy

por Severin, India C., Soares, Adriano, Hantson, Jennifer, Teixeira, Mauro, Sachs, Daniela, Valognes, Delphine, Scheer, Alexander, Schwarz, Matthias K., Wells, Timothy N. C., Proudfoot, Amanda E. I., Shaw, Jeffrey
Publicado 2012