Convergent pathways in Parkinson’s disease

por Cherubini, Marta, Wade-Martins, Richard
Publicado 2017

Patient-derived iPSC models of Friedreich ataxia: a new frontier for understanding disease mechanisms and therapeutic application

por Maheshwari, Saumya, Vilema-Enríquez, Gabriela, Wade-Martins, Richard
Publicado 2023

LRRK2 interacts with the vacuolar-type H(+)-ATPase pump a1 subunit to regulate lysosomal function

por Wallings, Rebecca, Connor-Robson, Natalie, Wade-Martins, Richard
Publicado 2019

“LRRK2: Autophagy and Lysosomal Activity”

por Madureira, Marta, Connor-Robson, Natalie, Wade-Martins, Richard
Publicado 2020

An S/MAR-based infectious episomal genomic DNA expression vector provides long-term regulated functional complementation of LDLR deficiency

por Lufino, Michele M.P., Manservigi, Roberto, Wade-Martins, Richard
Publicado 2007

Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

por Roberts, Rosalind F., Wade-Martins, Richard, Alegre-Abarrategui, Javier
Publicado 2015

Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

por Fields, Carroll Rutherford, Bengoa-Vergniory, Nora, Wade-Martins, Richard
Publicado 2019

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

por Fernandes, Hugo J. R., Ryan, Brent J., Wade-Martins, Richard
Publicado 2016

The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

por Booth, Heather D.E., Hirst, Warren D., Wade-Martins, Richard
Publicado 2017

What Is Our Understanding of the Influence of Gut Microbiota on the Pathophysiology of Parkinson’s Disease?

por Hill, Amaryllis E., Wade-Martins, Richard, Burnet, Philip W. J.
Publicado 2021

R-loops Associated with Triplet Repeat Expansions Promote Gene Silencing in Friedreich Ataxia and Fragile X Syndrome

por Groh, Matthias, Lufino, Michele M. P., Wade-Martins, Richard, Gromak, Natalia
Publicado 2014

Protein-protein interaction networks identify targets which rescue the MPP(+) cellular model of Parkinson’s disease

por Keane, Harriet, Ryan, Brent J., Jackson, Brendan, Whitmore, Alan, Wade-Martins, Richard
Publicado 2015

Alpha-synuclein oligomers: a new hope

por Bengoa-Vergniory, Nora, Roberts, Rosalind F., Wade-Martins, Richard, Alegre-Abarrategui, Javier
Publicado 2017

Impaired dopamine release in Parkinson’s disease

por Cramb, Kaitlyn M L, Beccano-Kelly, Dayne, Cragg, Stephanie J, Wade-Martins, Richard
Publicado 2023

Human‐Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons

por Monzón‐Sandoval, Jimena, Poggiolini, Ilaria, Ilmer, Tobias, Wade‐Martins, Richard, Webber, Caleb, Parkkinen, Laura
Publicado 2020

Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release

por Burley, Sarah, Beccano-Kelly, Dayne A., Talbot, Kevin, Llana, Oscar Cordero, Wade-Martins, Richard
Publicado 2022

Impaired intracellular trafficking defines early Parkinson's disease

por Hunn, Benjamin H.M., Cragg, Stephanie J., Bolam, J. Paul, Spillantini, Maria-Grazia, Wade-Martins, Richard
Publicado 2015

Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases

por Salman, Mootaz M., Al-Obaidi, Zaid, Kitchen, Philip, Loreto, Andrea, Bill, Roslyn M., Wade-Martins, Richard
Publicado 2021

Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers

por Wu, Shenjie, Hernandez Villegas, Nancy C, Sirkis, Daniel W, Thomas-Wright, Iona, Wade-Martins, Richard, Schekman, Randy
Publicado 2023

The infectious BAC genomic DNA expression library: a high capacity vector system for functional genomics

por Lufino, Michele M. P., Edser, Pauline A. H., Quail, Michael A., Rice, Stephen, Adams, David J., Wade-Martins, Richard
Publicado 2016