Molecular pathology of human prion disease

por Wadsworth, Jonathan D. F., Collinge, John
Publicado 2010

Recent Advances in Understanding Mammalian Prion Structure: A Mini Review

por Terry, Cassandra, Wadsworth, Jonathan D. F.
Publicado 2019

Prion strains viewed through the lens of cryo-EM

por Manka, Szymon W., Wenborn, Adam, Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2022

Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy

por Jackson, Graham S., Linehan, Jacqueline, Brandner, Sebastian, Asante, Emmanuel A., Wadsworth, Jonathan D. F., Collinge, John
Publicado 2022

The origin of the prion agent of kuru: molecular and biological strain typing

por Wadsworth, Jonathan D.F., Joiner, Susan, Linehan, Jacqueline M., Asante, Emmanuel A., Brandner, Sebastian, Collinge, John
Publicado 2008

Isolation of Proteinase K-Sensitive Prions Using Pronase E and Phosphotungstic Acid

por D'Castro, Laura, Wenborn, Adam, Gros, Nathalie, Joiner, Susan, Cronier, Sabrina, Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2010

A structural basis for prion strain diversity

por Manka, Szymon W., Wenborn, Adam, Betts, Jemma, Joiner, Susan, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2023

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin

por Cronier, Sabrina, Gros, Nathalie, Tattum, M. Howard, Jackson, Graham S., Clarke, Anthony R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2008

2.7 Å cryo-EM structure of ex vivo RML prion fibrils

por Manka, Szymon W., Zhang, Wenjuan, Wenborn, Adam, Betts, Jemma, Joiner, Susan, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2022

Physical, chemical and kinetic factors affecting prion infectivity

por Properzi, Francesca, Badhan, Anjna, Klier, Steffi, Schmidt, Christian, Klöhn, Peter C., Wadsworth, Jonathan D. F., Clarke, Anthony R., Jackson, Graham S., Collinge, John
Publicado 2016

Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro

por Terry, Cassandra, Harniman, Robert L., Sells, Jessica, Wenborn, Adam, Joiner, Susan, Saibil, Helen R., Miles, Mervyn J., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2019

Soluble Aβ aggregates can inhibit prion propagation

por Sarell, Claire J., Quarterman, Emma, Yip, Daniel C.-M., Terry, Cassandra, Nicoll, Andrew J., Wadsworth, Jonathan D. F., Farrow, Mark A., Walsh, Dominic M., Collinge, John
Publicado 2017

Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein

por Joiner, Susan, Asante, Emmanuel A., Linehan, Jacqueline M., Brock, Lara, Brandner, Sebastian, Bellworthy, Susan J., Simmons, Marion M., Hope, James, Collinge, John, Wadsworth, Jonathan D.F.
Publicado 2018

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

por Asante, Emmanuel A., Gowland, Ian, Grimshaw, Andrew, Linehan, Jacqueline M., Smidak, Michelle, Houghton, Richard, Osiguwa, Olufunmilayo, Tomlinson, Andrew, Joiner, Susan, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2009

Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein

por Asante, Emmanuel A., Linehan, Jacqueline M., Smidak, Michelle, Tomlinson, Andrew, Grimshaw, Andrew, Jeelani, Asif, Jakubcova, Tatiana, Hamdan, Shyma, Powell, Caroline, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2013

Central and peripheral pathology of kuru: pathological analysis of a recent case and comparison with other forms of human prion disease

por Brandner, Sebastian, Whitfield, Jerome, Boone, Ken, Puwa, Anderson, O'Malley, Catherine, Linehan, Jacqueline M., Joiner, Susan, Scaravilli, Francesco, Calder, Ian, Alpers, Michael P., Wadsworth, Jonathan D.F., Collinge, John
Publicado 2008

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

por Sandberg, Malin K., Al-Doujaily, Huda, Sigurdson, Christina J., Glatzel, Markus, O'Malley, Catherine, Powell, Caroline, Asante, Emmanuel A., Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2010

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS

por Asante, Emmanuel A., Grimshaw, Andrew, Smidak, Michelle, Jakubcova, Tatiana, Tomlinson, Andrew, Jeelani, Asif, Hamdan, Shyma, Powell, Caroline, Joiner, Susan, Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2015

Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years

por Rudge, Peter, Jaunmuktane, Zane, Adlard, Peter, Bjurstrom, Nina, Caine, Diana, Lowe, Jessica, Norsworthy, Penny, Hummerich, Holger, Druyeh, Ron, Wadsworth, Jonathan D. F., Brandner, Sebastian, Hyare, Harpreet, Mead, Simon, Collinge, John
Publicado 2015

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

por Asante, Emmanuel A., Linehan, Jacqueline M., Tomlinson, Andrew, Jakubcova, Tatiana, Hamdan, Shyma, Grimshaw, Andrew, Smidak, Michelle, Jeelani, Asif, Nihat, Akin, Mead, Simon, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2020