Overview of Biomarkers and Surrogate Endpoints in Drug Development

por Wagner, John A.
Publicado 2002

Chasing My Cure A Doctor's Race to Turn Hope Into Action by David Fajgenbaum Review by John A. Wagner MD, PhD

por Wagner, John A.
Publicado 2020

Surrogate Endpoints in Medicine

por Srivastava, Sudhir, Wagner, John A.
Publicado 2002

The nervous system: Orchestra conductor in cancer, regeneration, inflammation and immunity

por Hondermarck, Hubert, Huang, Pearl S., Wagner, John A.
Publicado 2021

Wearable Devices in Clinical Trials: Hype and Hypothesis

por Izmailova, Elena S., Wagner, John A., Perakslis, Eric D.
Publicado 2018

COVID‐19 vaccines and treatments: When speed is necessary and not enough

por Grasela, Thaddeus H., Price, David A., Wagner, John A.
Publicado 2021

What Can Be Learned From Crowdsourced Population Asparagus Urinary Odor Kinetics?

por Facius, Axel, Atkinson, Linda A., Hanna, Kelly, Coombes, Mai Chi, Lahu, Gezim, Wagner, John A.
Publicado 2019

Study protocol: A comparison of mobile and clinic‐based spirometry for capturing the treatment effect in moderate asthma

por Izmailova, Elena S., Kilian, Rachel, Bakker, Jessie P., Evans, Shawna, Scotina, Anthony D., Reiss, Theodore F., Singh, Dave, Wagner, John A.
Publicado 2023

The Foundation for the National Institutes of Health Biomarkers Consortium: Past Accomplishments and New Strategic Direction

por Menetski, Joseph P., Hoffmann, Steven C., Cush, Stephanie S., Kamphaus, Tania Nayak, Austin, Christopher P., Herrling, Paul L., Wagner, John A.
Publicado 2019

Evaluation of Wearable Digital Devices in a Phase I Clinical Trial

por Izmailova, Elena S., McLean, Ian L., Bhatia, Gaurav, Hather, Greg, Cantor, Matthew, Merberg, David, Perakslis, Eric D., Benko, Christopher, Wagner, John A.
Publicado 2019

Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development

por Wagner, John A., Dahlem, Andrew M., Hudson, Lynn D., Terry, Sharon F., Altman, Russ B., Gilliland, C. Taylor, DeFeo, Christopher, Austin, Christopher P.
Publicado 2017

Continuous Monitoring Using a Wearable Device Detects Activity‐Induced Heart Rate Changes After Administration of Amphetamine

por Izmailova, Elena S., McLean, Ian L., Hather, Greg, Merberg, David, Homsy, Jason, Cantor, Matthew, Volfson, Dmitri, Bhatia, Gaurav, Perakslis, Eric D., Benko, Christopher, Wagner, John A.
Publicado 2019

Crowdsourced Asparagus Urinary Odor Population Kinetics

por Ramamoorthy, Anuradha, Sadler, Brian M., van Hasselt, J.G. Coen, Elassaiss‐Schaap, Jeroen, Kasichayanula, Sreeneeranj, Edwards, Alena Y., van der Graaf, Piet H., Zhang, Lei, Wagner, John A.
Publicado 2017

Fit‐for‐Purpose Biometric Monitoring Technologies: Leveraging the Laboratory Biomarker Experience

por Godfrey, Alan, Vandendriessche, Benjamin, Bakker, Jessie P., Fitzer‐Attas, Cheryl, Gujar, Ninad, Hobbs, Matthew, Liu, Qi, Northcott, Carrie A., Parks, Virginia, Wood, William A., Zipunnikov, Vadim, Wagner, John A., Izmailova, Elena S.
Publicado 2020

Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males

por Ankrom, Wendy, Bondiskey, Phung, Li, Chi‐Chung, Palcza, John, Liu, Wen, Dockendorf, Marissa F., Matthews, Catherine, Panebianco, Deborah, Reynders, Tom, Wagner, John A., Jakate, Abhijeet, Mesens, Sofie, Kraft, Walter K., Marcantonio, Eugene E.
Publicado 2020

A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer

por Lush, Richard M., Patnaik, Amita, Sullivan, Daniel, Papadopoulos, Kyriakos P., Trucksis, Michele, McCrea, Jacqueline, Cerchio, Kristine, Li, Xiaodong, Stroh, Mark, Selverian, Diana, Orford, Keith, Ebbinghaus, Scot, Agrawal, Nancy, Iwamoto, Marian, Wagner, John A., Tolcher, Anthony
Publicado 2012

Pharmacokinetics and Pharmacodynamics of Omarigliptin, a Once‐Weekly Dipeptidyl Peptidase‐4 (DPP‐4) Inhibitor, After Single and Multiple Doses in Healthy Subjects

por Krishna, Rajesh, Addy, Carol, Tatosian, Daniel, Glasgow, Xiaoli S., Gendrano III, Isaias Noel, Robberechts, Martine, Haazen, Wouter, de Hoon, J.N., Depré, Marleen, Martucci, Ashley, Peng, Joanna Z., Johnson‐Levonas, Amy O., Wagner, John A., Stoch, S. Aubrey
Publicado 2016

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

por Thomas, Tiffany, Zhou, Haihong, Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, Liu, Yang, Jumes, Patricia, Wagner, John A., Hubbard, Brian, Previs, Stephen F., Roddy, Thomas, Johnson-Levonas, Amy O., Gutstein, David E., Marcovina, Santica M., Rader, Daniel J., Ginsberg, Henry N., Millar, John S., Reyes-Soffer, Gissette
Publicado 2017

Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E

por Millar, John S., Lassman, Michael E., Thomas, Tiffany, Ramakrishnan, Rajasekhar, Jumes, Patricia, Dunbar, Richard L., deGoma, Emil M., Baer, Amanda L., Karmally, Wahida, Donovan, Daniel S., Rafeek, Hashmi, Wagner, John A., Holleran, Stephen, Obunike, Joseph, Liu, Yang, Aoujil, Soumia, Standiford, Taylor, Gutstein, David E., Ginsberg, Henry N., Rader, Daniel J., Reyes-Soffer, Gissette
Publicado 2017

Remote Digital Monitoring for Medical Product Development

por Izmailova, Elena S., Wagner, John A., Ammour, Nadir, Amondikar, Ninad, Bell‐Vlasov, Andrea, Berman, Steven, Bloomfield, Dan, Brady, Linda S., Cai, Xuemei, Calle, Roberto A., Campbell, Michelle, Cerreta, Francesca, Clay, Ieuan, Foschini, Luca, Furlong, Pat, Goldel, Rob, Goldsack, Jennifer S., Groenen, Peter M.A., Folarin, Amos, Heemskerk, Jill, Honig, Peter, Hotopf, Matthew, Kamphaus, Tania, Karlin, Daniel R., Leptak, Christopher, Liu, Qi, Manji, Husseini, Mather, Robert J., Menetski, Joseph P., Narayan, Vaibhav A., Papadopoulos, Elektra, Patel, Bakul, Patrick‐Lake, Bray, Podichetty, Jagdeep T., Pratap, Abhishek, Servais, Laurent, Stephenson, Diane, Tenaerts, Pam, Tromberg, Bruce J., Usdin, Steve, Vasudevan, Srikanth, Zipunnikov, Vadim, Hoffmann, Steven C.
Publicado 2020