Internalized Functional DNA Aptamers as Alternative Cancer Therapies

por Marshall, Morgan L., Wagstaff, Kylie M.
Publicado 2020

Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?

por Jans, David A., Wagstaff, Kylie M.
Publicado 2020

The broad spectrum host-directed agent ivermectin as an antiviral for SARS-CoV-2 ?

por Jans, David A., Wagstaff, Kylie M.
Publicado 2021

The Nuclear Transporter Importin 13 Can Regulate Stress-Induced Cell Death through the Clusterin/KU70 Axis

por Gajewska, Katarzyna A., Jans, David A., Wagstaff, Kylie M.
Publicado 2023

Enhanced tumour cell nuclear targeting in a tumour progression model

por Nastasie, Michael S, Thissen, Helmut, Jans, David A, Wagstaff, Kylie M
Publicado 2015

Interactome of the negative regulator of nuclear import BRCA1-binding protein 2

por Fatima, Shadma, Wagstaff, Kylie M., Loveland, Kate L., Jans, David A.
Publicado 2015

Transcriptomic profile dataset of embryonic stem cells (Wild-type and IPO13-Knock Out) with and without oxidative stress

por Gajewska, Katarzyna A., Ramialison, Mirana, Wagstaff, Kylie M., Jans, David A.
Publicado 2022

Sortase A transpeptidation produces seamless, unbranched biotinylated nanobodies for multivalent and multifunctional applications

por Obeng, Eugene M., Steer, David L., Fulcher, Alex J., Wagstaff, Kylie M.
Publicado 2023

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus

por Wagstaff, Kylie M., Sivakumaran, Haran, Heaton, Steven M., Harrich, David, Jans, David A.
Publicado 2012

Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture

por Walunj, Sujata B., Wang, Chunxiao, Wagstaff, Kylie M., Patankar, Swati, Jans, David A.
Publicado 2022

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro

por Caly, Leon, Druce, Julian D., Catton, Mike G., Jans, David A., Wagstaff, Kylie M.
Publicado 2020

Nuclear Import of β-Dystroglycan Is Facilitated by Ezrin-Mediated Cytoskeleton Reorganization

por Vásquez-Limeta, Alejandra, Wagstaff, Kylie M., Ortega, Arturo, Crouch, Dorothy H., Jans, David A., Cisneros, Bulmaro
Publicado 2014

Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain

por Rowe, Caitlin L., Wagstaff, Kylie M., Oksayan, Sibil, Glover, Dominic J., Jans, David A., Moseley, Gregory W.
Publicado 2016

High Throughput Screening Targeting the Dengue NS3-NS5 Interface Identifies Antivirals against Dengue, Zika and West Nile Viruses

por Yang, Sundy N. Y., Maher, Belinda, Wang, Chunxiao, Wagstaff, Kylie M., Fraser, Johanna E., Jans, David A.
Publicado 2022

Increased In Vivo Exposure of N-(4-Hydroxyphenyl) Retinamide (4-HPR) to Achieve Plasma Concentrations Effective against Dengue Virus

por Martin, Alexander J., Shackleford, David M., Charman, Susan A., Wagstaff, Kylie M., Porter, Christopher J. H., Jans, David A.
Publicado 2023

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

por Wagstaff, Kylie M., Headey, Stephen, Telwatte, Sushama, Tyssen, David, Hearps, Anna C., Thomas, David R., Tachedjian, Gilda, Jans, David A.
Publicado 2018

High-Throughput Screening to Identify Inhibitors of Plasmodium falciparum Importin α

por Walunj, Sujata B., Dias, Manisha M., Kaur, Chhaminder, Wagstaff, Kylie M., Dey, Vishakha, Hick, Caroline, Patankar, Swati, Jans, David A.
Publicado 2022

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus

por Al-Wassiti, Hareth A., Thomas, David R., Wagstaff, Kylie M., Fabb, Stewart A., Jans, David A., Johnston, Angus P., Pouton, Colin W.
Publicado 2021

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells

por Lundberg, Lindsay, Pinkham, Chelsea, de la Fuente, Cynthia, Brahms, Ashwini, Shafagati, Nazly, Wagstaff, Kylie M., Jans, David A., Tamir, Sharon, Kehn-Hall, Kylene
Publicado 2016

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

por Shechter, Sharon, Thomas, David R., Lundberg, Lindsay, Pinkham, Chelsea, Lin, Shih-Chao, Wagstaff, Kylie M., Debono, Aaron, Kehn-Hall, Kylene, Jans, David A.
Publicado 2017