Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

por Wahl, Geoffrey M., Spike, Benjamin T.
Publicado 2017

Selective Entrapment of Extrachromosomally Amplified DNA by Nuclear Budding and Micronucleation during S Phase

por Shimizu, Noriaki, Itoh, Nobuo, Utiyama, Hiroyasu, Wahl, Geoffrey M.
Publicado 1998

RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses

por Toledo, Franck, Liu, Chung-Wen, Lee, Crystal J., Wahl, Geoffrey M.
Publicado 2006

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

por Trejo, Christy L., Luna, Gidsela, Dravis, Christopher, Spike, Benjamin T., Wahl, Geoffrey M.
Publicado 2017

Initiation of DNA replication at the human β-globin 3′ enhancer

por Buzina, Alla, Aladjem, Mirit I., Kolman, John L., Wahl, Geoffrey M., Ellis, James
Publicado 2005

Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling

por Bersini, Simone, Lytle, Nikki K, Schulte, Roberta, Huang, Ling, Wahl, Geoffrey M, Hetzer, Martin W
Publicado 2020

Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange

por Wong, Ee Tsin, Kolman, John L, Li, Yao-Cheng, Mesner, Larry D, Hillen, Wolfgang, Berens, Christian, Wahl, Geoffrey M
Publicado 2005

Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells

por Wade, Mark, Li, Yao-Cheng, Matani, Anand, Braun, Simon M G, Milanesi, Francesca, Rodewald, Luo Wei, Wahl, Geoffrey M
Publicado 2012

Use of a Molecular Genetic Platform Technology to Produce Human Wnt Proteins Reveals Distinct Local and Distal Signaling Abilities

por Green, Jennifer L., Bauer, Matthieu, Yum, Kyu Won, Li, Yao-Cheng, Cox, Miranda L., Willert, Karl, Wahl, Geoffrey M.
Publicado 2013

Linking the p53 tumor suppressor pathway to somatic cell reprogramming

por Kawamura, Teruhisa, Suzuki, Jotaro, Wang, Yunyuan V., Menendez, Sergio, Morera, Laura Batlle, Raya, Angel, Wahl, Geoffrey M., Belmonte, Juan Carlos Izpisúa
Publicado 2009

Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer

por Christin, John R., Wang, Chunhui, Chung, Chi-Yeh, Liu, Yu, Dravis, Christopher, Tang, Wei, Oktay, Maja H., Wahl, Geoffrey M., Guo, Wenjun
Publicado 2020

Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships

por Chung, Chi-Yeh, Ma, Zhibo, Dravis, Christopher, Preissl, Sebastian, Poirion, Olivier, Luna, Gidsela, Hou, Xiaomeng, Giraddi, Rajshekhar R., Ren, Bing, Wahl, Geoffrey M.
Publicado 2019

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

por DelGiorno, Kathleen E., Naeem, Razia F., Fang, Linjing, Chung, Chi-Yeh, Ramos, Cynthia, Luhtala, Natalie, O’Connor, Carolyn, Hunter, Tony, Manor, Uri, Wahl, Geoffrey M.
Publicado 2020

CRIPTO/GRP78 Signaling Maintains Fetal and Adult Mammary Stem Cells Ex Vivo

por Spike, Benjamin T., Kelber, Jonathan A., Booker, Evan, Kalathur, Madhuri, Rodewald, Rose, Lipianskaya, Julia, La, Justin, He, Marielle, Wright, Tracy, Klemke, Richard, Wahl, Geoffrey M., Gray, Peter C.
Publicado 2014

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

por Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Harrell, Joshua Chuck, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M
Publicado 2013

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy

por Saison-Ridinger, Maya, DelGiorno, Kathleen E., Zhang, Tejia, Kraus, Annabelle, French, Randall, Jaquish, Dawn, Tsui, Crystal, Erikson, Galina, Spike, Benjamin T., Shokhirev, Maxim N., Liddle, Christopher, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Saghatelian, Alan, Lowy, Andrew M., Wahl, Geoffrey M.
Publicado 2017

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

por Giraddi, Rajshekhar R., Chung, Chi-Yeh, Heinz, Richard E., Balcioglu, Ozlen, Novotny, Mark, Trejo, Christy L., Dravis, Christopher, Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Rodewald, Luo Wei, Hwang, Jae Y., Fan, Cheng, Lasken, Roger, Varley, Katherine E., Perou, Charles M., Wahl, Geoffrey M., Spike, Benjamin T.
Publicado 2018

Extrachromosomal oncogene amplification drives tumor evolution and genetic heterogeneity

por Turner, Kristen M., Deshpande, Viraj, Beyter, Doruk, Koga, Tomoyuki, Rusert, Jessica, Lee, Catherine, Li, Bin, Arden, Karen, Ren, Bing, Nathanson, David A., Kornblum, Harley I., Taylor, Michael D., Kaushal, Sharmeela, Cavenee, Webster K., Wechsler-Reya, Robert, Furnari, Frank B., Vandenberg, Scott R., Rao, P. Nagesh, Wahl, Geoffrey M., Bafna, Vineet, Mischel, Paul S.
Publicado 2017

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

por Sancho-Martinez, Ignacio, Nivet, Emmanuel, Xia, Yun, Hishida, Tomoaki, Aguirre, Aitor, Ocampo, Alejandro, Ma, Li, Morey, Robert, Krause, Marie N., Zembrzycki, Andreas, Ansorge, Olaf, Vazquez-Ferrer, Eric, Dubova, Ilir, Reddy, Pradeep, Lam, David, Hishida, Yuriko, Wu, Min-Zu, Esteban, Concepcion Rodriguez, O'Leary, Dennis, Wahl, Geoffrey M., Verma, Inder M., Laurent, Louise C., Izpisua Belmonte, Juan Carlos
Publicado 2016

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

por Shi, Yu, Gao, Weina, Lytle, Nikki K., Huang, Peiwu, Yuan, Xiao, Dann, Amanda M., Ridinger-Saison, Maya, DelGiorno, Kathleen E., Antal, Corina E., Liang, Gaoyang, Atkins, Annette R., Erikson, Galina, Sun, Huaiyu, Meisenhelder, Jill, Terenziani, Elena, Woo, Gyunghwi, Fang, Linjing, Santisakultarm, Thom P., Manor, Uri, Xu, Ruilian, Becerra, Carlos R., Borazanci, Erkut, Von Hoff, Daniel D., Grandgenett, Paul M., Hollingsworth, Michael A., Leblanc, Mathias, Umetsu, Sarah E., Collisson, Eric A., Scadeng, Miriam, Lowy, Andrew M., Donahue, Timothy R., Reya, Tannishtha, Downes, Michael, Evans, Ronald M., Wahl, Geoffrey M., Pawson, Tony, Tian, Ruijun, Hunter, Tony
Publicado 2019