Shared genetic risk factors: implications for treatment of idiopathic pulmonary fibrosis and systemic hypertension

por Parcesepe, Gina, Allen, Richard J., Guillen-Guio, Beatriz, Moss, Samuel, Jenkins, R. Gisli, Wain, Louise V.
Publicado 2023

Reply to Spek and Duitman

por Oldham, Justin M., Allen, Richard J., Lorenzo-Salazar, Jose M., Flores, Carlos, Wain, Louise V., Noth, Imre
Publicado 2023

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

por Melbourne, Carl A., Mesut Erzurumluoglu, A., Shrine, Nick, Chen, Jing, Tobin, Martin D., Hansell, Anna L., Wain, Louise V.
Publicado 2022

Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls

por Artigas, María Soler, Wain, Louise V., Shrine, Nick, McKeever, Tricia M., Sayers, Ian, Hall, Ian P., Tobin, Martin D.
Publicado 2017

Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

por Fawcett, Katherine A., Demidov, German, Shrine, Nick, Paynton, Megan L., Ossowski, Stephan, Sayers, Ian, Wain, Louise V., Hollox, Edward J.
Publicado 2022

Genetic overlap between idiopathic pulmonary fibrosis and COVID−19

por Allen, Richard J, Guillen-Guio, Beatriz, Croot, Emma, Kraven, Luke M, Moss, Samuel, Stewart, Iain, Jenkins, R Gisli, Wain, Louise V
Publicado 2022

Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity

por Fadista, João, Kraven, Luke M., Karjalainen, Juha, Andrews, Shea J., Geller, Frank, Baillie, J Kenneth, Wain, Louise V., Jenkins, R.Gisli, Feenstra, Bjarke
Publicado 2021

The Use of Genetic Information to Define Idiopathic Pulmonary Fibrosis in UK Biobank

por Leavy, Olivia C., Allen, Richard J., Kraven, Luke M., Morgan, Ann D., Tobin, Martin D., Quint, Jennifer K., Jenkins, R. Gisli, Wain, Louise V.
Publicado 2023

Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease

por Guyatt, Anna, John, Catherine, Williams, Alexander T, Shrine, Nick, Reeve, Nicola F, Sayers, Ian, Hall, Ian, Wain, Louise V, Sheehan, Nuala, Dudbridge, Frank, Tobin, Martin D
Publicado 2023

The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci

por Wain, Louise V., Pedroso, Inti, Landers, John E., Breen, Gerome, Shaw, Christopher E., Leigh, P. Nigel, Brown, Robert H., Tobin, Martin D., Al-Chalabi, Ammar
Publicado 2009

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function

por Adewoye, Adeolu B., Shrine, Nick, Odenthal-Hesse, Linda, Welsh, Samantha, Malarstig, Anders, Jelinsky, Scott, Kilty, Iain, Tobin, Martin D., Hollox, Edward J., Wain, Louise V.
Publicado 2018

Adjustment for index event bias in genome-wide association studies of subsequent events

por Dudbridge, Frank, Allen, Richard J., Sheehan, Nuala A., Schmidt, A. Floriaan, Lee, James C., Jenkins, R. Gisli, Wain, Louise V., Hingorani, Aroon D., Patel, Riyaz S.
Publicado 2019

Mapping brain endophenotypes associated with idiopathic pulmonary fibrosis genetic risk

por Mohammadi-Nejad, Ali-Reza, Allen, Richard J., Kraven, Luke M., Leavy, Olivia C., Jenkins, R. Gisli, Wain, Louise V., Auer, Dorothee P., Sotiropoulos, Stamatios N.
Publicado 2022

Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

por Kerr, Shona M, Campbell, Archie, Murphy, Lee, Hayward, Caroline, Jackson, Cathy, Wain, Louise V, Tobin, Martin D, Dominiczak, Anna, Morris, Andrew, Smith, Blair H, Porteous, David J
Publicado 2013

The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis

por Miller, Suzanne, Coveney, Clare, Johnson, Janice, Farmaki, Aliki-Eleni, Gupta, Nishant, Tobin, Martin D., Wain, Louise V., McCormack, Francis X., Boocock, David J., Johnson, Simon R.
Publicado 2018

A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases

por Liu, Wei, Deng, Wenxuan, Chen, Ming, Dong, Zihan, Zhu, Biqing, Yu, Zhaolong, Tang, Daiwei, Sauler, Maor, Lin, Chen, Wain, Louise V., Cho, Michael H., Kaminski, Naftali, Zhao, Hongyu
Publicado 2023

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations

por Leavy, Olivia C., Ma, Shwu-Fan, Molyneaux, Philip L., Maher, Toby M., Oldham, Justin M., Flores, Carlos, Noth, Imre, Jenkins, R. Gisli, Dudbridge, Frank, Wain, Louise V., Allen, Richard J.
Publicado 2021

Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment

por Wielscher, Matthias, Amaral, Andre F. S., van der Plaat, Diana, Wain, Louise V., Sebert, Sylvain, Mosen-Ansorena, David, Auvinen, Juha, Herzig, Karl-Heinz, Dehghan, Abbas, Jarvis, Debbie L., Jarvelin, Marjo-Riitta
Publicado 2021

Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing

por Lorenzo-Salazar, Jose M., Ma, Shwu-Fan, Jou, Jonathan, Hou, Pei-Chi, Guillen-Guio, Beatriz, Allen, Richard J., Jenkins, R. Gisli, Wain, Louise V., Oldham, Justin M., Noth, Imre, Flores, Carlos
Publicado 2019

Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

por Fabbri, Chiara, Hagenaars, Saskia P., John, Catherine, Williams, Alexander T., Shrine, Nick, Moles, Louise, Hanscombe, Ken B., Serretti, Alessandro, Shepherd, David J., Free, Robert C., Wain, Louise V., Tobin, Martin D., Lewis, Cathryn M.
Publicado 2021