A high-content platform for physiological profiling and unbiased classification of individual neurons

por DuBreuil, Daniel M., Chiang, Brenda M., Zhu, Kevin, Lai, Xiaofan, Flynn, Patrick, Sapir, Yechiam, Wainger, Brian J.
Publicado 2021

Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons

por Moakley, Daniel, Koh, Joan, Pereira, Joao D., DuBreuil, Daniel M., Devlin, Anna-Claire, Berezovski, Eugene, Zhu, Kevin, Wainger, Brian J.
Publicado 2019

Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic

por DuBreuil, Daniel M, Lai, Xiaofan, Zhu, Kevin, Chahyadinata, Gracesenia, Perner, Caroline, Chiang, Brenda M, Battenberg, Ashley, Sokol, Caroline L, Wainger, Brian J
Publicado 2023

Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions

por Pereira, João D., DuBreuil, Daniel M., Devlin, Anna-Claire, Held, Aaron, Sapir, Yechiam, Berezovski, Eugene, Hawrot, James, Dorfman, Katherine, Chander, Vignesh, Wainger, Brian J.
Publicado 2021

iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons

por Held, Aaron, Adler, Michelle, Marques, Christine, Reyes, Charles Jourdan, Kavuturu, Amey S., Quadros, Ana R.A.A., Ndayambaje, I. Sandra, Lara, Erika, Ward, Michael, Lagier-Tourenne, Clotilde, Wainger, Brian J.
Publicado 2023

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

por Wainger, Brian J., Buttermore, Elizabeth D., Oliveira, Julia T., Mellin, Cassidy, Lee, Seungkyu, Saber, Wardiya Afshar, Wang, Amy, Ichida, Justin K., Chiu, Isaac M., Barrett, Lee, Huebner, Eric A., Bilgin, Canan, Tsujimoto, Naomi, Brenneis, Christian, Kapur, Kush, Rubin, Lee L., Eggan, Kevin, Woolf, Clifford J.
Publicado 2014

ALS IMPLICATED PROTEIN TDP-43 SUSTAINS LEVELS OF STMN2 A MEDIATOR OF MOTOR NEURON GROWTH AND REPAIR

por Klim, Joseph R., Williams, Luis A., Limone, Francesco, Juan, Irune Guerra San, Davis-Dusenbery, Brandi N., Mordes, Daniel A., Burberry, Aaron, Steinbaugh, Michael J., Gamage, Kanchana K., Kirchner, Rory, Moccia, Rob, Cassel, Seth H., Chen, Kuchuan, Wainger, Brian J., Woolf, Clifford J., Eggan, Kevin
Publicado 2019

Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke

por Li, Wenlu, Mandeville, Emiri T., Durán-Laforet, Violeta, Fukuda, Norito, Yu, Zhanyang, Zheng, Yi, Held, Aaron, Park, Ji-Hyun, Nakano, Takafumi, Tanaka, Masayoshi, Shi, Jingfei, Esposito, Elga, Niu, Wanting, Xing, Changhong, Hayakawa, Kazuhide, Lizasoain, Ignacio, van Leyen, Klaus, Ji, Xunming, Wainger, Brian J., Moro, Maria A., Lo, Eng H.
Publicado 2022

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease

por Jambeau, Melanie, Meyer, Kevin D., Hruska-Plochan, Marian, Tabet, Ricardos, Lee, Chao-Zong, Ray-Soni, Ananya, Aguilar, Corey, Savage, Kitty, Mishra, Nibha, Cavegn, Nicole, Borter, Petra, Lin, Chun-Chia, Jansen-West, Karen R., Jiang, Jie, Freyermuth, Fernande, Li, Nan, De Rossi, Pierre, Pérez-Berlanga, Manuela, Jiang, Xin, Daughrity, Lilian M., Pereira, João, Narayanan, Sarav, Gu, Yuanzheng, Dhokai, Shekhar, Dalkilic-Liddle, Isin, Maniecka, Zuzanna, Weber, Julien, Workman, Michael, McAlonis-Downes, Melissa, Berezovski, Eugene, Zhang, Yong-Jie, Berry, James, Wainger, Brian J., Kankel, Mark W., Rushe, Mia, Hock, Christoph, Nitsch, Roger M., Cleveland, Don W., Petrucelli, Leonard, Gendron, Tania F., Montrasio, Fabio, Grimm, Jan, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde
Publicado 2022