Transforming growth factor-β and breast cancer: Lessons learned from genetically altered mouse models

por Wakefield, Lalage M, Yang, Yu-an, Dukhanina, Oksana
Publicado 2000

Regulation of Tumor Immune Surveillance and Tumor Immune Subversion by TGF-β

por Park, Hae-Young, Wakefield, Lalage M, Mamura, Mizuko
Publicado 2009

Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide

por Chen, Xin, Wakefield, Lalage M, Oppenheim, Joost J
Publicado 2014

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics

por Chen, Jin-Qiu, Wakefield, Lalage M, Goldstein, David J
Publicado 2015

Transforming growth factors-β are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system

por Zujewski, JoAnne, Vaughn-Cooke, Anika, Flanders, Kathleen C, Eckhaus, Michael A, Lubet, Ronald A, Wakefield, Lalage M
Publicado 2001

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

por Flanders, Kathleen C., Yang, Yu-an, Herrmann, Michelle, Chen, JinQiu, Mendoza, Nerissa, Mirza, Amer M., Wakefield, Lalage M.
Publicado 2016

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model

por Sato, Misako, Matsubara, Tsutomu, Adachi, Jun, Hashimoto, Yuuki, Fukamizu, Kazuna, Kishida, Marina, Yang, Yu-an, Wakefield, Lalage M., Tomonaga, Takeshi
Publicado 2015

Genetic Background May Contribute to PAM50 Gene Expression Breast Cancer Subtype Assignments

por Hu, Ying, Bai, Ling, Geiger, Thomas, Goldberger, Natalie, Walker, Renard C., Green, Jeffery E., Wakefield, Lalage M., Hunter, Kent W.
Publicado 2013

Expression of the B-Cell Receptor Component CD79a on Immature Myeloid Cells Contributes to Their Tumor Promoting Effects

por Luger, Dror, Yang, Yu-an, Raviv, Asaf, Weinberg, Douglas, Banerjee, Subhadra, Lee, Min-Jung, Trepel, Jane, Yang, Li, Wakefield, Lalage M.
Publicado 2013

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines

por Kadota, Mitsutaka, Yang, Howard H., Gomez, Bianca, Sato, Misako, Clifford, Robert J., Meerzaman, Daoud, Dunn, Barbara K., Wakefield, Lalage M., Lee, Maxwell P.
Publicado 2010

Effective Chemoimmunotherapy with Anti-TGFβ Antibody and Cyclophosphamide in a Mouse Model of Breast Cancer

por Chen, Xin, Yang, Yuan, Zhou, Qiong, Weiss, Jonathan M., Howard, OlaMae Zack, McPherson, John M., Wakefield, Lalage M., Oppenheim, Joost J.
Publicado 2014

Disruption of Transforming Growth Factor β Signaling by a Novel Ligand-dependent Mechanism

por Fernandez, Tania, Amoroso, Stephanie, Sharpe, Shellyann, Jones, Gary M., Bliskovski, Valery, Kovalchuk, Alexander, Wakefield, Lalage M., Kim, Seong-Jin, Potter, Michael, Letterio, John J.
Publicado 2002

Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor-β/Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections

por Flanders, Kathleen C., Heger, Christopher D., Conway, Catherine, Tang, Binwu, Sato, Misako, Dengler, Samuel L., Goldsmith, Paul K., Hewitt, Stephen M., Wakefield, Lalage M.
Publicado 2014

Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer

por Stuelten, Christina H., Busch, Johanna I., Tang, Binwu, Flanders, Kathleen C., Oshima, Akira, Sutton, Emily, Karpova, Tatiana S., Roberts, Anita B., Wakefield, Lalage M., Niederhuber, John E.
Publicado 2010

SDF-1α Mediates Wound-Promoted Tumor Growth in a Syngeneic Orthotopic Mouse Model of Breast Cancer

por Stuelten, Christina H., Cervoni-Curet, Frances N., Busch, Johanna I., Sutton, Emily, Webster, Joshua D., Kavalukas, Sandra L., Wakefield, Lalage M., Barbul, Adrian, Niederhuber, John E.
Publicado 2013

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland

por Kohn, Ethan A, Du, Zhijun, Sato, Misako, Van Schyndle, Catherine MH, Welsh, Michael A, Yang, Yu-an, Stuelten, Christina H, Tang, Binwu, Ju, Wenjun, Bottinger, Erwin P, Wakefield, Lalage M
Publicado 2010

Selective targeting of KRAS-Mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-Mutant cells

por Hara, Toshifumi, Jones, Matthew F., Subramanian, Murugan, Li, Xiao Ling, Ou, Oliver, Zhu, Yuelin, Yang, Yuan, Wakefield, Lalage M., Hussain, S. Perwez, Gaedcke, Jochen, Ried, Thomas, Luo, Ji, Caplen, Natasha J., Lal, Ashish
Publicado 2014

A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

por Tang, Binwu, Raviv, Asaf, Esposito, Dominic, Flanders, Kathleen C., Daniel, Catherine, Nghiem, Bao Tram, Garfield, Susan, Lim, Langston, Mannan, Poonam, Robles, Ana I., Smith, William I., Zimmerberg, Joshua, Ravin, Rea, Wakefield, Lalage M.
Publicado 2014

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer

por Sato, Misako, Kadota, Mitsutaka, Tang, Binwu, Yang, Howard H, Yang, Yu-an, Shan, Mengge, Weng, Jia, Welsh, Michael A, Flanders, Kathleen C, Nagano, Yoshiko, Michalowski, Aleksandra M, Clifford, Robert J, Lee, Maxwell P, Wakefield, Lalage M
Publicado 2014

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis

por Yang, Yuan, Yang, Howard H., Hu, Ying, Watson, Peter H., Liu, Huaitian, Geiger, Thomas R., Anver, Miriam R., Haines, Diana C., Martin, Philip, Green, Jeffrey E., Lee, Maxwell P., Hunter, Kent W., Wakefield, Lalage M.
Publicado 2017