Histone deacetylase inhibitors enhance oncolytic herpes simplex virus therapy for malignant meningioma

por Kawamura, Yoichiro, Hua, Lingyang, Gurtner, Alessandra, Wong, Ego, Kiyokawa, Juri, Shah, Nadia, Gorham, Joshua, Wakimoto, Hiroko, Rabkin, Samuel D., Martuza, Robert L., Wakimoto, Hiroaki
Publicado 2022

Slow progressive conduction and contraction defects in loss of Nkx2–5 mice after cardiomyocyte terminal differentiation

por Takeda, Morihiko, Briggs, Laura E., Wakimoto, Hiroko, Marks, Melissa H., Warren, Sonisha A., Lu, Jonathan T., Weinberg, Ellen O., Robertson, Keith D., Chien, Kenneth R., Kasahara, Hideko
Publicado 2009

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

por Ning, Jian-Fang, Stanciu, Monica, Humphrey, Melissa R., Gorham, Joshua, Wakimoto, Hiroko, Nishihara, Reiko, Lees, Jacqueline, Zou, Lee, Martuza, Robert L., Wakimoto, Hiroaki, Rabkin, Samuel D.
Publicado 2019

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

por Onoue, Kenji, Wakimoto, Hiroko, Jiang, Jiangming, Parfenov, Michael, DePalma, Steven, Conner, David, Gorham, Joshua, McKean, David, Seidman, Jonathan G., Seidman, Christine E., Saito, Yoshihiko
Publicado 2021

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

por Bick, Alexander G., Wakimoto, Hiroko, Kamer, Kimberli J., Sancak, Yasemin, Goldberger, Olga, Axelsson, Anna, DeLaughter, Daniel M., Gorham, Joshua M., Mootha, Vamsi K., Seidman, J. G., Seidman, Christine E.
Publicado 2017

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

por Alcalai, Ronny, Arad, Michael, Wakimoto, Hiroko, Yadin, Dor, Gorham, Joshua, Wang, Libin, Burns, Elia, Maron, Barry J., Roberts, William C., Konno, Tetsuo, Conner, David A., Perez‐Atayde, Antonio R., Seidman, Jon G., Seidman, Christine E.
Publicado 2021

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere

por Agarwal, Radhika, Wakimoto, Hiroko, Paulo, Joao A., Zhang, Qi, Reichart, Daniel, Toepfer, Christopher, Sharma, Arun, Tai, Angela C., Lun, Mingyue, Gorham, Joshua, DePalma, Steven R., Gygi, Steven P., Seidman, J.G., Seidman, Christine E.
Publicado 2022

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

por Reichart, Daniel, Newby, Gregory A., Wakimoto, Hiroko, Lun, Mingyue, Gorham, Joshua M., Curran, Justin J., Raguram, Aditya, DeLaughter, Daniel M., Conner, David A., Marsiglia, Júlia D. C., Kohli, Sajeev, Chmatal, Lukas, Page, David C., Zabaleta, Nerea, Vandenberghe, Luk, Liu, David R., Seidman, Jonathan G., Seidman, Christine
Publicado 2023

Dissecting spatio-temporal protein networks driving human heart development and related disorders

por Lage, Kasper, Møllgård, Kjeld, Greenway, Steven, Wakimoto, Hiroko, Gorham, Joshua M, Workman, Christopher T, Bendsen, Eske, Hansen, Niclas T, Rigina, Olga, Roque, Francisco S, Wiese, Cornelia, Christoffels, Vincent M, Roberts, Amy E, Smoot, Leslie B, Pu, William T, Donahoe, Patricia K, Tommerup, Niels, Brunak, Søren, Seidman, Christine E, Seidman, Jonathan G, Larsen, Lars A
Publicado 2010

Loss of RNA expression and allele-specific expression associated with congenital heart disease

por McKean, David M., Homsy, Jason, Wakimoto, Hiroko, Patel, Neil, Gorham, Joshua, DePalma, Steven R., Ware, James S., Zaidi, Samir, Ma, Wenji, Patel, Nihir, Lifton, Richard P., Chung, Wendy K., Kim, Richard, Shen, Yufeng, Brueckner, Martina, Goldmuntz, Elizabeth, Sharp, Andrew J., Seidman, Christine E., Gelb, Bruce D., Seidman, J. G.
Publicado 2016

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

por Axelsson Raja, Anna, Wakimoto, Hiroko, DeLaughter, Daniel M., Reichart, Daniel, Gorham, Joshua, Conner, David A., Lun, Mingyue, Probst, Clemens K., Sakai, Norihiko, Knipe, Rachel S., Montesi, Sydney B., Shea, Barry, Adam, Leonard P., Leinwand, Leslie A., Wan, William, Choi, Esther Sue, Lindberg, Eric L., Patone, Giannino, Noseda, Michela, Hübner, Norbert, Seidman, Christine E., Tager, Andrew M., Seidman, J. G., Ho, Carolyn Y.
Publicado 2022

A Broad Phenotypic Screen Identifies Novel Phenotypes Driven by a Single Mutant Allele in Huntington’s Disease CAG Knock-In Mice

por Hölter, Sabine M., Stromberg, Mary, Kovalenko, Marina, Garrett, Lillian, Glasl, Lisa, Lopez, Edith, Guide, Jolene, Götz, Alexander, Hans, Wolfgang, Becker, Lore, Rathkolb, Birgit, Rozman, Jan, Schrewed, Anja, Klingenspor, Martin, Klopstock, Thomas, Schulz, Holger, Wolf, Eckhard, Wursta, Wolfgang, Gillis, Tammy, Wakimoto, Hiroko, Seidman, Jonathan, MacDonald, Marcy E., Cotman, Susan, Gailus-Durner, Valérie, Fuchs, Helmut, de Angelis, Martin Hrabě, Lee, Jong-Min, Wheeler, Vanessa C.
Publicado 2013

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

por Toepfer, Christopher N., Garfinkel, Amanda C., Venturini, Gabriela, Wakimoto, Hiroko, Repetti, Giuliana, Alamo, Lorenzo, Sharma, Arun, Agarwal, Radhika, Ewoldt, Jourdan F., Cloonan, Paige, Letendre, Justin, Lun, Mingyue, Olivotto, Iacopo, Colan, Steve, Ashley, Euan, Jacoby, Daniel, Michels, Michelle, Redwood, Charles S., Watkins, Hugh C., Day, Sharlene M., Staples, James F., Padrón, Raúl, Chopra, Anant, Ho, Carolyn Y., Chen, Christopher S., Pereira, Alexandre C., Seidman, Jonathan G., Seidman, Christine E.
Publicado 2020

Cells of the adult human heart

por Litviňuková, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Worth, Catherine L., Lindberg, Eric L., Kanda, Masatoshi, Polanski, Krzysztof, Heinig, Matthias, Lee, Michael, Nadelmann, Emily R., Roberts, Kenny, Tuck, Liz, Fasouli, Eirini S., DeLaughter, Daniel M., McDonough, Barbara, Wakimoto, Hiroko, Gorham, Joshua M., Samari, Sara, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Patone, Giannino, Boyle, Joseph J., Zhang, Hongbo, Zhang, Hao, Viveiros, Anissa, Oudit, Gavin Y., Bayraktar, Omer Ali, Seidman, J. G., Seidman, Christine E., Noseda, Michela, Hubner, Norbert, Teichmann, Sarah A.
Publicado 2020

De novo mutations in histone modifying genes in congenital heart disease

por Zaidi, Samir, Choi, Murim, Wakimoto, Hiroko, Ma, Lijiang, Jiang, Jianming, Overton, John D., Romano-Adesman, Angela, Bjornson, Robert D., Breitbart, Roger E., Brown, Kerry K., Carriero, Nicholas J., Cheung, Yee Him, Deanfield, John, DePalma, Steve, Fakhro, Khalid A., Glessner, Joseph, Hakonarson, Hakon, Italia, Michael, Kaltman, Jonathan R., Kaski, Juan, Kim, Richard, Kline, Jennie K., Lee, Teresa, Leipzig, Jeremy, Lopez, Alexander, Mane, Shrikant M., Mitchell, Laura E., Newburger, Jane W., Parfenov, Michael, Pe'er, Itsik, Porter, George, Roberts, Amy, Sachidanandam, Ravi, Sanders, Stephan J., Seiden, Howard S., State, Mathew W., Subramanian, Sailakshmi, Tikhonova, Irina R., Wang, Wei, Warburton, Dorothy, White, Peter S., Williams, Ismee A., Zhao, Hongyu, Seidman, Jonathan G., Brueckner, Martina, Chung, Wendy K., Gelb, Bruce D., Goldmuntz, Elizabeth, Seidman, Christine E., Lifton, Richard P.
Publicado 2013

Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy

por Garcia-Pavia, Pablo, Kim, Yuri, Restrepo-Cordoba, Maria Alejandra, Lunde, Ida G., Wakimoto, Hiroko, Smith, Amanda M., Toepfer, Christopher N., Getz, Kelly, Gorham, Joshua, Patel, Parth, Ito, Kaoru, Willcox, Jonathan A., Arany, Zoltan, Li, Jian, Owens, Anjali T., Govind, Risha, Nuñez, Beatriz, Mazaika, Erica, Bayes-Genis, Antoni, Walsh, Roddy, Finkelman, Brian, Lupon, Josep, Whiffin, Nicola, Serrano, Isabel, Midwinter, William, Wilk, Alicja, Bardaji, Alfredo, Ingold, Nathan, Buchan, Rachel, Tayal, Upasana, Pascual-Figal, Domingo A., de Marvao, Antonio, Ahmad, Mian, Garcia-Pinilla, Jose Manuel, Pantazis, Antonis, Dominguez, Fernando, John Baksi, A., O’Regan, Declan P., Rosen, Stuart D., Prasad, Sanjay K., Lara-Pezzi, Enrique, Provencio, Mariano, Lyon, Alexander R., Alonso-Pulpon, Luis, Cook, Stuart A., DePalma, Steven R., Barton, Paul J.R., Aplenc, Richard, Seidman, Jonathan G., Ky, Bonnie, Ware, James S., Seidman, Christine E.
Publicado 2019

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

por Reichart, Daniel, Lindberg, Eric L., Maatz, Henrike, Miranda, Antonio M.A., Viveiros, Anissa, Shvetsov, Nikolay, Gärtner, Anna, Nadelmann, Emily R., Lee, Michael, Kanemaru, Kazumasa, Ruiz-Orera, Jorge, Strohmenger, Viktoria, DeLaughter, Daniel M., Patone, Giannino, Zhang, Hao, Woehler, Andrew, Lippert, Christoph, Kim, Yuri, Adami, Eleonora, Gorham, Joshua M., Barnett, Sam N., Brown, Kemar, Buchan, Rachel J., Chowdhury, Rasheda A., Constantinou, Chrystalla, Cranley, James, Felkin, Leanne E., Fox, Henrik, Ghauri, Ahla, Gummert, Jan, Kanda, Masatoshi, Li, Ruoyan, Mach, Lukas, McDonough, Barbara, Samari, Sara, Shahriaran, Farnoush, Yapp, Clarence, Stanasiuk, Caroline, Theotokis, Pantazis I., Theis, Fabian J., van den Bogaerdt, Antoon, Wakimoto, Hiroko, Ware, James S., Worth, Catherine L., Barton, Paul J.R., Lee, Young-Ae, Teichmann, Sarah A., Milting, Hendrik, Noseda, Michela, Oudit, Gavin Y., Heinig, Matthias, Seidman, Jonathan G., Hubner, Norbert, Seidman, Christine E.
Publicado 2022