On the Necessity and Importance of the Accoucheur's Profession

por Wales, Thomas
Publicado 1818

Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

por Cohen, Daniel T., Wales, Thomas E., McHenry, Matthew W., Engen, John R., Walensky, Loren D.
Publicado 2020

A redox switch regulates the structure and function of anti-apoptotic BFL-1

por Korshavn, Kyle J., Wales, Thomas E., Bird, Gregory H., Engen, John R., Walensky, Loren D.
Publicado 2020

Differential impact of BTK active site inhibitors on the conformational state of full-length BTK

por Joseph, Raji E, Amatya, Neha, Fulton, D Bruce, Engen, John R, Wales, Thomas E, Andreotti, Amy
Publicado 2020

The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core

por Bloch, Noah B., Wales, Thomas E., Prew, Michelle S., Levy, Hannah R., Engen, John R., Walensky, Loren D.
Publicado 2021

Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement

por Moroco, Jamie A., Craigo, Jodi K., Iacob, Roxana E., Wales, Thomas E., Engen, John R., Smithgall, Thomas E.
Publicado 2014

Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

por Chopra, Nikita, Wales, Thomas E., Joseph, Raji E., Boyken, Scott E., Engen, John R., Jernigan, Robert L., Andreotti, Amy H.
Publicado 2016

Design of Stapled Antimicrobial Peptides that Overcome Antibiotic Resistance and In Vivo Toxicity

por Mourtada, Rida, Herce, Henry D., Yin, Daniel J., Moroco, Jamie A., Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2019

Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4

por Bodnar, Nicholas O., Kim, Kelly H., Ji, Zhejian, Wales, Thomas E., Svetlov, Vladimir, Nudler, Evgeny, Engen, John R., Walz, Thomas, Rapoport, Tom A.
Publicado 2018

Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases

por Amatya, Neha, Wales, Thomas E., Kwon, Annie, Yeung, Wayland, Joseph, Raji E., Fulton, D. Bruce, Kannan, Natarajan, Engen, John R., Andreotti, Amy H.
Publicado 2019

HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck

por Pene-Dumitrescu, Teodora, Shu, Sherry T, Wales, Thomas E, Alvarado, John J, Shi, Haibin, Narute, Purushottam, Moroco, Jamie A, Yeh, Joanne I, Engen, John R, Smithgall, Thomas E
Publicado 2012

Allosteric Inhibition of Anti-Apoptotic MCL-1

por Lee, Susan, Wales, Thomas E., Escudero, Silvia, Cohen, Daniel T., Luccarelli, James, Gallagher, Catherine, Cohen, Nicole A., Huhn, Annissa J., Bird, Gregory H., Engen, John R., Walensky, Loren D.
Publicado 2016

Allosteric Sensitization of Pro-Apoptotic BAX

por Pritz, Jonathan R., Wachter, Franziska, Lee, Susan, Luccarelli, James, Wales, Thomas E., Cohen, Daniel T., Coote, Paul W., Heffron, Gregory J., Engen, John R., Massefski, Walter, Walensky, Loren D.
Publicado 2017

Targeting a Helix-in-Groove Interaction Between E1 and E2 Blocks Ubiquitin Transfer

por Cathcart, Ann M., Bird, Gregory H., Wales, Thomas E., Herce, Henry D., Harvey, Edward P., Hauseman, Zachary J., Newman, Catherine E., Adhikary, Utsarga, Prew, Michelle S., Oo, Tun, Lee, Susan, Engen, John R., Walensky, Loren D.
Publicado 2020

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

por Prew, Michelle S., Camara, Christina M., Botzanowski, Thomas, Moroco, Jamie A., Bloch, Noah B., Levy, Hannah R., Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Bird, Gregory H., Herce, Henry D., Gygi, Micah A., Escudero, Silvia, Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2022

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

por Masson, Glenn R., Burke, John E., Ahn, Natalie G., Anand, Ganesh S., Borchers, Christoph, Brier, Sébastien, Bou-Assaf, George M., Engen, John R., Englander, S. Walter, Faber, Johan, Garlish, Rachel, Griffin, Patrick R., Gross, Michael L., Guttman, Miklos, Hamuro, Yoshitomo, Heck, Albert J. R., Houde, Damian, Iacob, Roxana E., Jørgensen, Thomas J. D., Kaltashov, Igor A., Klinman, Judith P., Konermann, Lars, Man, Petr, Mayne, Leland, Pascal, Bruce D., Reichmann, Dana, Skehel, Mark, Snijder, Joost, Strutzenberg, Timothy S., Underbakke, Eric S., Wagner, Cornelia, Wales, Thomas E., Walters, Benjamin T., Weis, David D., Wilson, Derek J., Wintrode, Patrick L., Zhang, Zhongqi, Zheng, Jie, Schriemer, David C., Rand, Kasper D.
Publicado 2019