Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation

por Baumhardt, Jordan M., Walker, Janek S., Lee, Yoonji, Shakya, Binita, Brautigam, Chad A., Lapalombella, Rosa, Grishin, Nick, Chook, Yuh Min
Publicado 2020

Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions

por Zhang, Pu, Brinton, Lindsey T., Gharghabi, Mehdi, Sher, Steven, Williams, Katie, Cannon, Matthew, Walker, Janek S., Canfield, Daniel, Beaver, Larry, Cempre, Casey B., Phillips, Hannah, Chen, Xuyong, Yan, Pearlly, Lehman, Amy, Scherle, Peggy, Wang, Min, Vaddi, Kris, Baiocchi, Robert, Wang, Ruoning, Sampath, Deepa, Alinari, Lapo, Blachly, James S., Lapalombella, Rosa
Publicado 2022

VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia

por Sher, Steven, Whipp, Ethan, Walker, Janek, Zhang, Pu, Beaver, Larry, Williams, Katie, Orwick, Shelley, Ravikrishnan, Janani, Walker, Brandi, Perry, Elizabeth, Gregory, Charles, Purcell, Matthew, Pan, Alexander, Yan, Pearlly, Alinari, Lapo, Johnson, Amy J., Frigault, Melanie M., Greer, Joy M., Hamdy, Ahmed, Izumi, Raquel, Mo, Xiaokui, Sampath, Deepa, Woyach, Jennifer, Blachly, James, Byrd, John C., Lapalombella, Rosa
Publicado 2022

Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia

por Walker, Janek S., Hing, Zachary A., Sher, Steven, Cronin, James, Williams, Katie, Harrington, Bonnie, Skinner, Jordan N., Cempre, Casey B., Gregory, Charles T., Pan, Alexander, Yano, Max, Beaver, Larry P., Walker, Brandi R., Labanowska, Jadwiga M., Heerema, Nyla A., Mrózek, Krzysztof, Woyach, Jennifer A., Ruppert, Amy S., Lehman, Amy, Ozer, Hatice Gulcin, Coppola, Vincenzo, Yan, Pearlly, Byrd, John C., Blachly, James S., Lapalombella, Rosa
Publicado 2021

Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia

por Walker, Janek S., Hing, Zachary A., Harrington, Bonnie, Baumhardt, Jordan, Ozer, Hatice Gulcin, Lehman, Amy, Giacopelli, Brian, Beaver, Larry, Williams, Katie, Skinner, Jordan N., Cempre, Casey B., Sun, Qingxiang, Shacham, Sharon, Stromberg, Benjamin R., Summers, Matthew K., Abruzzo, Lynne V., Rassenti, Laura, Kipps, Thomas J., Parikh, Sameer, Kay, Neil E., Rogers, Kerry A., Woyach, Jennifer A., Coppola, Vincenzo, Chook, Yuh Min, Oakes, Christopher, Byrd, John C., Lapalombella, Rosa
Publicado 2021

Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation

por Hing, Zachary A., Walker, Janek S., Whipp, Ethan C., Brinton, Lindsey, Cannon, Matthew, Zhang, Pu, Sher, Steven, Cempre, Casey B., Brown, Fiona, Smith, Porsha L., Agostinelli, Claudio, Pileri, Stefano A., Skinner, Jordan N., Williams, Katie, Phillips, Hannah, Shaffer, Jami, Beaver, Larry P., Pan, Alexander, Shin, Kyle, Gregory, Charles T., Ozer, Gulcin H., Yilmaz, Selen A., Harrington, Bonnie K., Lehman, Amy M., Yu, Lianbo, Coppola, Vincenzo, Yan, Pearlly, Scherle, Peggy, Wang, Min, Pitis, Philip, Xu, Chaoyi, Vaddi, Kris, Chen-Kiang, Selina, Woyach, Jennifer, Blachly, James S., Alinari, Lapo, Yang, Yiping, Byrd, John C., Baiocchi, Robert A., Blaser, Bradley W., Lapalombella, Rosa
Publicado 2023