Passive immunotherapy of viral infections: 'super-antibodies' enter the fray

por Walker, Laura M., Burton, Dennis R.
Publicado 2018

Rational Vaccine Design in the Time of COVID-19

por Burton, Dennis R., Walker, Laura M.
Publicado 2020

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data

por Ferguson, Andrew L., Falkowska, Emilia, Walker, Laura M., Seaman, Michael S., Burton, Dennis R., Chakraborty, Arup K.
Publicado 2013

Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes

por Huang, Ching-Yu, Sharma, Girdhar G., Walker, Laura M., Bassing, Craig H., Pandita, Tej K., Sleckman, Barry P.
Publicado 2007

1089. Use of a Whole-Body Quantitative System Pharmacology Physiologically-Based Pharmacokinetic (QSP/PBPK) Model to Support Dose Selection of ADG20: an Extended Half-Life Monoclon...

por Van Wart, Scott A, Tarbell, Evan D, Narayan, Kristin, Walker, Laura M, Connolly, Lynn E, Ambrose, Paul G
Publicado 2021

Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies

por Temme, J. Sebastian, Crainic, Jennifer A., Walker, Laura M., Yang, Weizhun, Tan, Zibin, Huang, Xuefei, Gildersleeve, Jeffrey C.
Publicado 2022

Recall of pre-existing cross-reactive B cell memory following Omicron BA.1 breakthrough infection

por Kaku, Chengzi I., Bergeron, Alan J., Ahlm, Clas, Normark, Johan, Sakharkar, Mrunal, Forsell, Mattias N. E., Walker, Laura M.
Publicado 2022

Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

por Shehata, Laila, Wieland-Alter, Wendy F., Maurer, Daniel P., Chen, Eunice, Connor, Ruth I., Wright, Peter F., Walker, Laura M.
Publicado 2019

Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron

por Liu, Hejun, Kaku, Chengzi I., Song, Ge, Yuan, Meng, Andrabi, Raiees, Burton, Dennis R., Walker, Laura M., Wilson, Ian A.
Publicado 2022

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

por Walker, Laura M., Simek, Melissa D., Priddy, Frances, Gach, Johannes S., Wagner, Denise, Zwick, Michael B., Phogat, Sanjay K., Poignard, Pascal, Burton, Dennis R.
Publicado 2010

1088. A Whole-Body Quantitative System Pharmacology Physiologically-Based Pharmacokinetic (QSP/PBPK) Model to Support Dose Selection of ADG20: an Extended Half-Life Monoclonal Anti...

por Tarbell, Evan D, Van Wart, Scott A, Shah, Dhaval K, Walker, Laura M, Santulli, Andrew, Connolly, Lynn E, Mager, Donald E, Brown, Ashley N, Ambrose, Paul G
Publicado 2021

H2AX Prevents CtIP-Mediated DNA End Resection and Aberrant Repair in G1-Phase Lymphocytes

por Helmink, Beth A., Tubbs, Anthony T., Dorsett, Yair, Bednarski, Jeffrey J., Walker, Laura M., Feng, Zhihui, Sharma, Girdhar, McKinnon, Peter J., Zhang, Junran, Bassing, Craig H., Sleckman, Barry P.
Publicado 2010

Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination

por Kaku, Chengzi I., Champney, Elizabeth R., Normark, Johan, Garcia, Marina, Johnson, Carl E., Ahlm, Clas, Christ, Wanda, Sakharkar, Mrunal, Ackerman, Margaret E., Klingström, Jonas, Forsell, Mattias N. E., Walker, Laura M.
Publicado 2022

Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections

por Sevvana, Madhumati, Rogers, Thomas F., Miller, Andrew S., Long, Feng, Klose, Thomas, Beutler, Nathan, Lai, Yen-Chung, Parren, Mara, Walker, Laura M., Buda, Geeta, Burton, Dennis R., Rossmann, Michael G., Kuhn, Richard J.
Publicado 2020

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

por Helmink, Beth A., Bredemeyer, Andrea L., Lee, Baeck-Seung, Huang, Ching-Yu, Sharma, Girdhar G., Walker, Laura M., Bednarski, Jeffrey J., Lee, Wan-Ling, Pandita, Tej K., Bassing, Craig H., Sleckman, Barry P.
Publicado 2009

Evolution of antibody immunity following Omicron BA.1 breakthrough infection

por Kaku, Chengzi I., Starr, Tyler N., Zhou, Panpan, Dugan, Haley L., Khalifé, Paul, Song, Ge, Champney, Elizabeth R., Mielcarz, Daniel W., Geoghegan, James C., Burton, Dennis R., Andrabi, Raiees, Bloom, Jesse D., Walker, Laura M.
Publicado 2023

Evolution of antibody immunity following Omicron BA.1 breakthrough infection

por Kaku, Chengzi I., Starr, Tyler N., Zhou, Panpan, Dugan, Haley L., Khalifé, Paul, Song, Ge, Champney, Elizabeth R., Mielcarz, Daniel W., Geoghegan, James C., Burton, Dennis R., Raiees, Andrabi, Bloom, Jesse D., Walker, Laura M.
Publicado 2022

Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

por Chernyshev, Mark, Sakharkar, Mrunal, Connor, Ruth I., Dugan, Haley L., Sheward, Daniel J., Rappazzo, C. G., Stålmarck, Aron, Forsell, Mattias N. E., Wright, Peter F., Corcoran, Martin, Murrell, Ben, Walker, Laura M., Karlsson Hedestam, Gunilla B.
Publicado 2023

Prolonged evolution of the human B cell response to SARS-CoV-2 infection

por Sakharkar, Mrunal, Rappazzo, C. Garrett, Wieland-Alter, Wendy F., Hsieh, Ching-Lin, Wrapp, Daniel, Esterman, Emma S., Kaku, Chengzi I., Wec, Anna Z., Geoghegan, James C., McLellan, Jason S., Connor, Ruth I., Wright, Peter F., Walker, Laura M.
Publicado 2021

Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19

por Zumbrun, Elizabeth E., Kaku, Chengzi I., Dillinger, Lukas, Zak, Samantha E., Kuehne, Ana I., Bakken, Russel R., Koehler, Jeffrey W., Delp, Korey L., Stefan, Christopher P., Kumar, Raina, Kugelman, Jeffrey R., Moreau, Alicia M., Zeng, Xiankun, Dye, John M., Herbert, Andrew S., Narayan, Kristin, Walker, Laura M.
Publicado 2022