Screening approaches to generating STAT inhibitors: Allowing the hits to identify the targets

por Walker, Sarah R., Frank, David A.
Publicado 2012

Targeting BCL6 and STAT3 in triple negative breast cancer: the one-two punch?

por Walker, Sarah R., Frank, David A.
Publicado 2015

STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b

por Walker, Sarah R., Xiang, Michael, Frank, David A.
Publicado 2014

The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells()

por Egusquiaguirre, Susana P., Yeh, Jennifer E., Walker, Sarah R., Liu, Suhu, Frank, David A.
Publicado 2018

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K–AKT and JAK–STAT3 pathways

por Yuzugullu, Haluk, Von, Thanh, Thorpe, Lauren M, Walker, Sarah R, Roberts, Thomas M, Frank, David A, Zhao, Jean J
Publicado 2016

Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer

por Yeh, Jennifer E., Kreimer, Simion, Walker, Sarah R., Emori, Megan M., Krystal, Hannah, Richardson, Andrea, Ivanov, Alexander R., Frank, David A.
Publicado 2015

The transcriptional modulator BCL6 as a molecular target for breast cancer therapy

por Walker, Sarah R., Liu, Suhu, Xiang, Michael, Nicolais, Maria, Hatzi, Katerina, Giannopoulou, Eugenia, Elemento, Olivier, Cerchietti, Leandro, Melnick, Ari, Frank, David A.
Publicado 2014

Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-Palmitoylation

por Niu, Jixiao, Sun, Yang, Chen, Baoen, Zheng, Baohui, Jarugumilli, Gopala K., Walker, Sarah R., Hata, Aaron N., Mino-Kenudson, Mari, Frank, David A., Wu, Xu
Publicado 2019

CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3

por Egusquiaguirre, Susana P., Liu, Suhu, Tošić, Isidora, Jiang, Kevin, Walker, Sarah R., Nicolais, Maria, Saw, Tzuen Yih, Xiang, Michael, Bartel, Katarina, Nelson, Erik A., Frank, David A.
Publicado 2019

Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

por Chmielecki, Juliann, Crago, Aimee M., Rosenberg, Mara, O'Connor, Rachael, Walker, Sarah R., Ambrogio, Lauren, Auclair, Daniel, McKenna, Aaron, Heinrich, Michael C., Frank, David A., Meyerson, Matthew
Publicado 2013

Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts

por Chen, Chun-Hau, Bhasin, Swati, Khanna, Prateek, Joshi, Mukta, Joslin, Patrick MN., Saxena, Ruchi, Amin, Seema, Liu, Suhu, Sindhu, Shreya, Walker, Sarah R., Catalano, Paul, Frank, David A., Alper, Seth L., Bhasin, Manoj, Bhatt, Rupal S.
Publicado 2019

The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase

por Heppler, Lisa N., Attarha, Sanaz, Persaud, Rosanne, Brown, Jennifer I., Wang, Peng, Petrova, Boryana, Tošić, Isidora, Burton, Foster B., Flamand, Yael, Walker, Sarah R., Yeh, Jennifer E., Zubarev, Roman A., Gaetani, Massimiliano, Kanarek, Naama, Page, Brent D.G., Frank, David A.
Publicado 2021

Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM)

por Lapidot, Moshe, Case, Abigail E., Weisberg, Ellen L., Meng, Chengcheng, Walker, Sarah R., Garg, Swati, Ni, Wei, Podar, Klaus, Hung, Yin P., Carrasco, Ruben D., Knott, Aine, Gokhale, Prafulla C., Sharma, Sunil, Pozhitkov, Alex, Kulkarni, Prakash, Frank, David A., Salgia, Ravi, Griffin, James D., Saladi, Srinivas V., Bueno, Raphael, Sattler, Martin
Publicado 2021