Commentary: Age-related neurodegenerative disease research needs aging models

por Wallace, Lindsay M. K., Howlett, Susan E.
Publicado 2016

Cumulative health deficits, APOE genotype, and risk for later-life mild cognitive impairment and dementia

por Ward, David D, Wallace, Lindsay M K, Rockwood, Kenneth
Publicado 2021

Dose-dependent Toxicity of Humanized Renilla reniformis GFP (hrGFP) Limits Its Utility as a Reporter Gene in Mouse Muscle

por Wallace, Lindsay M, Moreo, Andrew, Clark, K Reed, Harper, Scott Q
Publicado 2013

THE ROLE OF FRAILTY IN DEMENTIA EXPRESSION: EVIDENCE FROM CLINICAL-PATHOLOGIC COHORT STUDIES

por Wallace, Lindsay M, Theou, Olga, Andrew, Melissa K, Bennett, David, Brayne, Carol, Rockwood, Kenneth
Publicado 2019

Frailty, lifestyle, genetics and dementia risk

por Ward, David D, Ranson, Janice M, Wallace, Lindsay M K, Llewellyn, David J, Rockwood, Kenneth
Publicado 2022

10‐year frailty trajectory is associated with Alzheimer’s dementia after considering neuropathological burden

por Wallace, Lindsay M. K., Theou, Olga, Godin, Judith, Ward, David D., Andrew, Melissa K., Bennett, David A., Rockwood, Kenneth
Publicado 2021

Accumulation of Non-Traditional Risk Factors for Coronary Heart Disease Is Associated with Incident Coronary Heart Disease Hospitalization and Death

por Wallace, Lindsay M. K., Theou, Olga, Kirkland, Susan A., Rockwood, Michael R. H., Davidson, Karina W., Shimbo, Daichi, Rockwood, Kenneth
Publicado 2014

Aberrant Splicing in Transgenes Containing Introns, Exons, and V5 Epitopes: Lessons from Developing an FSHD Mouse Model Expressing a D4Z4 Repeat with Flanking Genomic Sequences

por Ansseau, Eugénie, Domire, Jacqueline S., Wallace, Lindsay M., Eidahl, Jocelyn O., Guckes, Susan M., Giesige, Carlee R., Pyne, Nettie K., Belayew, Alexandra, Harper, Scott Q.
Publicado 2015

Predictors of transitions in frailty severity and mortality among people aging with HIV

por Brothers, Thomas D., Kirkland, Susan, Theou, Olga, Zona, Stefano, Malagoli, Andrea, Wallace, Lindsay M. K., Stentarelli, Chiara, Mussini, Cristina, Falutz, Julian, Guaraldi, Giovanni, Rockwood, Kenneth
Publicado 2017

Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4

por Eidahl, Jocelyn O., Giesige, Carlee R., Domire, Jacqueline S., Wallace, Lindsay M., Fowler, Allison M., Guckes, Susan M., Garwick-Coppens, Sara E., Labhart, Paul, Harper, Scott Q.
Publicado 2016

CCCDTD5: Reducing the risk of later‐life dementia. Evidence informing the Fifth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD‐5)

por Rockwood, Kenneth, Andrew, Melissa K., Aubertin‐Leheudre, Mylène, Belleville, Sylvie, Bherer, Louis, Bowles, Susan K., Kehler, D Scott, Lim, Andrew, Middleton, Laura, Phillips, Natalie, Wallace, Lindsay M.K.
Publicado 2020

RNAi-mediated Gene Silencing of Mutant Myotilin Improves Myopathy in LGMD1A Mice

por Liu, Jian, Wallace, Lindsay M, Garwick-Coppens, Sara E, Sloboda, Darcée D, Davis, Carol S, Hakim, Chady H, Hauser, Michael A, Brooks, Susan V, Mendell, Jerry R, Harper, Scott Q
Publicado 2014

Pre-clinical Safety and Off-Target Studies to Support Translation of AAV-Mediated RNAi Therapy for FSHD

por Wallace, Lindsay M., Saad, Nizar Y., Pyne, Nettie K., Fowler, Allison M., Eidahl, Jocelyn O., Domire, Jacqueline S., Griffin, Danielle A., Herman, Adam C., Sahenk, Zarife, Rodino-Klapac, Louise R., Harper, Scott Q.
Publicado 2017

A translatable RNAi-driven gene therapy silences PMP22/Pmp22 genes and improves neuropathy in CMT1A mice

por Stavrou, Marina, Kagiava, Alexia, Choudury, Sarah G., Jennings, Matthew J., Wallace, Lindsay M., Fowler, Allison M., Heslegrave, Amanda, Richter, Jan, Tryfonos, Christina, Christodoulou, Christina, Zetterberg, Henrik, Horvath, Rita, Harper, Scott Q., Kleopa, Kleopas A.
Publicado 2022

Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

por Lam, Phuong T., Padula, Stephanie L., Hoang, Thanh V., Poth, Justin E., Liu, Lin, Liang, Chun, LeFever, Adam S., Wallace, Lindsay M., Ashery-Padan, Ruth, Riggs, Penny K., Shields, Jordan E., Shaham, Ohad, Rowan, Sheldon, Brown, Nadean L., Glaser, Tom, Robinson, Michael L.
Publicado 2019

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Hughes, Brandon S., Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023