Cryptochromes Suppress HIF1α in Muscles

por Vaughan, Megan E., Wallace, Martina, Handzlik, Michal K., Chan, Alanna B., Metallo, Christian M., Lamia, Katja A.
Publicado 2020

Branched chain amino acid catabolism fuels adipocyte differentiation and lipogenesis

por Green, Courtney R., Wallace, Martina, Divakaruni, Ajit S., Phillips, Susan A., Murphy, Anne N., Ciaraldi, Theodore P., Metallo, Christian M.
Publicado 2015

Microbiota control of maternal behavior regulates early postnatal growth of offspring

por Lee, Yujung Michelle, Mu, Andre, Wallace, Martina, Gengatharan, Jivani M., Furst, Annalee J., Bode, Lars, Metallo, Christian M., Ayres, Janelle S.
Publicado 2021

Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism

por Tang, Yuefeng, Wallace, Martina, Sanchez-Gurmaches, Joan, Hsiao, Wen-Yu, Li, Huawei, Lee, Peter L., Vernia, Santiago, Metallo, Christian M., Guertin, David A.
Publicado 2016

The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis

por Acevedo, Aracely, Jones, Anthony E., Danna, Bezawit T., Turner, Rory, Montales, Katrina P., Benincá, Cristiane, Reue, Karen, Shirihai, Orian S., Stiles, Linsey, Wallace, Martina, Wang, Yibin, Bertholet, Ambre M., Divakaruni, Ajit S.
Publicado 2023

Serine restriction alters sphingolipid diversity to constrain tumor growth

por Muthusamy, Thangaselvam, Cordes, Thekla, Handzlik, Michal K., You, Le, Lim, Esther W., Gengatharan, Jivani, Pinto, Antonio F. M., Badur, Mehmet G., Kolar, Matthew J., Wallace, Martina, Saghatelian, Alan, Metallo, Christian M.
Publicado 2020

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

por Fernandez, Sully, Viola, John M., Torres, AnnMarie, Wallace, Martina, Trefely, Sophie, Zhao, Steven, Affronti, Hayley C., Gengatharan, Jivani M., Guertin, David A., Snyder, Nathaniel W., Metallo, Christian M., Wellen, Kathryn E.
Publicado 2019

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

por Divakaruni, Ajit S., Wallace, Martina, Buren, Caodu, Martyniuk, Kelly, Andreyev, Alexander Y., Li, Edward, Fields, Jerel A., Cordes, Thekla, Reynolds, Ian J., Bloodgood, Brenda L., Raymond, Lynn A., Metallo, Christian M., Murphy, Anne N.
Publicado 2017

Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function

por Wortham, Matthew, Benthuysen, Jacqueline R., Wallace, Martina, Savas, Jeffrey N., Mulas, Francesca, Divakaruni, Ajit S., Liu, Fenfen, Albert, Verena, Taylor, Brandon L., Sui, Yinghui, Saez, Enrique, Murphy, Anne N., Yates, John R., Metallo, Christian M., Sander, Maike
Publicado 2018

Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD

por Garcia, Daniel, Hellberg, Kristina, Chaix, Amandine, Wallace, Martina, Herzig, Sébastien, Badur, Mehmet G., Lin, Terry, Shokhirev, Maxim N., Pinto, Antonio F.M., Ross, Debbie S., Saghatelian, Alan, Panda, Satchidananda, Dow, Lukas E., Metallo, Christian M., Shaw, Reuben J.
Publicado 2019

Urinary Metabolomic Changes Accompanying Albuminuria Remission following Gastric Bypass Surgery for Type 2 Diabetic Kidney Disease

por Martin, William P., Malmodin, Daniel, Pedersen, Anders, Wallace, Martina, Fändriks, Lars, Aboud, Cristina M., Petry, Tarissa B. Zanata, Cunha da Silveira, Lívia P., da Costa Silva, Ana C. Calmon, Cohen, Ricardo V., le Roux, Carel W., Docherty, Neil G.
Publicado 2022

iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function

por Eade, Kevin T., Ansell, Brendan Robert E., Giles, Sarah, Fallon, Regis, Harkins-Perry, Sarah, Nagasaki, Takayuki, Tzaridis, Simone, Wallace, Martina, Mills, Elizabeth A., Farashi, Samaneh, Johnson, Alec, Sauer, Lydia, Hart, Barbara, Diaz-Rubio, M. Elena, Bahlo, Melanie, Metallo, Christian, Allikmets, Rando, Gantner, Marin L., Bernstein, Paul S., Friedlander, Martin
Publicado 2023

Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues

por Wallace, Martina, Green, Courtney R., Roberts, Lindsay S., Lee, Yujung Michelle, McCarville, Justin L., Sanchez-Gurmaches, Joan, Meurs, Noah, Gengatharan, Jivani M., Hover, Justin D., Phillips, Susan A., Ciaraldi, Theodore P., Guertin, David A., Cabrales, Pedro, Ayres, Janelle S., Nomura, Daniel K., Loomba, Rohit, Metallo, Christian M.
Publicado 2018

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small cell lung cancer in preclinical models

por Svensson, Robert U., Parker, Seth J., Eichner, Lillian J., Kolar, Matthew J., Wallace, Martina, Brun, Sonja N., Lombardo, Portia S., Van Nostrand, Jeanine L., Hutchins, Amanda, Vera, Lilliana, Gerken, Laurie, Greenwood, Jeremy, Bhat, Sathesh, Harriman, Geraldine, Westlin, William F., Harwood, H. James, Saghatelian, Alan, Kapeller, Rosana, Metallo, Christian M., Shaw, Reuben J.
Publicado 2016

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

por Wortham, Matthew, Liu, Fenfen, Harrington, Austin R., Fleischman, Johanna Y., Wallace, Martina, Mulas, Francesca, Mallick, Medhavi, Vinckier, Nicholas K., Cross, Benjamin R., Chiou, Joshua, Patel, Nisha A., Sui, Yinghui, McGrail, Carolyn, Jun, Yesl, Wang, Gaowei, Jhala, Ulupi S., Schüle, Roland, Shirihai, Orian S., Huising, Mark O., Gaulton, Kyle J., Metallo, Christian M., Sander, Maike
Publicado 2023

Insulin-regulated serine and lipid metabolism drive peripheral neuropathy

por Handzlik, Michal K., Gengatharan, Jivani M., Frizzi, Katie E., McGregor, Grace H., Martino, Cameron, Rahman, Gibraan, Gonzalez, Antonio, Moreno, Ana M., Green, Courtney R., Guernsey, Lucie S., Lin, Terry, Tseng, Patrick, Ideguchi, Yoichiro, Fallon, Regis J., Chaix, Amandine, Panda, Satchidananda, Mali, Prashant, Wallace, Martina, Knight, Rob, Gantner, Marin L., Calcutt, Nigel A., Metallo, Christian M.
Publicado 2023