Hypoxia and the regulation of myeloid cell metabolic imprinting: consequences for the inflammatory response

por Sadiku, Pranvera, Walmsley, Sarah R
Publicado 2019

Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function

por Walmsley, Sarah R, Chilvers, Edwin R, Whyte, Moira KB
Publicado 2009

The role of neutrophils in cancer

por Grecian, Robert, Whyte, Moira K B, Walmsley, Sarah R
Publicado 2018

HIF-mediated innate immune responses: cell signaling and therapeutic implications

por Harris, Alison J, Thompson, AA Roger, Whyte, Moira KB, Walmsley, Sarah R
Publicado 2014

Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models

por Elks, Philip M., Renshaw, Stephen A., Meijer, Annemarie H., Walmsley, Sarah R., van Eeden, Fredericus J.
Publicado 2015

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

por Elks, Philip M., Brizee, Sabrina, van der Vaart, Michiel, Walmsley, Sarah R., van Eeden, Fredericus J., Renshaw, Stephen A., Meijer, Annemarie H.
Publicado 2013

Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity

por Walmsley, Sarah R., Print, Cristin, Farahi, Neda, Peyssonnaux, Carole, Johnson, Randall S., Cramer, Thorsten, Sobolewski, Anastasia, Condliffe, Alison M., Cowburn, Andrew S., Johnson, Nicola, Chilvers, Edwin R.
Publicado 2005

Neutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle

por Willson, Joseph A., Arienti, Simone, Sadiku, Pranvera, Reyes, Leila, Coelho, Patricia, Morrison, Tyler, Rinaldi, Giulia, Dockrell, David H., Whyte, Moira K. B., Walmsley, Sarah R.
Publicado 2022

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

por Dickinson, Rebecca S., Murphy, Fiona, Doherty, Catherine, Williams, Sam, Mirchandani, Ananda, Willson, Joseph, Scotti, John S., Preston, Gail, Schofield, Christopher J., Whyte, Moira K.B., Walmsley, Sarah R.
Publicado 2017

Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival

por Juss, Jatinder K., Hayhoe, Richard P., Owen, Charles E., Bruce, Ian, Walmsley, Sarah R., Cowburn, Andrew S., Kulkarni, Suhasini, Boyle, Keith B., Stephens, Len, Hawkins, Phillip T., Chilvers, Edwin R., Condliffe, Alison M.
Publicado 2012

A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

por Marriott, Helen M, Daigneault, Marc, Thompson, Alfred A R, Walmsley, Sarah R, Gill, Sharonjit K, Witcher, Derrick R, Wroblewski, Victor J, Hellewell, Paul G, Whyte, Moira K B, Dockrell, David H
Publicado 2012

Hypoxia Modulates Platelet Purinergic Signalling Pathways

por Paterson, Gordon G., Young, Jason M., Willson, Joseph A., Graham, Christopher J., Dru, Rebecca C., Lee, Eleanor W., Torpey, Greig S., Walmsley, Sarah R., Chan, Melissa V., Warner, Timothy D., Baillie, John Kenneth, Thompson, Alfred Arthur Roger
Publicado 2020

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

por McGrath, Emmet E, Lawrie, Allan, Marriott, Helen M, Mercer, Paul, Cross, Simon S, Arnold, Nadine, Singleton, Vanessa, Thompson, Alfred A R, Walmsley, Sarah R, Renshaw, Stephen A, Sabroe, Ian, Chambers, Rachel C, Dockrell, David H, Whyte, Moira K B
Publicado 2012

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

por Harris, Alison J., Mirchandani, Ananda S., Lynch, Ruairi W., Murphy, Fiona, Delaney, Liam, Small, Donna, Coelho, Patricia, Watts, Emily R., Sadiku, Pranvera, Griffith, David, Dickinson, Rebecca S., Clark, Eilidh, Willson, Joseph A., Morrison, Tyler, Mazzone, Massimilliano, Carmeliet, Peter, Ghesquiere, Bart, O’Kane, Cecilia, McAuley, Danny, Jenkins, Steve J., Whyte, Moira K. B., Walmsley, Sarah R.
Publicado 2019

The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair( # )

por McCowan, Jack, Fercoq, Frédéric, Kirkwood, Phoebe M., T’Jonck, Wouter, Hegarty, Lizi M., Mawer, Connar M., Cunningham, Richard, Mirchandani, Ananda S., Hoy, Anna, Humphries, Duncan C., Jones, Gareth-Rhys, Hansen, Carsten G., Hirani, Nik, Jenkins, Stephen J., Henri, Sandrine, Malissen, Bernard, Walmsley, Sarah R., Dockrell, David H., Saunders, Philippa T. K., Carlin, Leo M., Bain, Calum C.
Publicado 2021

Semaphorin 3F signaling actively retains neutrophils at sites of inflammation

por Plant, Tracie, Eamsamarng, Suttida, Sanchez-Garcia, Manuel A., Reyes, Leila, Renshaw, Stephen A., Coelho, Patricia, Mirchandani, Ananda S., Morgan, Jessie-May, Ellett, Felix E., Morrison, Tyler, Humphries, Duncan, Watts, Emily R., Murphy, Fiona, Raffo-Iraolagoitia, Ximena L., Zhang, Ailiang, Cash, Jenna L., Loynes, Catherine, Elks, Philip M., Van Eeden, Freek, Carlin, Leo M., Furley, Andrew J.W., Whyte, Moira K.B., Walmsley, Sarah R.
Publicado 2020

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

por Sadiku, Pranvera, Willson, Joseph A., Dickinson, Rebecca S., Murphy, Fiona, Harris, Alison J., Lewis, Amy, Sammut, David, Mirchandani, Ananda S., Ryan, Eilise, Watts, Emily R., Thompson, A.A. Roger, Marriott, Helen M., Dockrell, David H., Taylor, Cormac T., Schneider, Martin, Maxwell, Patrick H., Chilvers, Edwin R., Mazzone, Massimilliano, Moral, Veronica, Pugh, Chris W., Ratcliffe, Peter J., Schofield, Christopher J., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Publicado 2017

NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease

por Ryan, Eilise M., Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R., Zhang, Ailiang, Howden, Andrew J. M., Sanchez-Garcia, Manuel A., Bewley, Martin, Cole, Joby, McHugh, Brian J., Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F., Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A., McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H., Whyte, Moira K. B., Walmsley, Sarah R.
Publicado 2023

­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­

por Reyes, Leila, A. Sanchez-Garcia, Manuel, Morrison, Tyler, Howden, Andy J. M., Watts, Emily R., Arienti, Simone, Sadiku, Pranvera, Coelho, Patricia, Mirchandani, Ananda S., Zhang, Ailiang, Hope, David, Clark, Sarah K., Singleton, Jo, Johnston, Shonna, Grecian, Robert, Poon, Azin, McNamara, Sarah, Harper, Isla, Fourman, Max Head, Brenes, Alejandro J., Pathak, Shalini, Lloyd, Amy, Blanco, Giovanny Rodriguez, von Kriegsheim, Alex, Ghesquiere, Bart, Vermaelen, Wesley, Cologna, Camila T., Dhaliwal, Kevin, Hirani, Nik, Dockrell, David H., Whyte, Moira K. B., Griffith, David, Cantrell, Doreen A., Walmsley, Sarah R.
Publicado 2021

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

por Sadiku, Pranvera, Willson, Joseph A., Ryan, Eilise M., Sammut, David, Coelho, Patricia, Watts, Emily R., Grecian, Robert, Young, Jason M., Bewley, Martin, Arienti, Simone, Mirchandani, Ananda S., Sanchez Garcia, Manuel A., Morrison, Tyler, Zhang, Ailing, Reyes, Leila, Griessler, Tobias, Jheeta, Privjyot, Paterson, Gordon G., Graham, Christopher J., Thomson, John P., Baillie, Kenneth, Thompson, A.A. Roger, Morgan, Jessie-May, Acosta-Sanchez, Abel, Dardé, Veronica M., Duran, Jordi, Guinovart, Joan J., Rodriguez-Blanco, Gio, Von Kriegsheim, Alex, Meehan, Richard R., Mazzone, Massimiliano, Dockrell, David H., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Publicado 2021