The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells

por Walsby, Elisabeth, Pearce, Lawrence, Burnett, Alan K., Fegan, Chris, Pepper, Chris
Publicado 2012

Phosphoramidates of 2′-β-d-arabinouridine (AraU) as phosphate prodrugs; design, synthesis, in vitro activity and metabolism

por Mehellou, Youcef, Valente, Rocco, Mottram, Huw, Walsby, Elisabeth, Mills, Kenneth I., Balzarini, Jan, McGuigan, Christopher
Publicado 2010

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine

por Walsby, Elisabeth, Pratt, Guy, Shao, Hao, Abbas, Abdullah Y., Fischer, Peter M., Bradshaw, Tracey D., Brennan, Paul, Fegan, Chris, Wang, Shudong, Pepper, Chris
Publicado 2013

Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit nuclear factor-κB activity and synergize with bortezomib and ibrutinib in hematologic cancers

por Lewis, Thomas, Corcoran, David B., Thurston, David E., Giles, Peter J., Ashelford, Kevin, Walsby, Elisabeth J., Fegan, Christopher D., Pepper, Andrea G. S., Rahman, Khondaker Miraz, Pepper, Chris
Publicado 2020

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

por Lam, Frankie, Abbas, Abdullahi Y., Shao, Hao, Teo, Theodosia, Adams, Julian, Li, Peng, Bradshaw, Tracey D., Fischer, Peter M., Walsby, Elisabeth, Pepper, Chris, Chen, Yi, Ding, Jian, Wang, Shudong
Publicado 2014