A Sequential Vesicle Pool Model with a Single Release Sensor and a Ca(2+)-Dependent Priming Catalyst Effectively Explains Ca(2+)-Dependent Properties of Neurosecretion

por Walter, Alexander M., Pinheiro, Paulo S., Verhage, Matthijs, Sørensen, Jakob B.
Publicado 2013

Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis

por Walter, Alexander M., Wiederhold, Katrin, Bruns, Dieter, Fasshauer, Dirk, Sørensen, Jakob B.
Publicado 2010

Allosteric stabilization of calcium and phosphoinositide dual binding engages several synaptotagmins in fast exocytosis

por Kobbersmed, Janus RL, Berns, Manon MM, Ditlevsen, Susanne, Sørensen, Jakob B, Walter, Alexander M
Publicado 2022

Spontaneous neurotransmission at evocable synapses predicts their responsiveness to action potentials

por Grasskamp, Andreas T., Jusyte, Meida, McCarthy, Anthony W., Götz, Torsten W. B., Ditlevsen, Susanne, Walter, Alexander M.
Publicado 2023

Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca(2+) channel distances

por Kobbersmed, Janus RL, Grasskamp, Andreas T, Jusyte, Meida, Böhme, Mathias A, Ditlevsen, Susanne, Sørensen, Jakob Balslev, Walter, Alexander M
Publicado 2020

Homeostatic scaling of active zone scaffolds maintains global synaptic strength

por Goel, Pragya, Dufour Bergeron, Dominique, Böhme, Mathias A., Nunnelly, Luke, Lehmann, Martin, Buser, Christopher, Walter, Alexander M., Sigrist, Stephan J., Dickman, Dion
Publicado 2019

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

por Man, Kwun Nok M, Imig, Cordelia, Walter, Alexander M, Pinheiro, Paulo S, Stevens, David R, Rettig, Jens, Sørensen, Jakob B, Cooper, Benjamin H, Brose, Nils, Wojcik, Sonja M
Publicado 2015

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

por Schuhmacher, Milena, Grasskamp, Andreas T., Barahtjan, Pavel, Wagner, Nicolai, Lombardot, Benoit, Schuhmacher, Jan S., Sala, Pia, Lohmann, Annett, Henry, Ian, Shevchenko, Andrej, Coskun, Ünal, Walter, Alexander M., Nadler, André
Publicado 2020

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

por Walter, Alexander M, Müller, Rainer, Tawfik, Bassam, Wierda, Keimpe DB, Pinheiro, Paulo S, Nadler, André, McCarthy, Anthony W, Ziomkiewicz, Iwona, Kruse, Martin, Reither, Gregor, Rettig, Jens, Lehmann, Martin, Haucke, Volker, Hille, Bertil, Schultz, Carsten, Sørensen, Jakob Balslev
Publicado 2017

Interactive nanocluster compaction of the ELKS scaffold and Cacophony Ca(2+) channels drives sustained active zone potentiation

por Ghelani, Tina, Escher, Marc, Thomas, Ulrich, Esch, Klara, Lützkendorf, Janine, Depner, Harald, Maglione, Marta, Parutto, Pierre, Gratz, Scott, Matkovic-Rachid, Tanja, Ryglewski, Stefanie, Walter, Alexander M., Holcman, David, O‘Connor Giles, Kate, Heine, Martin, Sigrist, Stephan J.
Publicado 2023

Rapid active zone remodeling consolidates presynaptic potentiation

por Böhme, Mathias A., McCarthy, Anthony W., Grasskamp, Andreas T., Beuschel, Christine B., Goel, Pragya, Jusyte, Meida, Laber, Desiree, Huang, Sheng, Rey, Ulises, Petzoldt, Astrid G., Lehmann, Martin, Göttfert, Fabian, Haghighi, Pejmun, Hell, Stefan W., Owald, David, Dickman, Dion, Sigrist, Stephan J., Walter, Alexander M.
Publicado 2019

Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

por Muhammad, Karzan, Reddy-Alla, Suneel, Driller, Jan H, Schreiner, Dietmar, Rey, Ulises, Böhme, Mathias A., Hollmann, Christina, Ramesh, Niraja, Depner, Harald, Lützkendorf, Janine, Matkovic, Tanja, Götz, Torsten, Bergeron, Dominique D., Schmoranzer, Jan, Goettfert, Fabian, Holt, Mathew, Wahl, Markus C., Hell, Stefan W., Scheiffele, Peter, Walter, Alexander M., Loll, Bernhard, Sigrist, Stephan J.
Publicado 2015