CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity

por Walton, Josephine B., Farquharson, Malcolm, Mason, Susan, Port, Jennifer, Kruspig, Bjorn, Dowson, Suzanne, Stevenson, David, Murphy, Daniel, Matzuk, Martin, Kim, Jaeyeon, Coffelt, Seth, Blyth, Karen, McNeish, Iain A.
Publicado 2017

Author Correction: CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity

por Walton, Josephine B., Farquharson, Malcolm, Mason, Susan, Port, Jennifer, Kruspig, Bjorn, Dowson, Suzanne, Stevenson, David, Murphy, Daniel, Matzuk, Martin, Kim, Jaeyeon, Coffelt, Seth, Blyth, Karen, McNeish, Iain A.
Publicado 2018

RIPK3 promotes adenovirus type 5 activity

por Weigert, Melanie, Binks, Alex, Dowson, Suzanne, Leung, Elaine Y. L., Athineos, Dimitris, Yu, Xinzi, Mullin, Margaret, Walton, Josephine B., Orange, Clare, Ennis, Darren, Blyth, Karen, Tait, Stephen W. G., McNeish, Iain A.
Publicado 2017

Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery

por Taylor, Molly A., Hughes, Adina M., Walton, Josephine, Coenen-Stass, Anna M. L., Magiera, Lukasz, Mooney, Lorraine, Bell, Sigourney, Staniszewska, Anna D., Sandin, Linda C., Barry, Simon T., Watkins, Amanda, Carnevalli, Larissa S., Hardaker, Elizabeth L.
Publicado 2019

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

por Blagih, Julianna, Zani, Fabio, Chakravarty, Probir, Hennequart, Marc, Pilley, Steven, Hobor, Sebastijan, Hock, Andreas K., Walton, Josephine B., Morton, Jennifer P., Gronroos, Eva, Mason, Susan, Yang, Ming, McNeish, Iain, Swanton, Charles, Blyth, Karen, Vousden, Karen H.
Publicado 2020

Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer

por Revenko, Alexey, Carnevalli, Larissa S, Sinclair, Charles, Johnson, Ben, Peter, Alison, Taylor, Molly, Hettrick, Lisa, Chapman, Melissa, Klein, Stephanie, Solanki, Anisha, Gattis, Danielle, Watt, Andrew, Hughes, Adina M, Magiera, Lukasz, Kar, Gozde, Ireland, Lucy, Mele, Deanna A, Sah, Vasu, Singh, Maneesh, Walton, Josephine, Mairesse, Maelle, King, Matthew, Edbrooke, Mark, Lyne, Paul, Barry, Simon T, Fawell, Stephen, Goldberg, Frederick W, MacLeod, A Robert
Publicado 2022

Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

por Bruand, Marine, Barras, David, Mina, Marco, Ghisoni, Eleonora, Morotti, Matteo, Lanitis, Evripidis, Fahr, Noémie, Desbuisson, Mathieu, Grimm, Alizée, Zhang, Hualing, Chong, Chloe, Dagher, Julien, Chee, Sora, Tsianou, Theodora, Dorier, Julien, Stevenson, Brian J., Iseli, Christian, Ronet, Catherine, Bobisse, Sara, Genolet, Raphael, Walton, Josephine, Bassani-Sternberg, Michal, Kandalaft, Lana E., Ren, Bing, McNeish, Iain, Swisher, Elizabeth, Harari, Alexandre, Delorenzi, Mauro, Ciriello, Giovanni, Irving, Melita, Rusakiewicz, Sylvie, Foukas, Periklis G., Martinon, Fabio, Dangaj Laniti, Denarda, Coukos, George
Publicado 2021