PKPD modeling of acquired resistance to anti-cancer drug treatment

por Eigenmann, Miro J., Frances, Nicolas, Lavé, Thierry, Walz, Antje-Christine
Publicado 2017

Filter inference: A scalable nonlinear mixed effects inference approach for snapshot time series data

por Augustin, David, Lambert, Ben, Wang, Ken, Walz, Antje-Christine, Robinson, Martin, Gavaghan, David
Publicado 2023

Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer

por Bouhaddou, Mehdi, Yu, Li J., Lunardi, Serena, Stamatelos, Spyros K., Mack, Fiona, Gallo, James M., Birtwistle, Marc R., Walz, Antje‐Christine
Publicado 2020

Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration

por Van De Vyver, Arthur J., Walz, Antje-Christine, Heins, Mariette S., Abdolzade-Bavil, Afsaneh, Kraft, Thomas E., Waldhauer, Inja, Otteneder, Michael B.
Publicado 2022

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

por Davies, Mark R., Wang, Ken, Mirams, Gary R., Caruso, Antonello, Noble, Denis, Walz, Antje, Lavé, Thierry, Schuler, Franz, Singer, Thomas, Polonchuk, Liudmila
Publicado 2016

PK/PD Mediated Dose Optimization of Emactuzumab, a CSF1R Inhibitor, in Patients With Advanced Solid Tumors and Diffuse‐Type Tenosynovial Giant Cell Tumor

por Smart, Kevin, Bröske, Ann‐Marie, Rüttinger, Dominik, Mueller, Claudia, Phipps, Alex, Walz, Antje‐Christine, Ries, Carola, Baehner, Monika, Cannarile, Michael, Meneses‐Lorente, Georgina
Publicado 2020

A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis

por Van De Vyver, Arthur, Eigenmann, Miro, Ovacik, Meric, Pohl, Christian, Herter, Sylvia, Weinzierl, Tina, Fauti, Tanja, Klein, Christian, Lehr, Thorsten, Bacac, Marina, Walz, Antje-Christine
Publicado 2021

Passive immunization against COVID-19 by anti-SARS-CoV-2 spike IgG in commercially available immunoglobulin preparations in severe antibody deficiency

por Hirsiger, Julia R., Weigang, Sebastian, Walz, Antje-Christine, Fuchs, Jonas, Daly, Mary-Louise, Eggimann, Stefan, Hausmann, Oliver, Schwemmle, Martin, Kochs, Georg, Panning, Marcus, Warnatz, Klaus, Recher, Mike, Berger, Christoph T.
Publicado 2022

Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid

por Eigenmann, Miro Julian, Karlsen, Tine Veronica, Wagner, Marek, Tenstad, Olav, Weinzierl, Tina, Fauti, Tanja, Grimm, Hans Peter, Skogstrand, Trude, Klein, Christian, Sam, Johannes, Umana, Pablo, Bacac, Marina, Wiig, Helge, Walz, Antje-Christine
Publicado 2021

Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodies

por Leclercq, Gabrielle, Haegel, Hélène, Schneider, Anneliese, Giusti, Anna Maria, Marrer-Berger, Estelle, Boetsch, Christophe, Walz, Antje-Christine, Pulko, Vesna, Sam, Johannes, Challier, John, Ferlini, Cristiano, Odermatt, Alex, Umaña, Pablo, Bacac, Marina, Klein, Christian
Publicado 2021

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

por Vey, Norbert, Delaunay, Jacques, Martinelli, Giovanni, Fiedler, Walter, Raffoux, Emmanuel, Prebet, Thomas, Gomez-Roca, Carlos, Papayannidis, Cristina, Kebenko, Maxim, Paschka, Peter, Christen, Randolph, Guarin, Ernesto, Bröske, Ann-Marie, Baehner, Monika, Brewster, Michael, Walz, Antje-Christine, Michielin, Francesca, Runza, Valeria, Meresse, Valerie, Recher, Christian
Publicado 2016

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

por Menke-van der Houven van Oordt, C. Willemien, Gomez-Roca, Carlos, van Herpen, Carla, Coveler, Andrew L., Mahalingam, Devalingam, Verheul, Henk M. W., van der Graaf, Winette T. A., Christen, Randolph, Rüttinger, Dominik, Weigand, Stefan, Cannarile, Michael A., Heil, Florian, Brewster, Michael, Walz, Antje-Christine, Nayak, Tapan K., Guarin, Ernesto, Meresse, Valerie, Le Tourneau, Christophe
Publicado 2016