Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia

por Kerstjens, Mark, Garrido Castro, Patricia, Pinhanços, Sandra S., Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.
Publicado 2021

CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia

por Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S., Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W.
Publicado 2023

FLT3(N676K) drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

por Hyrenius-Wittsten, Axel, Pilheden, Mattias, Falqués-Costa, Antoni, Eriksson, Mia, Sturesson, Helena, Schneider, Pauline, Wander, Priscilla, Garcia-Ruiz, Cristian, Liu, Jian, Ågerstam, Helena, Hultquist, Anne, Lilljebjörn, Henrik, Stam, Ronald W., Järås, Marcus, Hagström-Andersson, Anna K.
Publicado 2019

High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling

por Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Pinhanҫos, Sandra Mimoso, Koopmans, Bianca, Dolman, M. Emmy M., Jones, Luke, Garrido Castro, Patricia, Schneider, Pauline, Kerstjens, Mark, Molenaar, Jan J., Pieters, Rob, Zwaan, Christian Michel, Stam, Ronald W.
Publicado 2022

The clinical and biological characteristics of NUP98-KDM5A pediatric acute myeloid leukemia

por Noort, Sanne, Wander, Priscilla, Alonzo, Todd A., Smith, Jenny, Ries, Rhonda E., Gerbing, Robert B., Dolman, M. Emmy M., Locatelli, Franco, Reinhardt, Dirk, Baruchel, Andre, Stary, Jan, Molenaar, Jan J., Stam, Ronald W., van den Heuvel-Eibrink, Marry M., Zwaan, C. Michel, Meshinchi, Soheil
Publicado 2020

High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia

por Wander, Priscilla, Arentsen-Peters, Susan T.C.J.M., Pinhanҫos, Sandra S., Koopmans, Bianca, Dolman, M.Emmy M., Ariese, Rijndert, Bos, Frank L., Castro, Patricia Garrido, Jones, Luke, Schneider, Pauline, Navarro, Miriam Guillen, Molenaar, Jan J., Rios, Anne C., Zwaan, C. Michel, Stam, Ronald W.
Publicado 2021