Coadministration of bedaquiline and pyrifazimine reduce exposure to toxic metabolite N-desmethyl bedaquiline

por Ding, Yangming, Liu, Haiting, Wang, Furun, Fu, Lei, Zhu, Hui, Fu, Shuang, Wang, Ning, Zhuang, Xiaomei, Lu, Yu
Publicado 2023

A PBPK Model of Ternary Cyclodextrin Complex of ST-246 Was Built to Achieve a Reasonable IV Infusion Regimen for the Treatment of Human Severe Smallpox

por Zhang, Zhiwei, Fu, Shuang, Wang, Furun, Yang, Chunmiao, Wang, Lingchao, Yang, Meiyan, Zhang, Wenpeng, Zhong, Wu, Zhuang, Xiaomei
Publicado 2022

Alternation of Organ-Specific Exposure in LPS-Induced Pneumonia Mice after the Inhalation of Tetrandrine Is Governed by Metabolizing Enzyme Suppression and Lysosomal Trapping

por Wang, Furun, Jiang, Xue, Yang, Zengxu, Fu, Shuang, Yao, Shi, Wang, Lingchao, Lv, Yue, Zhang, Wenpeng, Ding, Rigao, Zhuang, Xiaomei
Publicado 2022

Antiviral effects and tissue exposure of tetrandrine against SARS‐CoV‐2 infection and COVID‐19

por Liu, Jia, Wang, Furun, Wang, Xi, Fan, Shiyong, Li, Yufeng, Xu, Mingyue, Hu, Hengrui, Liu, Ke, Zheng, Bohong, Wang, Lingchao, Zhang, Huanyu, Li, Jiang, Li, Wei, Zhang, Wenpeng, Hu, Zhihong, Cao, Ruiyuan, Zhuang, Xiaomei, Wang, Manli, Zhong, Wu
Publicado 2023