Fulvestrant as a reference antiestrogen and estrogen receptor (ER) degrader in preclinical studies: treatment dosage, efficacy, and implications on development of new ER-targeting...

por Wang, Guangdi
Publicado 2020

Advances in the proteomic discovery of novel therapeutic targets in cancer

por Guo, Shanchun, Zou, Jin, Wang, Guangdi
Publicado 2013

Glutathione peroxidases as oncotargets

por Jiao, Yang, Wang, Yirong, Guo, Shanchun, Wang, Guangdi
Publicado 2017

From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target

por Mottamal, Madhusoodanan, Kang, Borui, Peng, Xianyou, Wang, Guangdi
Publicado 2021

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

por Mottamal, Madhusoodanan, Zheng, Shilong, Huang, Tien L., Wang, Guangdi
Publicado 2015

GREB1 Functions as a Growth Promoter and Is Modulated by IL6/STAT3 in Breast Cancer

por Liu, Mingli, Wang, Guangdi, Gomez-Fernandez, Carmen R., Guo, Shanchun
Publicado 2012

Synergistic effects of combined treatment with histone deacetylase inhibitor suberoylanilide hydroxamic acid and TRAIL on human breast cancer cells

por Zhou, Weiqiang, Feng, Xiuyan, Han Han, Guo, Shanchun, Wang, Guangdi
Publicado 2016

Synthesis and Antitumor Activity of a Series of Novel 1-Oxa-4-azaspiro[4,5]deca-6,9-diene-3,8-dione Derivatives

por Yang, Ze, Zhong, Qiu, Zheng, Shilong, Wang, Guangdi, He, Ling
Publicado 2019

New Zampanolide Mimics: Design, Synthesis, and Antiproliferative Evaluation

por Chen, Guanglin, Jiang, Ziran, Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong
Publicado 2020

3-O-Carbamoyl-5,7,20-O-trimethylsilybins: Synthesis and Preliminary Antiproliferative Evaluation

por Wu, Sitong, Chen, Guanglin, Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong
Publicado 2021

Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

por Zhong, Qiu, Zhang, Changde, Zhang, Qiang, Miele, Lucio, Zheng, Shilong, Wang, Guangdi
Publicado 2015

Design, Synthesis, and Antitumor Activity of a Series of Novel 4-(Aromatic Sulfonyl)-1-oxa-4-azaspiro[4.5]deca-6,9-dien-8-ones

por Xing, Naiguo, Chen, Chen, Zhong, Qiu, Zheng, Shilong, Wang, Guangdi, He, Ling
Publicado 2020

Ligands of Therapeutic Utility for the Liver X Receptors

por Komati, Rajesh, Spadoni, Dominick, Zheng, Shilong, Sridhar, Jayalakshmi, Riley, Kevin E., Wang, Guangdi
Publicado 2017

Efficient Dual-Site Carbon Monoxide Electro-Catalysts via Interfacial Nano-Engineering

por Liu, Zhen, Huang, Zhongyuan, Cheng, Feifei, Guo, Zhanhu, Wang, Guangdi, Chen, Xu, Wang, Zhe
Publicado 2016

Design and Synthesis of N(1),N(5)-bis[4-(5-Alkyl-1,2,4-oxadiazol-3-yl)phenyl]glutaramides as Potential Antifungal Prodrugs

por Kode, Nageswara Rao, Vanden Eynde, Jean J., Mayence, Annie, Wang, Guangdi, Huang, Tien L.
Publicado 2013

SAT-341 Pharmacology and Metabolism of GLL398 an Oral Selective Estrogen Receptor Degrader for Endocrine Therapy of Breast Cancer

por Guo, Shanchun, Hossain, Ahamed, Zhang, Changde, Mottamal, Madhu, Liu, Jiawang, Wiese, Thomas, Wang, Guangdi
Publicado 2019

Metabolism and Pharmacokinetic Study of the Boron-Containing Prodrug of Belinostat (ZL277), a Pan HDAC Inhibitor with Enhanced Bioavailability

por Zhang, Changde, Guo, Shanchun, Zhong, Qiu, Zhang, Qiang, Hossain, Ahamed, Zheng, Shilong, Wang, Guangdi
Publicado 2019

TRPM7 Induces Mechanistic Target of Rap1b Through the Downregulation of miR-28-5p in Glioma Proliferation and Invasion

por Wan, Jingwei, Guo, Alyssa Aihui, Chowdhury, Indrajit, Guo, Shanchun, Hibbert, Jacqueline, Wang, Guangdi, Liu, Mingli
Publicado 2019

Core Structure–Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models

por Wu, Sitong, Chen, Guanglin, Chen, Eva Y., Farshidpour, Leyla S., Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong
Publicado 2023

Discovery of Novel Pentacyclic Triterpene Acid Amide Derivatives as Excellent Antimicrobial Agents Dependent on Generation of Reactive Oxygen Species

por Yang, Yihong, Chen, Kunlun, Wang, Guangdi, Liu, Hongwu, Shao, Lihui, Zhou, Xiang, Liu, Liwei, Yang, Song
Publicado 2023