Learning the solution operator of parametric partial differential equations with physics-informed DeepONets

por Wang, Sifan, Wang, Hanwen, Perdikaris, Paris
Publicado 2021

Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition

por Wang, Hanwen, Arulraj, Theinmozhi, Kimko, Holly, Popel, Aleksander S.
Publicado 2023

Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition

por Wang, Hanwen, Arulraj, Theinmozhi, Kimko, Holly, Popel, Aleksander S.
Publicado 2023

Comprehensive analysis identifies IFI16 as a novel signature associated with overall survival and immune infiltration of skin cutaneous melanoma

por Wang, Hanwen, Xie, Xiaoxia, Zhu, Junyou, Qi, Shaohai, Xie, Julin
Publicado 2021

Intracranial electrophysiological recordings on a swine model of mesial temporal lobe epilepsy

por Zhu, Fengjun, Wang, Hanwen, Li, Lin, Bragin, Anatol, Cao, Dezhi, Cheng, Yuan
Publicado 2023

High-Temperature Pyrolysis of N-Tetracosane Based on ReaxFF Molecular Dynamics Simulation

por Yu, Xiaowen, Zhang, Chunhua, Wang, Hanwen, Li, Yangyang, Kang, Yujia, Yang, Ke
Publicado 2023

Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer

por Wang, Hanwen, Ma, Huilin, Sové, Richard J, Emens, Leisha A, Popel, Aleksander S
Publicado 2021

Systems biology of angiogenesis signaling: Computational models and omics

por Zhang, Yu, Wang, Hanwen, Oliveira, Rebeca Hannah M., Zhao, Chen, Popel, Aleksander S.
Publicado 2021

A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition

por Arulraj, Theinmozhi, Wang, Hanwen, Emens, Leisha A., Santa-Maria, Cesar A., Popel, Aleksander S.
Publicado 2023

Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model

por Ma, Huilin, Wang, Hanwen, Sové, Richard J, Wang, Jun, Giragossian, Craig, Popel, Aleksander S
Publicado 2020

QSP‐IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno‐Oncology Applications

por Sové, Richard J., Jafarnejad, Mohammad, Zhao, Chen, Wang, Hanwen, Ma, Huilin, Popel, Aleksander S.
Publicado 2020

Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of immunotherapy in triple-negative breast cancer

por Wang, Hanwen, Zhao, Chen, Santa-Maria, Cesar A., Emens, Leisha A., Popel, Aleksander S.
Publicado 2022

Correlation between the Molecular Structure and Viscosity Index of CTL Base Oils Based on Ridge Regression

por Zhang, Chunhua, Wang, Hanwen, Yu, Xiaowen, Peng, Chaolin, Zhang, Angui, Liang, Xuemei, Yan, Yinan
Publicado 2022

In-plane anisotropic electronics based on low-symmetry 2D materials: progress and prospects

por Zhao, Siwen, Dong, Baojuan, Wang, Huide, Wang, Hanwen, Zhang, Yupeng, Han, Zheng Vitto, Zhang, Han
Publicado 2019

Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model

por Sové, Richard J, Verma, Babita K, Wang, Hanwen, Ho, Won Jin, Yarchoan, Mark, Popel, Aleksander S
Publicado 2022

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

por Anbari, Samira, Wang, Hanwen, Zhang, Yu, Wang, Jun, Pilvankar, Minu, Nickaeen, Masoud, Hansel, Steven, Popel, Aleksander S.
Publicado 2023

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

por Ruiz-Martinez, Alvaro, Gong, Chang, Wang, Hanwen, Sové, Richard J., Mi, Haoyang, Kimko, Holly, Popel, Aleksander S.
Publicado 2022

A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor

por Ma, Huilin, Wang, Hanwen, Sove, Richard J., Jafarnejad, Mohammad, Tsai, Chia-Hung, Wang, Jun, Giragossian, Craig, Popel, Aleksander S.
Publicado 2020

Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response

por Zhang, Shuming, Gong, Chang, Ruiz-Martinez, Alvaro, Wang, Hanwen, Davis-Marcisak, Emily, Deshpande, Atul, Popel, Aleksander S., Fertig, Elana J.
Publicado 2021

Identification of molecular subgroups and establishment of risk model based on the response to oxidative stress to predict overall survival of patients with lung adenocarcinoma

por Liu, Linzhuang, Hou, Qinghua, Chen, Baorong, Lai, Xiyi, Wang, Hanwen, Liu, Haozhen, Wu, Liusheng, Liu, Sheng, Luo, Kelin, Liu, Jixian
Publicado 2023