Potential drug-drug interaction of olverembatinib (HQP1351) using physiologically based pharmacokinetic models

por Yu, Zhiheng, Lei, Zihan, Yao, Xueting, Wang, Hengbang, Zhang, Miao, Hou, Zhe, Li, Yafen, Zhao, Yangyu, Li, Haiyan, Liu, Dongyang, Zhai, Yifan
Publicado 2022

Discovery of 4-((3′R,4′S,5′R)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carbo...

por Aguilar, Angelo, Lu, Jianfeng, Liu, Liu, Du, Ding, Bernard, Denzil, McEachern, Donna, Przybranowski, Sally, Li, Xiaoqin, Luo, Ruijuan, Wen, Bo, Sun, Duxin, Wang, Hengbang, Wen, Jianfeng, Wang, Guangfeng, Zhai, Yifan, Guo, Ming, Yang, Dajun, Wang, Shaomeng
Publicado 2017

Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter p...

por Jiang, Qian, Li, Zongru, Qin, Yazhen, Li, Weiming, Xu, Na, Liu, Bingcheng, Zhang, Yanli, Meng, Li, Zhu, Huanling, Du, Xin, Chen, Suning, Liang, Yang, Hu, Yu, Liu, Xiaoli, Song, Yongping, Men, Lichuang, Chen, Zi, Niu, Qian, Wang, Hengbang, Lu, Ming, Yang, Dajun, Zhai, Yifan, Huang, Xiaojun
Publicado 2022

Correction: Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, m...

por Jiang, Qian, Li, Zongru, Qin, Yazhen, Li, Weiming, Xu, Na, Liu, Bingcheng, Zhang, Yanli, Meng, Li, Zhu, Huanling, Du, Xin, Chen, Suning, Liang, Yang, Hu, Yu, Liu, Xiaoli, Song, Yongping, Men, Lichuang, Chen, Zi, Niu, Qian, Wang, Hengbang, Lu, Ming, Yang, Dajun, Zhai, Yifan, Huang, Xiaojun
Publicado 2022

Correction: Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, m...

por Jiang, Qian, Li, Zongru, Qin, Yazhen, Li, Weiming, Xu, Na, Liu, Bingcheng, Zhang, Yanli, Meng, Li, Zhu, Huanling, Du, Xin, Chen, Suning, Liang, Yang, Hu, Yu, Liu, Xiaoli, Song, Yongping, Men, Lichuang, Chen, Zi, Niu, Qian, Wang, Hengbang, Lu, Ming, Yang, Dajun, Zhai, Yifan, Huang, Xiaojun
Publicado 2023