Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

por Du, Yi, Yamaguchi, Hirohito, Wei, Yongkun, Hsu, Jennifer L., Wang, Hung-Ling, Hsu, Yi-Hsin, Lin, Wan-Chi, Yu, Wen-Hsuan, Leonard, Paul G., Lee, Gilbert R., Chen, Mei-Kuang, Nakai, Katsuya, Hsu, Ming-Chuan, Chen, Chun-Te, Sun, Ye, Wu, Yun, Chang, Wei-Chao, Huang, Wen-Chien, Liu, Chien-Liang, Chang, Yuan-Ching, Chen, Chung-Hsuan, Park, Morag, Jones, Philip, Hortobagyi, Gabriel N., Hung, Mien-Chie
Publicado 2016

Targeting the ALK–CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex

por Chu, Yu-Yi, Chen, Mei-Kuang, Wei, Yongkun, Lee, Heng-Huan, Xia, Weiya, Wang, Ying-Nai, Yam, Clinton, Hsu, Jennifer L., Wang, Hung-Ling, Chang, Wei-Chao, Yamaguchi, Hirohito, Jiang, Zhou, Liu, Chunxiao, Li, Ching-Fei, Nie, Lei, Chan, Li-Chuan, Gao, Yuan, Wang, Shao-Chun, Liu, Jinsong, Westin, Shannon N., Lee, Sanghoon, Sood, Anil K., Yang, Liuqing, Hortobagyi, Gabriel N., Yu, Dihua, Hung, Mien-Chie
Publicado 2022