ER Stress and Apoptosis: A New Mechanism for Retinal Cell Death

por Jing, Guangjun, Wang, Joshua J., Zhang, Sarah X.
Publicado 2012

NADPH Oxidase 4-Derived H(2)O(2) Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy

por Li, Jingming, Wang, Joshua J., Zhang, Sarah X.
Publicado 2015

The unfolded protein response signaling and retinal Müller cell metabolism

por Kelly, Kristen, Wang, Joshua J., Zhang, Sarah X.
Publicado 2018

Loss of XBP1 Leads to Early-Onset Retinal Neurodegeneration in a Mouse Model of Type I Diabetes

por McLaughlin, Todd, Siddiqi, Manhal, Wang, Joshua J., Zhang, Sarah X.
Publicado 2019

Quinotrierixin inhibits proliferation of human retinal pigment epithelial cells

por Chen, Chen, Wang, Joshua J., Li, Jingming, Yu, Qiang, Zhang, Sarah X.
Publicado 2013

ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells

por Huang, Huibin, Jing, Guangjun, Wang, Joshua J, Sheibani, Nader, Zhang, Sarah X
Publicado 2015

p58(IPK) suppresses NLRP3 inflammasome activation and IL-1β production via inhibition of PKR in macrophages

por Boriushkin, Evgenii, Wang, Joshua J., Li, Junhua, Bhatta, Maulasri, Zhang, Sarah X.
Publicado 2016

Reduction of Endoplasmic Reticulum Stress Improves Angiogenic Progenitor Cell function in a Mouse Model of Type 1 Diabetes

por Bhatta, Maulasri, Chatpar, Krishna, Hu, Zihua, Wang, Joshua J., Zhang, Sarah X.
Publicado 2018

Inhibition of Reactive Oxygen Species by Lovastatin Downregulates Vascular Endothelial Growth Factor Expression and Ameliorates Blood-Retinal Barrier Breakdown in db/db Mice: Role...

por Li, Jingming, Wang, Joshua J., Yu, Qiang, Chen, Kai, Mahadev, Kalyankar, Zhang, Sarah X.
Publicado 2010

Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Müller Cell–Derived Inflammatory Cytokine Production in Diabetes

por Zhong, Yimin, Li, Jingming, Chen, Yanming, Wang, Joshua J., Ratan, Rajiv, Zhang, Sarah X.
Publicado 2012

Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications

por McLaughlin, Todd, Medina, Andy, Perkins, Jacob, Yera, Maria, Wang, Joshua J., Zhang, Sarah X.
Publicado 2022

The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions

por Ma, Jacey H., Wang, Joshua J., Li, Junhua, Pfeffer, Bruce A., Zhong, Yiming, Zhang, Sarah X.
Publicado 2016

Regulation of Nrf2 by X Box-Binding Protein 1 in Retinal Pigment Epithelium

por Chen, Chen, Zhong, Yimin, Wang, Joshua J., Yu, Qiang, Plafker, Kendra, Plafker, Scott, Zhang, Sarah X.
Publicado 2018

Macrophage Metalloelastase (MMP-12) Deficiency Mitigates Retinal Inflammation and Pathological Angiogenesis in Ischemic Retinopathy

por Li, Jingming, Wang, Joshua J., Peng, Qisheng, Chen, Chen, Humphrey, Mary Beth, Heinecke, Jay, Zhang, Sarah X.
Publicado 2012

Proteomic Analysis of Retinal Mitochondria-Associated ER Membranes Identified Novel Proteins of Retinal Degeneration in Long-Term Diabetes

por Wang, Joshua J., Park, Karen Sophia, Dhimal, Narayan, Shen, Shichen, Tang, Xixiang, Qu, Jun, Zhang, Sarah X.
Publicado 2022

Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration

por McLaughlin, Todd, Falkowski, Marek, Park, Jae Whan, Keegan, Stephen, Elliott, Michael, Wang, Joshua J., Zhang, Sarah X.
Publicado 2018

Emerging roles of circular RNAs in retinal diseases

por Hanineva, Aneliya, Park, Karen Sophia, Wang, Joshua J., DeAngelis, Margaret M., Farkas, Michael H., Zhang, Sarah X.
Publicado 2022

Neuronal p58(IPK) Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension

por McLaughlin, Todd, Wang, Jinli, Jia, Liyun, Wu, Fuguo, Wang, Yaqin, Wang, Joshua J., Mu, Xiuqian, Zhang, Sarah X.
Publicado 2023

Comparative Proteomic Analysis of the Mitochondria-associated ER Membrane (MAM) in a Long-term Type 2 Diabetic Rodent Model

por Ma, Jacey Hongjie, Shen, Shichen, Wang, Joshua J., He, Zhanwen, Poon, Amanda, Li, Jun, Qu, Jun, Zhang, Sarah X.
Publicado 2017

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

por McLaughlin, Todd, Wang, Grant, Medina, Andy, Perkins, Jacob, Nihlawi, Rhudwan, Seyfried, Don, Hu, Zihua, Wang, Joshua J., Zhang, Sarah X.
Publicado 2023