Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road

por Wang, Liang-Chuan S, Riese, Matthew J, Moon, Edmund K, Albelda, Steven M
Publicado 2013

CD11b+Ly6G+ cells inhibit tumor growth by suppressing IL-17 production at early stages of tumorigenesis

por Liu, Yuhong, O'Leary, Claire E., Wang, Liang-Chuan S., Bhatti, Tricia R., Dai, Ning, Kapoor, Veena, Liu, Peihui, Mei, Junjie, Guo, Lei, Oliver, Paula M., Albelda, Steven M., Worthen, G. Scott
Publicado 2015

Inhibition of p300 impairs Foxp3(+) T-regulatory cell function and promotes anti-tumor immunity

por Liu, Yujie, Wang, Liqing, Predina, Jarrod, Han, Rongxiang, Beier, Ulf H., Wang, Liang-Chuan S., Kapoor, Veena, Bhatti, Tricia R., Akimova, Tatiana, Singhal, Sunil, Brindle, Paul K., Cole, Philip A., Albelda, Steven M., Hancock, Wayne W.
Publicado 2013

Pharmacological inactivation of PI3Kδ in the tumor microenvironment enhances efficacy of other immunotherapeutic agents

por Wang, Liang-Chuan S, Koblish, Holly, Hansbury, Michael, Zhang, Yue, Yang, Gengjie, Burn, Timothy, Waeltz, Paul, Rupar, Mark, Yue, Eddy, Douty, Brent, Maduskuie, Thomas, Falahatpisheh, Nikoo, Li, Yun-Long, Combs, Andrew P, Hollis, Gregory, Huber, Reid, Scherle, Peggy
Publicado 2015

Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor

por Koblish, Holly K., Wu, Liangxing, Wang, Liang-Chuan S., Liu, Phillip C.C., Wynn, Richard, Rios-Doria, Jonathan, Spitz, Susan, Liu, Hao, Volgina, Alla, Zolotarjova, Nina, Kapilashrami, Kanishk, Behshad, Elham, Covington, Maryanne, Yang, Yan-ou, Li, Jingwei, Diamond, Sharon, Soloviev, Maxim, O'Hayer, Kevin, Rubin, Stephen, Kanellopoulou, Chrysi, Yang, Gengjie, Rupar, Mark, DiMatteo, Darlise, Lin, Luping, Stevens, Christina, Zhang, Yue, Thekkat, Pramod, Geschwindt, Ryan, Marando, Cindy, Yeleswaram, Swamy, Jackson, Jeff, Scherle, Peggy, Huber, Reid, Yao, Wenqing, Hollis, Gregory
Publicado 2022

A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade

por Geuijen, Cecile, Tacken, Paul, Wang, Liang-Chuan, Klooster, Rinse, van Loo, Pieter Fokko, Zhou, Jing, Mondal, Arpita, Liu, Yao-bin, Kramer, Arjen, Condamine, Thomas, Volgina, Alla, Hendriks, Linda J. A., van der Maaden, Hans, Rovers, Eric, Engels, Steef, Fransen, Floris, den Blanken-Smit, Renate, Zondag-van der Zande, Vanessa, Basmeleh, Abdul, Bartelink, Willem, Kulkarni, Ashwini, Marissen, Wilfred, Huang, Cheng-Yen, Hall, Leslie, Harvey, Shane, Kim, Soyeon, Martinez, Marina, O’Brien, Shaun, Moon, Edmund, Albelda, Steven, Kanellopoulou, Chrysi, Stewart, Shaun, Nastri, Horacio, Bakker, Alexander B. H., Scherle, Peggy, Logtenberg, Ton, Hollis, Gregory, de Kruif, John, Huber, Reid, Mayes, Patrick A., Throsby, Mark
Publicado 2021