Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

por Doyle, Laura M., Wang, Michael Zhuo
Publicado 2019

Development of a UPLC-MRM-based targeted proteomic method to profile subcellular organelle marker proteins from human liver tissues

por Qiu, Xiazi, Doyle, Laura M., Wang, Michael Zhuo
Publicado 2022

Cytochrome P450 and Flavin-containing Monooxygenase Families: Age-Dependent Differences in Expression and Functional Activity

por Zane, Nicole R., Chen, Yao, Wang, Michael Zhuo, Thakker, Dhiren R.
Publicado 2017

Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform

por Zhao, Junxing, Tang, Zhichao, Selvaraju, Manikandan, Johnson, Kristen A., Douglas, Justin T., Gao, Philip F., Petrassi, H. Michael, Wang, Michael Zhuo, Wang, Jingxin
Publicado 2022

Sterol profiling of Leishmania parasites using a new HPLC-tandem mass spectrometry-based method and antifungal azoles as chemical probes reveals a key intermediate sterol that supp...

por Feng, Mei, Jin, Yiru, Yang, Sihyung, Joachim, Arline M., Ning, Yu, Mori-Quiroz, Luis M., Fromm, Jacob, Perera, Chamani, Zhang, Kai, Werbovetz, Karl A., Wang, Michael Zhuo
Publicado 2022

Antileishmanial Activity of a Series of N(2),N(4)-Disubstituted Quinazoline-2,4-diamines

por Van Horn, Kurt S., Zhu, Xiaohua, Pandharkar, Trupti, Yang, Sihyung, Vesely, Brian, Vanaerschot, Manu, Dujardin, Jean-Claude, Rijal, Suman, Kyle, Dennis E., Wang, Michael Zhuo, Werbovetz, Karl A., Manetsch, Roman
Publicado 2014

CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles

por Jin, Yiru, Basu, Somrita, Feng, Mei, Ning, Yu, Munasinghe, Indeewara, Joachim, Arline M., Li, Junan, Madden, Robert, Burks, Hannah, Gao, Philip, Perera, Chamani, Werbovetz, Karl A., Zhang, Kai, Wang, Michael Zhuo
Publicado 2023

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

por Zhu, Xiaohua, Farahat, Abdelbasset A., Mattamana, Meena, Joice, April, Pandharkar, Trupti, Holt, Elizabeth, Banerjee, Moloy, Gragg, Jamie L., Hu, Laixing, Kumar, Arvind, Yang, Sihyung, Wang, Michael Zhuo, Boykin, David W., Werbovetz, Karl A.
Publicado 2016

The inward rectifier current inhibitor PA‐6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models

por Ji, Yuan, Varkevisser, Rosanne, Opacic, Dragan, Bossu, Alexandre, Kuiper, Marion, Beekman, Jet D M, Yang, Sihyung, Khan, Azinwi Phina, Dobrev, Dobromir, Voigt, Niels, Wang, Michael Zhuo, Verheule, Sander, Vos, Marc A, van der Heyden, Marcel A G
Publicado 2017

Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis

por Thuita, John K., Wolf, Kristina K., Murilla, Grace A., Liu, Qiang, Mutuku, James N., Chen, Yao, Bridges, Arlene S., Mdachi, Raymond E., Ismail, Mohamed A., Ching, Shelley, Boykin, David W., Hall, James Edwin, Tidwell, Richard R., Paine, Mary F., Brun, Reto, Wang, Michael Zhuo
Publicado 2013

Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates

por Padilla, Angel M., Wang, Wei, Akama, Tsutomu, Carter, David S., Easom, Eric, Freund, Yvonne, Halladay, Jason S., Liu, Yang, Hamer, Sarah A., Hodo, Carolyn L., Wilkerson, Gregory K., Orr, Dylan, White, Brooke, George, Arlene, Shen, Huifeng, Jin, Yiru, Wang, Michael Zhuo, Tse, Susanna, Jacobs, Robert T., Tarleton, Rick L.
Publicado 2022