Autistic disorder associated with a paternally derived unbalanced translocation leading to duplication of chromosome 15pter-q13.2: a case report

por Wu, David J, Wang, Nicholas J, Driscoll, Jennette, Dorrani, Naghmeh, Liu, Dahai, Sigman, Marian, Schanen, N Carolyn
Publicado 2009

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

por Hafner, Marc, Heiser, Laura M., Williams, Elizabeth H., Niepel, Mario, Wang, Nicholas J., Korkola, James E., Gray, Joe W., Sorger, Peter K.
Publicado 2017

Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15

por Wang, Nicholas J, Parokonny, Alexander S, Thatcher, Karen N, Driscoll, Jennette, Malone, Barbara M, Dorrani, Naghmeh, Sigman, Marian, LaSalle, Janine M, Schanen, N Carolyn
Publicado 2008

Patient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours

por Fei, Suzanne S., Mitchell, Asia D., Heskett, Michael B., Vocke, Cathy D., Ricketts, Christopher J., Peto, Myron, Wang, Nicholas J., Sönmez, Kemal, Linehan, W. Marston, Spellman, Paul T.
Publicado 2016

Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease

por Butler, Timothy M., Johnson-Camacho, Katherine, Peto, Myron, Wang, Nicholas J., Macey, Tara A., Korkola, James E., Koppie, Theresa M., Corless, Christopher L., Gray, Joe W., Spellman, Paul T.
Publicado 2015

Analysis of molecular inversion probe performance for allele copy number determination

por Wang, Yuker, Moorhead, Martin, Karlin-Neumann, George, Wang, Nicholas J, Ireland, James, Lin, Steven, Chen, Chunnuan, Heiser, Laura M, Chin, Koei, Esserman, Laura, Gray, Joe W, Spellman, Paul T, Faham, Malek
Publicado 2007

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

por King, Carly J., Woodward, Josha, Schwartzman, Jacob, Coleman, Daniel J., Lisac, Robert, Wang, Nicholas J., Van Hook, Kathryn, Gao, Lina, Urrutia, Joshua, Dane, Mark A., Heiser, Laura M., Alumkal, Joshi J.
Publicado 2017

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

por Heiser, Laura M, Wang, Nicholas J, Talcott, Carolyn L, Laderoute, Keith R, Knapp, Merrill, Guan, Yinghui, Hu, Zhi, Ziyad, Safiyyah, Weber, Barbara L, Laquerre, Sylvie, Jackson, Jeffrey R, Wooster, Richard F, Kuo, Wen Lin, Gray, Joe W, Spellman, Paul T
Publicado 2009

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

por Daemen, Anneleen, Wolf, Denise M., Korkola, James E., Griffith, Obi L., Frankum, Jessica R., Brough, Rachel, Jakkula, Lakshmi R., Wang, Nicholas J., Natrajan, Rachael, Reis-Filho, Jorge S., Lord, Christopher J., Ashworth, Alan, Spellman, Paul T., Gray, Joe W., van’t Veer, Laura J.
Publicado 2012

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

por Kuo, Wen-Lin, Das, Debopriya, Ziyad, Safiyyah, Bhattacharya, Sanchita, Gibb, William J, Heiser, Laura M, Sadanandam, Anguraj, Fontenay, Gerald V, Hu, Zhi, Wang, Nicholas J, Bayani, Nora, Feiler, Heidi S, Neve, Richard M, Wyrobek, Andrew J, Spellman, Paul T, Marton, Laurence J, Gray, Joe W
Publicado 2009

Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor

por Coleman, Daniel J., Van Hook, Kathryn, King, Carly J., Schwartzman, Jacob, Lisac, Robert, Urrutia, Joshua, Sehrawat, Archana, Woodward, Josha, Wang, Nicholas J., Gulati, Roman, Thomas, George V., Beer, Tomasz M., Gleave, Martin, Korkola, James E., Gao, Lina, Heiser, Laura M., Alumkal, Joshi J.
Publicado 2016

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

por Korkola, James E., Collisson, Eric A., Heiser, Laura, Oates, Chris, Bayani, Nora, Itani, Sleiman, Esch, Amanda, Thompson, Wallace, Griffith, Obi L., Wang, Nicholas J., Kuo, Wen-Lin, Cooper, Brian, Billig, Jessica, Ziyad, Safiyyah, Hung, Jenny L., Jakkula, Lakshmi, Feiler, Heidi, Lu, Yiling, Mills, Gordon B., Spellman, Paul T., Tomlin, Claire, Mukherjee, Sach, Gray, Joe W.
Publicado 2015

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

por Korkola, James E., Collisson, Eric A., Heiser, Laura M., Oates, Chris, Bayani, Nora, Itani, Sleiman, Esch, Amanda, Thompson, Wallace, Griffith, Obi L., Wang, Nicholas J., Kuo, Wen-Lin, Cooper, Brian, Billig, Jessica, Ziyad, Safiyyah, Hung, Jenny L., Jakkula, Lakshmi, Feiler, Heidi, Lu, Yiling, Mills, Gordon B., Spellman, Paul T., Tomlin, Claire, Mukherjee, Sach, Gray, Joe W.
Publicado 2017

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

por Risom, Tyler, Langer, Ellen M., Chapman, Margaret P., Rantala, Juha, Fields, Andrew J., Boniface, Christopher, Alvarez, Mariano J., Kendsersky, Nicholas D., Pelz, Carl R., Johnson-Camacho, Katherine, Dobrolecki, Lacey E., Chin, Koei, Aswani, Anil J., Wang, Nicholas J., Califano, Andrea, Lewis, Michael T., Tomlin, Claire J., Spellman, Paul T., Adey, Andrew, Gray, Joe W., Sears, Rosalie C.
Publicado 2018

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

por Shain, A. Hunter, Garrido, Maria, Botton, Thomas, Talevich, Eric, Yeh, Iwei, Sanborn, J. Zachary, Chung, Jongsuk, Wang, Nicholas J., Kakavand, Hojabr, Mann, Graham J., Thompson, John F., Wiesner, Thomas, Roy, Ritu, Olshen, Adam B., Gagnon, Alexander, Gray, Joe W., Huh, Nam, Hur, Joe S., Busam, Klaus J., Scolyer, Richard A., Cho, Raymond J., Murali, Rajmohan, Bastian, Boris C.
Publicado 2015

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

por Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., A. Dane, Mark, Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, W. Wood, Kenneth, Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Publicado 2016

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

por Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., Dane, Mark A., Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, Wood, Kenneth W., Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Publicado 2017

Modeling precision treatment of breast cancer

por Daemen, Anneleen, Griffith, Obi L, Heiser, Laura M, Wang, Nicholas J, Enache, Oana M, Sanborn, Zachary, Pepin, Francois, Durinck, Steffen, Korkola, James E, Griffith, Malachi, Hur, Joe S, Huh, Nam, Chung, Jongsuk, Cope, Leslie, Fackler, Mary Jo, Umbricht, Christopher, Sukumar, Saraswati, Seth, Pankaj, Sukhatme, Vikas P, Jakkula, Lakshmi R, Lu, Yiling, Mills, Gordon B, Cho, Raymond J, Collisson, Eric A, van’t Veer, Laura J, Spellman, Paul T, Gray, Joe W
Publicado 2013

Erratum to: Modeling precision treatment of breast cancer

por Daemen, Anneleen, Griffith, Obi L, Heiser, Laura M, Wang, Nicholas J, Enache, Oana M, Sanborn, Zachary, Pepin, Francois, Durinck, Steffen, Korkola, James E, Griffith, Malachi, Hur, Joe S, Huh, Nam, Chung, Jongsuk, Cope, Leslie, Fackler, Mary Jo, Umbricht, Christopher, Sukumar, Saraswati, Seth, Pankaj, Sukhatme, Vikas P, Jakkula, Lakshmi R, Lu, Yiling, Mills, Gordon B, Cho, Raymond J, Collisson, Eric A, van’t Veer, Laura J, Spellman, Paul T, Gray, Joe W
Publicado 2015

Timing chromosomal abnormalities using mutation data

por Durinck, Steffen, Ho, Christine, Wang, Nicholas J, Liao, Wilson, Jakkula, Lakshmi R, Collisson, Eric A, Pons, Jennifer, Chan, Sai-Wing, Lam, Ernest T, Chu, Catherine, Park, Kyunghee, Hong, Sung-woo, Hur, Joe S, Huh, Nam, Neuhaus, Isaac M, Yu, Siegrid S, Grekin, Roy C, Mauro, Theodora M, Cleaver, James E, Kwok, Pui-Yan, LeBoit, Philip E, Getz, Gad, Cibulskis, Kristian, Aster, Jon C, Huang, Haiyan, Purdom, Elizabeth, Li, Jian, Bolund, Lars, Arron, Sarah T, Gray, Joe W, Spellman, Paul T, Cho, Raymond J
Publicado 2011