Attenuating innate immunity and facilitating β-coronavirus infection by NSP1 of SARS-CoV-2 through specific redistributing hnRNP A2/B1 cellular localization

por Zhou, Fanghang, Wan, Qianya, Chen, Sheng, Chen, Ying, Wang, Pui-Hui, Yao, Xi, He, Ming-liang
Publicado 2021

Cellular 5′-3′ mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication

por Liu, Yen-Chin, Mok, Bobo Wing-Yee, Wang, Pui, Kuo, Rei-Lin, Chen, Honglin, Shih, Shin-Ru
Publicado 2021

Multiplexed detection of SARS-CoV-2 based on upconversion luminescence nanoprobe/MXene biosensing platform for COVID-19 point-of-care diagnostics

por Song, Menglin, Ma, Yingjing, Li, Lihua, Wong, Man-Chung, Wang, Pui, Chen, Jiangkun, Chen, Honglin, Wang, Feng, Hao, Jianhua
Publicado 2022

Multiple basic amino acids in the cleavage site of H7N9 hemagglutinin contribute to high virulence in mice

por Song, Wenjun, Huang, Xiaofeng, Guan, Wenda, Chen, Pin, Wang, Pui, Zheng, Min, Li, Zhengtu, Wang, Yutao, Yang, Zifeng, Chen, Honglin, Wang, Xinhua
Publicado 2021

Rapid point-of-care detection of SARS-CoV-2 RNA with smartphone-based upconversion luminescence diagnostics

por Song, Menglin, Wong, Man-Chung, Li, Lihua, Guo, Feng, Liu, Yuan, Ma, Yingjing, Lao, Xinyue, Wang, Pui, Chen, Honglin, Yang, Mo, Hao, Jianhua
Publicado 2023

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans

por Wang, Pui, Song, Wenjun, Mok, Bobo Wing-Yee, Zheng, Min, Lau, Siu-Ying, Liu, Siwen, Chen, Pin, Huang, Xiaofeng, Liu, Honglian, Cremin, Conor J., Chen, Honglin
Publicado 2019

An A14U Substitution in the 3′ Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M S...

por Zheng, Min, Wang, Pui, Song, Wenjun, Lau, Siu-Ying, Liu, Siwen, Huang, Xiaofeng, Mok, Bobo Wing-Yee, Liu, Yen-Chin, Chen, Yixin, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2015

The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication

por Song, Wenjun, Wang, Pui, Mok, Bobo Wing-Yee, Lau, Siu-Ying, Huang, Xiaofeng, Wu, Wai-Lan, Zheng, Min, Wen, Xi, Yang, Shigui, Chen, Yu, Li, Lanjuan, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2014

An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells

por Huang, Xiaofeng, Zheng, Min, Wang, Pui, Mok, Bobo Wing-Yee, Liu, Siwen, Lau, Siu-Ying, Chen, Pin, Liu, Yen-Chin, Liu, Honglian, Chen, Yixin, Song, Wenjun, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2017

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

por Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Li, Can, Chen, Yanxia, Liu, Feifei, Zhao, Yan, Chu, Hin, Fong, Carol Ho-Yan, Wang, Pui, Lau, Siu-Ying, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Publicado 2021

A CRISPR-Cas12a integrated SERS nanoplatform with chimeric DNA/RNA hairpin guide for ultrasensitive nucleic acid detection

por Yin, Bohan, Zhang, Qin, Xia, Xinyue, Li, Chuanqi, Ho, Willis Kwun Hei, Yan, Jiaxiang, Huang, Yingying, Wu, Honglian, Wang, Pui, Yi, Changqing, Hao, Jianhua, Wang, Jianfang, Chen, Honglin, Wong, Siu Hong Dexter, Yang, Mo
Publicado 2022

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

por Lau, Siu-Ying, Wang, Pui, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Chu, Hin, Lee, Andrew Chak-Yiu, Deng, Shaofeng, Chen, Pin, Chan, Kwok-Hung, Song, Wenjun, Chen, Zhiwei, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2020

An intranasal influenza virus-vectored vaccine prevents SARS-CoV-2 replication in respiratory tissues of mice and hamsters

por Deng, Shaofeng, Liu, Ying, Tam, Rachel Chun-Yee, Chen, Pin, Zhang, Anna Jinxia, Mok, Bobo Wing-Yee, Long, Teng, Kukic, Anja, Zhou, Runhong, Xu, Haoran, Song, Wenjun, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Zhiwei, Yuen, Kwok-Yung, Wang, Pui, Chen, Honglin
Publicado 2023

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

por Wang, Pui, Zheng, Min, Lau, Siu-Ying, Chen, Pin, Mok, Bobo Wing-Yee, Liu, Siwen, Liu, Honglian, Huang, Xiaofeng, Cremin, Conor J., Song, Wenjun, Chen, Yixin, Wong, Yik-Chun, Huang, Haode, To, Kelvin Kai-Wong, Chen, Zhiwei, Xia, Ningshao, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2019

Identification of influenza A nucleoprotein as an antiviral target

por Kao, Richard Y, Yang, Dan, Lau, Lai-Shan, Tsui, Wayne H W, Hu, Lihong, Dai, Jun, Chan, Mei-Po, Chan, Che-Man, Wang, Pui, Zheng, Bo-Jian, Sun, Jian, Huang, Jian-Dong, Madar, Jason, Chen, Guanhua, Chen, Honglin, Guan, Yi, Yuen, Kwok-Yung
Publicado 2010

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

por Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Publicado 2020

Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals

por Ye, Zi-Wei, Ong, Chon Phin, Tang, Kaiming, Fan, Yilan, Luo, Cuiting, Zhou, Runhong, Luo, Peng, Cheng, Yun, Gray, Victor Sebastien, Wang, Pui, Chu, Hin, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Honglin, Chen, Zhiwei, Yuen, Kwok-Yung, Ling, Guang Sheng, Yuan, Shuofeng, Jin, Dong-Yan
Publicado 2022

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

por Wang, Pui, Lau, Siu-Ying, Deng, Shaofeng, Chen, Pin, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Kwok-Hung, Tam, Rachel Chun-Yee, Xu, Haoran, Zhou, Runhong, Song, Wenjun, Liu, Li, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chen, Zhiwei, Yuen, Kwok-Yung, Chen, Honglin
Publicado 2021

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

por Mok, Bobo Wing-Yee, Liu, Honglian, Deng, Shaofeng, Liu, Jiayan, Zhang, Anna Jinxia, Lau, Siu-Ying, Liu, Siwen, Tam, Rachel Chun-Yee, Cremin, Conor J., Ng, Timothy Ting-Leung, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Wang, Pui, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chan, Kwok-Hung, Yuen, Kwok-Yung, Siu, Gilman Kit-Hang, Chen, Honglin
Publicado 2021

Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models

por Zhou, Runhong, Wang, Pui, Wong, Yik-Chun, Xu, Haoran, Lau, Siu-Ying, Liu, Li, Mok, Bobo Wing-Yee, Peng, Qiaoli, Liu, Na, Woo, Kin-Fai, Deng, Shaofeng, Tam, Rachel Chun-Yee, Huang, Haode, Zhang, Anna Jinxia, Zhou, Dongyan, Zhou, Biao, Chan, Chun-Yin, Du, Zhenglong, Yang, Dawei, Au, Ka-Kit, Yuen, Kwok-Yung, Chen, Honglin, Chen, Zhiwei
Publicado 2021