The correlation between Th17/Treg immune dysregulation and the disease severity in chronic spontaneous urticaria patients

por Yang, Xiaojing, Chen, Leigang, Wang, Shining, Wu, Yuanhui, Zhou, Xiangzhao, Meng, Zhaoying
Publicado 2023

Safety, tolerability, pharmacokinetics, pharmacodynamics, bioavailability and food effect of single doses of soticlestat in healthy subjects

por Wang, Shining, Chen, Grace, Merlo Pich, Emilio, Affinito, John, Cwik, Michael, Faessel, Hélène
Publicado 2021

Combination of modified carbapenem inactivation method (mCIM) and EDTA-CIM (eCIM) for phenotypic detection of carbapenemase-producing Enterobacteriaceae

por Tsai, Ya-Min, Wang, Shining, Chiu, Hui-Chuan, Kao, Cheng-Yen, Wen, Li-Li
Publicado 2020

Pharmacokinetics, pharmacodynamics and safety assessment of multiple doses of soticlestat in healthy volunteers

por Wang, Shining, Chen, Grace, Merlo Pich, Emilio, Affinito, John, Cwik, Michael, Faessel, Hélène M.
Publicado 2022

Clinical Characterization of [(18)F]T-008, a Cholesterol 24-Hydroxylase PET Ligand: Dosimetry, Kinetic Modeling, Variability, and Soticlestat Occupancy

por Constantinescu, Cristian C., Brown, Terry, Wang, Shining, Yin, Wei, Barret, Olivier, Jennings, Danna, Tauscher, Johannes
Publicado 2023

The Role of Aldose Reductase in Beta-Amyloid-Induced Microglia Activation

por Huang, Yu-Kai, Liu, Chia-Chun, Wang, Shining, Cheng, Hui-Chun, Meadows, Chandler, Chang, Kun-Che
Publicado 2022

Population pharmacokinetic and exposure‐response analyses from ALTA‐1L: Model‐based analyses supporting the brigatinib dose in ALK‐positive NSCLC

por Gupta, Neeraj, Reckamp, Karen L., Camidge, David R., Kleijn, Huub J., Ouerdani, Aziz, Bellanti, Francesco, Maringwa, John, Hanley, Michael J., Wang, Shining, Zhang, Pingkuan, Venkatakrishnan, Karthik
Publicado 2022

A phase I, first-in-human study of TAK-164, an antibody–drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C

por Kim, Richard, Leal, Alexis D., Parikh, Aparna, Ryan, David P., Wang, Shining, Bahamon, Brittany, Gupta, Neeraj, Moss, Aaron, Pye, Joanna, Miao, Harry, Inguilizian, Haig, Cleary, James M.
Publicado 2023

Correction to: A phase I, first-in-human study of TAK-164, an antibody–drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C

por Kim, Richard, Leal, Alexis D., Parikh, Aparna, Ryan, David P., Wang, Shining, Bahamon, Brittany, Gupta, Neeraj, Moss, Aaron, Pye, Joanna, Miao, Harry, Inguilizian, Haig, Cleary, James M.
Publicado 2023

PB2129: THE MODAKAFUSP ALFA IINNOVATE CLINICAL DEVELOPMENT PROGRAM: RATIONALE AND DESIGN OF 3 PHASE 1/2 TRIALS OF AN INNATE IMMUNITY ENHANCER FOR MULTIPLE MYELOMA (MM)

por Holstein, Sarah A., Mian, Hira, Touzeau, Cyrille, Kingsley, Edwin, Vogl, Dan, Zuniga, Richard, Suryanarayan, Kaveri, Wang, Shining, Thesillat-Versmee, Laura, Liu, Yuyin, Chen, Tian, Zhang, Yefei, Parot, Xavier, Lee, Hans C.
Publicado 2023

Distinct Characteristics of Escherichia coli Isolated from Patients with Urinary Tract Infections in a Medical Center at a Ten-Year Interval

por Lin, Wei-Hung, Zhang, Yen-Zhen, Liu, Po-Yao, Chen, Po-Shun, Wang, Shining, Kuo, Pei-Yun, Thuy, Tran Thi Dieu, Duong, Tran Thi Thuy, Wen, Li-Li, Hsieh, Yi-Hsien, Wang, Ming-Cheng, Kao, Cheng-Yen
Publicado 2021

A Longitudinal Nine-Year Study of the Molecular Epidemiology of Carbapenemase-Producing Enterobacterales Isolated From a Regional Hospital in Taiwan: Predominance of Carbapenemase...

por Duong, Tran Thi Thuy, Tsai, Ya-Min, Wen, Li-Li, Chiu, Hui-Chuan, Chen, Pek Kee, Thuy, Tran Thi Dieu, Kuo, Pei-Yun, Hidrosollo, Jazon Harl, Wang, Shining, Zhang, Yen-Zhen, Lin, Wei-Hung, Wang, Ming-Cheng, Kao, Cheng-Yen
Publicado 2022

A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia

por Pratz, Keith W., Kaplan, Jason, Levy, Moshe, Bixby, Dale, Burke, Patrick W., Erba, Harry, Wise-Draper, Trisha M., Roboz, Gail J., Papadantonakis, Nikolaos, Rajkhowa, Trivikram, Hernandez, Daniela, Dobler, Iwona, Gregory, Richard C., Li, Cheryl, Wang, Shining, Stumpo, Kate, Kannan, Karuppiah, Miao, Harry, Levis, Mark
Publicado 2022

Spleen tyrosine kinase/FMS-like tyrosine kinase-3 inhibition in relapsed/refractory B-cell lymphoma, including diffuse large B-cell lymphoma: updated data with mivavotinib (TAK-659...

por Gordon, Leo I., Karmali, Reem, Kaplan, Jason B., Popat, Rakesh, Burris, Howard A., Ferrari, Silvia, Madan, Sumit, Patel, Manish R., Gritti, Giuseppe, El-Sharkawi, Dima, Chau, F. Ian, Radford, John, de Oteyza, Jaime Pérez, Zinzani, Pier Luigi, Iyer, Swaminathan P., Townsend, William, Miao, Harry, Proscurshim, Igor, Wang, Shining, Katyayan, Shilpi, Yuan, Ying, Zhu, Jiaxi, Stumpo, Kate, Shou, Yaping, Carpio, Cecilia, Bosch, Francesc
Publicado 2023