Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

por Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.
Publicado 2018

Safety risk management for low molecular weight process‐related impurities in monoclonal antibody therapeutics: Categorization, risk assessment, testing strategy, and process devel...

por Luo, Haibin, Li, Yuling, Robbins, David, Wang, Sheau‐Chiann, Xi, Guoling, Cox, Matthew, Nicholson, Simone M., Wei, Chenghong, Pabst, Timothy M., Wang, William K.
Publicado 2021

Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

por Linke, Thomas, Aspelund, Matthew T, Thompson, Christopher, Xi, Guoling, Fulton, Andrew, Wendeler, Michaela, Pabst, Timothy M, Wang, Xiangyang, Wang, William K, Ram, Kripa, Hunter, Alan K
Publicado 2014