Identifying Structural Features of Nucleotide Analogues to Overcome SARS-CoV-2 Exonuclease Activity

por Wang, Xuanting, Tao, Chuanjuan, Morozova, Irina, Kalachikov, Sergey, Li, Xiaoxu, Kumar, Shiv, Russo, James J., Ju, Jingyue
Publicado 2022

Commercially Available Flavonols Are Better SARS-CoV-2 Inhibitors than Isoflavone and Flavones

por Chaves, Otávio Augusto, Fintelman-Rodrigues, Natalia, Wang, Xuanting, Sacramento, Carolina Q., Temerozo, Jairo R., Ferreira, André C., Mattos, Mayara, Pereira-Dutra, Filipe, Bozza, Patrícia T., Castro-Faria-Neto, Hugo Caire, Russo, James J., Ju, Jingyue, Souza, Thiago Moreno L.
Publicado 2022

Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics

por Wang, Xuanting, Sacramento, Carolina Q., Jockusch, Steffen, Chaves, Otávio Augusto, Tao, Chuanjuan, Fintelman-Rodrigues, Natalia, Chien, Minchen, Temerozo, Jairo R., Li, Xiaoxu, Kumar, Shiv, Xie, Wei, Patel, Dinshaw J., Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas, Bozza, Patrícia T., Russo, James J., Souza, Thiago Moreno L., Ju, Jingyue
Publicado 2021

Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture

por Wang, Xuanting, Sacramento, Carolina Q., Jockusch, Steffen, Chaves, Otávio Augusto, Tao, Chuanjuan, Fintelman-Rodrigues, Natalia, Chien, Minchen, Temerozo, Jairo R., Li, Xiaoxu, Kumar, Shiv, Xie, Wei, Patel, Dinshaw J., Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas, Bozza, Patrícia T., Russo, James J., Souza, Thiago Moreno L., Ju, Jingyue
Publicado 2022

Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells

por Nguyenla, Xammy, Wehri, Eddie, Van Dis, Erik, Biering, Scott B., Yamashiro, Livia H., Zhu, Chi, Stroumza, Julien, Dugast-Darzacq, Claire, Graham, Thomas G. W., Wang, Xuanting, Jockusch, Steffen, Tao, Chuanjuan, Chien, Minchen, Xie, Wei, Patel, Dinshaw J., Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas, Russo, James J., Ju, Jingyue, Näär, Anders M., Stanley, Sarah, Schaletzky, Julia
Publicado 2022