Conquering oncogenic KRAS and its bypass mechanisms

por Hou, Pingping, Wang, Y. Alan
Publicado 2022

Abraxane-induced bone marrow CD11b(+) myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with (64)Cu-labeled anti-CD11b and prevented by anti-CSF-1

por Cao, Qizhen, Huang, Qian, Wang, Y. Alan, Li, Chun
Publicado 2021

Localization of Putative Stem Cells in Dental Epithelium and Their Association with Notch and Fgf Signaling

por Harada, Hidemitsu, Kettunen, Päivi, Jung, Han-Sung, Mustonen, Tuija, Wang, Y. Alan, Thesleff, Irma
Publicado 1999

Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association

por Wu, Chia-Chin, Wang, Y. Alan, Livingston, J. Andrew, Zhang, Jianhua, Futreal, P. Andrew
Publicado 2022

Effects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer Cells

por Sun, Yuan, Li, Ying-xia, Wu, Hai-jun, Wu, Si-hung, Wang, Y. Alan, Luo, Dian-zhong, Liao, D. Joshua
Publicado 2011

LKB1 regulates quiescence and metabolic homeostasis of hematopoietic stem cells

por Gan, Boyi, Hu, Jian, Jiang, Shan, Liu, Yingchun, Sahin, Ergün, Zhuang, Li, Fletcher-Sananikone, Eliot, Colla, Simona, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado 2010

Opposing roles of TGFβ and BMP signaling in prostate cancer development

por Lu, Xin, Jin, Eun-Jung, Cheng, Xi, Feng, Shan, Shang, Xiaoying, Deng, Pingna, Jiang, Shan, Chang, Qing, Rahmy, Sharif, Chaudhary, Seema, Lu, Xuemin, Zhao, Ren, Wang, Y. Alan, DePinho, Ronald A.
Publicado 2017

Effective Combinatorial Immunotherapy for Castration Resistant Prostate Cancer

por Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.
Publicado 2017

USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation

por Hou, Pingping, Ma, Xingdi, Zhang, Qiang, Wu, Chang-Jiun, Liao, Wenting, Li, Jun, Wang, Huamin, Zhao, Jun, Zhou, Xin, Guan, Carolyn, Ackroyd, Jeffery, Jiang, Shan, Zhang, Jianhua, Spring, Denise J., Wang, Y. Alan, DePinho, Ronald A.
Publicado 2019

USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer

por Shi, Dongni, Wu, Xianqiu, Jian, Yunting, Wang, Junye, Huang, Chengmei, Mo, Shuang, Li, Yue, Li, Fengtian, Zhang, Chao, Zhang, Dongsheng, Zhang, Huizhong, Huang, Huilin, Chen, Xin, Wang, Y. Alan, Lin, Chuyong, Liu, Guozhen, Song, Libing, Liao, Wenting
Publicado 2022

USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer

por Hou, Pingping, Ma, Xingdi, Yang, Zecheng, Zhang, Qiang, Wu, Chang-Jiun, Li, Jun, Tan, Lin, Yao, Wantong, Yan, Liang, Zhou, Xin, Kimmelman, Alec C., Lorenzi, Philip L., Zhang, Jianhua, Jiang, Shan, Spring, Denise, Wang, Y. Alan, DePinho, Ronald A.
Publicado 2021

Oncogenic Kras drives invasion and maintains metastases in colorectal cancer

por Boutin, Adam T., Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V., Cheung, Hannah, Chu, Gerald C., Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y. Alan, Kwong, Lawrence N., DePinho, Ronald A.
Publicado 2017

Passenger Deletions Generate Therapeutic Vulnerabilities in Cancer

por Muller, Florian L., Colla, Simona, Aquilanti, Elisa, Manzo, Veronica, Genovese, Giannicola, Lee, Jaclyn, Eisenson, Dan, Narurkar, Rujuta, Deng, Pingna, Nezi, Luigi, Lee, Michelle, Hu, Baoli, Hu, Jian, Sahin, Ergun, Ong, Derrick, Fletcher-Sananikone, Eliot, Ho, Dennis, Kwong, Lawrence, Brennan, Cameron, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado 2012

SF2312 is a natural phosphonate inhibitor of Enolase

por Leonard, Paul G., Satani, Nikunj, Maxwell, David, Lin, Yu-Hsi, Hammoudi, Naima, Peng, Zhenghong, Pisaneschi, Federica, Link, Todd M., Lee, Gilbert R., Sun, Duoli, Prasad, Basvoju A. Bhanu, Di Francesco, Maria Emilia, Czako, Barbara, Asara, John M., Wang, Y. Alan, Bornmann, William, DePinho, Ronald A., Muller, Florian L.
Publicado 2016

Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer

por Dayde, Delphine, Gunther, Jillian, Hirayama, Yutaka, Weksberg, David C., Boutin, Adam, Parhy, Gargy, Aguilar-Bonavides, Clemente, Wang, Hong, Katayama, Hiroyuki, Abe, Yuichi, Do, Kim-Anh, Hara, Kazuo, Kinoshita, Takashi, Komori, Koji, Shimizu, Yasuhiro, Tajika, Masahiro, Niwa, Yasumasa, Wang, Y. Alan, DePinho, Ronald, Hanash, Samir, Krishnan, Sunil, Taguchi, Ayumu
Publicado 2021

P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

por Zheng, Hongwu, Ying, Haoqiang, Yan, Haiyan, Kimmelman, Alec C., Hiller, David J., Chen, An-Jou, Perry, Samuel R., Tonon, Giovanni, Chu, Gerald C., Ding, Zhihu, Stommel, Jayne M., Dunn, Katherine L., Wiedemeyer, Ruprecht, You, Mingjian J., Brennan, Cameron, Wang, Y. Alan, Ligon, Keith L., Wong, Wing H., Chin, Lynda, DePinho, Ronald A.
Publicado 2008

Targeting YAP-dependent MDSC infiltration impairs tumor progression

por Wang, Guocan, Lu, Xin, Dey, Prasenjit, Deng, Pingna, Wu, Chia Chin, Jiang, Shan, Fang, Zhuangna, Zhao, Kun, Konaparthi, Ramakrishna, Hua, Sujun, Zhang, Jianhua, Li Ning Tapia, Elsa M, Kapoor, Avnish, Patel, Neelay, Guo, Zhenglin, Ramamoorthy, Vandhana, Tieu, Trang, Heffernan, Tim, Zhao, Di, Shang, Xiaoying, Khadka, Sunada, Hou, Pingping, Hu, Baoli, Chang, Qing, Troncoso, Patricia, Logothetis, Christopher, McArthur, Mark, Chin, Lynda, Wang, Y Alan, DePinho, Ronald
Publicado 2015

Telomere dysfunction activates YAP1 to drive tissue inflammation

por Chakravarti, Deepavali, Hu, Baoli, Mao, Xizeng, Rashid, Asif, Li, Jiexi, Li, Jun, Liao, Wen-ting, Whitley, Elizabeth M., Dey, Prasenjit, Hou, Pingping, LaBella, Kyle A., Chang, Andrew, Wang, Guocan, Spring, Denise J., Deng, Pingna, Zhao, Di, Liang, Xin, Lan, Zhengdao, Lin, Yiyun, Sarkar, Sharmistha, Terranova, Christopher, Deribe, Yonathan Lissanu, Blutt, Sarah E., Okhuysen, Pablo, Zhang, Jianhua, Vilar, Eduardo, Nielsen, Ole Haagen, Dupont, Andrew, Younes, Mamoun, Patel, Kalyani R., Shroyer, Noah F., Rai, Kunal, Estes, Mary K., Wang, Y. Alan, Bertuch, Alison A., DePinho, Ronald A.
Publicado 2020