Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy

por Roszik, Jason, Ring, Kari L., Wani, Khalida M., Lazar, Alexander J., Yemelyanova, Anna V., Soliman, Pamela T., Frumovitz, Michael, Jazaeri, Amir A.
Publicado 2018

A gene expression signature predicts recurrence-free survival in meningioma

por Olar, Adriana, Goodman, Lindsey D., Wani, Khalida M., Boehling, Nicholas S., Sharma, Devi S., Mody, Reema R., Gumin, Joy, Claus, Elizabeth B., Lang, Frederick F., Cloughesy, Timothy F., Lai, Albert, Aldape, Kenneth D., DeMonte, Franco, Sulman, Erik P.
Publicado 2018

Biphasic components of sarcomatoid clear cell renal cell carcinomas are molecularly similar to each other, but distinct from, non‐sarcomatoid renal carcinomas

por Sircar, Kanishka, Yoo, Suk‐Young, Majewski, Tadeusz, Wani, Khalida, Patel, Lalit R., Voicu, Horatiu, Torres‐Garcia, Wandaliz, Verhaak, Roel G. W., Tannir, Nizar, Karam, Jose A., Jonasch, Eric, Wood, Christopher G., Tamboli, Pheroze, Baggerly, Keith A., Aldape, Kenneth D., Czerniak, Bogdan
Publicado 2015

Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy

por Qin, Yong, Bollin, Kathryn, de Macedo, Mariana Petaccia, Carapeto, Fernando, Kim, Kevin B, Roszik, Jason, Wani, Khalida M, Reuben, Alexandre, Reddy, Sujan T, Williams, Michelle D, Tetzlaff, Michael T, Wang, Wei-Lien, Gombos, Dan S, Esmaeli, Bita, Lazar, Alexander J, Hwu, Patrick, Patel, Sapna P
Publicado 2020

Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma

por Beird, Hannah C., Wu, Chia-Chin, Nakazawa, Michael, Ingram, Davis, Daniele, Joseph R., Lazcano, Rossana, Little, Latasha, Davies, Christopher, Daw, Najat C., Wani, Khalida, Wang, Wei-Lien, Song, Xingzhi, Gumbs, Curtis, Zhang, Jianhua, Rubin, Brian, Conley, Anthony, Flanagan, Adrienne M., Lazar, Alexander J., Futreal, P. Andrew
Publicado 2023

Intratumoral Morphologic and Molecular Heterogeneity of Rhabdoid Renal Cell Carcinoma: Challenges for Personalized Therapy

por Singh, Rajesh R., Murugan, Paari, Patel, Lalit R., Voicu, Horatiu, Yoo, Suk-Young, Majewski, Tadeusz, Mehrotra, Meenakshi, Wani, Khalida, Tannir, Nizar, Karam, Jose A., Jonasch, Eric, Wood, Christopher G., Creighton, Chad J., Medeiros, L. Jeffrey, Broaddus, Russell R., Tamboli, Pheroze, Baggerly, Keith A., Aldape, Kenneth D., Czerniak, Bogdan, Luthra, Rajyalakshmi, Sircar, Kanishka
Publicado 2015

Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker

por Fischer, Grant M., Carapeto, Fernando C. L., Joon, Aron Y., Haydu, Lauren E., Chen, Huiqin, Wang, Fuchenchu, Van Arnam, John S., McQuade, Jennifer L., Wani, Khalida, Kirkwood, John M., Thompson, John F., Tetzlaff, Michael T., Lazar, Alexander J., Tawbi, Hussein A., Gershenwald, Jeffrey E., Scolyer, Richard A., Long, Georgina V., Davies, Michael A.
Publicado 2020

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

por Terranova, Christopher J., Tang, Ming, Maitituoheti, Mayinuer, Raman, Ayush T., Ghosh, Archit K., Schulz, Jonathan, Amin, Samir B., Orouji, Elias, Tomczak, Katarzyna, Sarkar, Sharmistha, Oba, Junna, Creasy, Caitlin, Wu, Chang-Jiun, Khan, Samia, Lazcano, Rossana, Wani, Khalida, Singh, Anand, Barrodia, Praveen, Zhao, Dongyu, Chen, Kaifu, Haydu, Lauren E., Wang, Wei-Lien, Lazar, Alexander J., Woodman, Scott E., Bernatchez, Chantale, Rai, Kunal
Publicado 2021

Identification of MicroRNA–mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes

por Sloane, Robert A. Szczepaniak, White, Michael G., Witt, Russell G., Banerjee, Anik, Davies, Michael A., Han, Guangchun, Burton, Elizabeth, Ajami, Nadim, Simon, Julie M., Bernatchez, Chantale, Haydu, Lauren E., Tawbi, Hussein A., Gershenwald, Jeffrey E., Keung, Emily, Ross, Merrick, McQuade, Jennifer, Amaria, Rodabe N., Wani, Khalida, Lazar, Alexander J., Woodman, Scott E., Wang, Linghua, Andrews, Miles C., Wargo, Jennifer A.
Publicado 2021

Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma

por White, Michael G., Szczepaniak Sloane, Robert, Witt, Russell G., Reuben, Alexandre, Gaudreau, Pierre Olivier, Andrews, Miles C., Feng, Ningping, Johnson, Sarah, Class, Caleb A., Bristow, Christopher, Wani, Khalida, Hudgens, Courtney, Nezi, Luigi, Manzo, Teresa, De Macedo, Mariana Pettaccia, Hu, Jianhua, Davis, Richard, Jiang, Hong, Prieto, Peter, Burton, Elizabeth, Hwu, Patrick, Tawbi, Hussein, Gershenwald, Jeffrey, Lazar, Alexander J., Tetzlaff, Michael T., Overwijk, Willem, Woodman, Scott E, Cooper, Zachary A., Marszalek, Joseph R., Davies, Michael A., Heffernan, Timothy P., Wargo, Jennifer A.
Publicado 2021

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

por Mitra, Akash, Andrews, Miles C., Roh, Whijae, De Macedo, Marianna Petaccia, Hudgens, Courtney W., Carapeto, Fernando, Singh, Shailbala, Reuben, Alexandre, Wang, Feng, Mao, Xizeng, Song, Xingzhi, Wani, Khalida, Tippen, Samantha, Ng, Kwok-Shing, Schalck, Aislyn, Sakellariou-Thompson, Donald A., Chen, Eveline, Reddy, Sangeetha M., Spencer, Christine N., Wiesnoski, Diana, Little, Latasha D., Gumbs, Curtis, Cooper, Zachary A., Burton, Elizabeth M., Hwu, Patrick, Davies, Michael A., Zhang, Jianhua, Bernatchez, Chantale, Navin, Nicholas, Sharma, Padmanee, Allison, James P., Wargo, Jennifer A., Yee, Cassian, Tetzlaff, Michael T., Hwu, Wen-Jen, Lazar, Alexander J., Futreal, P. Andrew
Publicado 2020

Multi-modal molecular programs regulate melanoma cell state

por Andrews, Miles C., Oba, Junna, Wu, Chang-Jiun, Zhu, Haifeng, Karpinets, Tatiana, Creasy, Caitlin A., Forget, Marie-Andrée, Yu, Xiaoxing, Song, Xingzhi, Mao, Xizeng, Robertson, A. Gordon, Romano, Gabriele, Li, Peng, Burton, Elizabeth M., Lu, Yiling, Sloane, Robert Szczepaniak, Wani, Khalida M., Rai, Kunal, Lazar, Alexander J., Haydu, Lauren E., Bustos, Matias A., Shen, Jianjun, Chen, Yueping, Morgan, Margaret B., Wargo, Jennifer A., Kwong, Lawrence N., Haymaker, Cara L., Grimm, Elizabeth A., Hwu, Patrick, Hoon, Dave S. B., Zhang, Jianhua, Gershenwald, Jeffrey E., Davies, Michael A., Futreal, P. Andrew, Bernatchez, Chantale, Woodman, Scott E.
Publicado 2022

The immune landscape of undifferentiated pleomorphic sarcoma

por Lazcano, Rossana, Barreto, Carmelia M., Salazar, Ruth, Carapeto, Fernando, Traweek, Raymond S., Leung, Cheuk H., Gite, Swati, Mehta, Jay, Ingram, Davis R., Wani, Khalida M., Vu, Kim-Anh T., Parra, Edwin R., Lu, Wei, Zhou, Jianling, Witt, Russell G., Cope, Brandon, Thirasastr, Prapassorn, Lin, Heather Y., Scally, Christopher P., Conley, Anthony P., Ratan, Ravin, Livingston, J. Andrew, Zarzour, Alexandra M., Ludwig, Joseph, Araujo, Dejka, Ravi, Vinod, Patel, Shreyaskumar, Benjamin, Robert, Wargo, Jennifer, Wistuba, Ignacio I., Somaiah, Neeta, Roland, Christina L., Keung, Emily Z., Solis, Luisa, Wang, Wei-Lien, Lazar, Alexander J., Nassif, Elise F.
Publicado 2022

Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

por Zhou, Yifan, Medik, Yusra B., Patel, Bhakti, Zamler, Daniel B., Chen, Sijie, Chapman, Thomas, Schneider, Sarah, Park, Elizabeth M., Babcock, Rachel L., Chrisikos, Taylor T., Kahn, Laura M., Dyevoich, Allison M., Pineda, Josue E., Wong, Matthew C., Mishra, Aditya K., Cass, Samuel H., Cogdill, Alexandria P., Johnson, Daniel H., Johnson, Sarah B., Wani, Khalida, Ledesma, Debora A., Hudgens, Courtney W., Wang, Jingjing, Wadud Khan, Md Abdul, Peterson, Christine B., Joon, Aron Y., Peng, Weiyi, Li, Haiyan S., Arora, Reetakshi, Tang, Ximing, Raso, Maria Gabriela, Zhang, Xuegong, Foo, Wai Chin, Tetzlaff, Michael T., Diehl, Gretchen E., Clise-Dwyer, Karen, Whitley, Elizabeth M., Gubin, Matthew M., Allison, James P., Hwu, Patrick, Ajami, Nadim J., Diab, Adi, Wargo, Jennifer A., Watowich, Stephanie S.
Publicado 2022

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

por Reuben, Alexandre, Spencer, Christine N., Prieto, Peter A., Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Miller, John P., Mao, Xizeng, De Macedo, Mariana Petaccia, Chen, Jiong, Song, Xingzhi, Jiang, Hong, Chen, Pei-Ling, Beird, Hannah C., Garber, Haven R., Roh, Whijae, Wani, Khalida, Chen, Eveline, Haymaker, Cara, Forget, Marie-Andrée, Little, Latasha D., Gumbs, Curtis, Thornton, Rebecca L., Hudgens, Courtney W., Chen, Wei-Shen, Austin-Breneman, Jacob, Sloane, Robert Szczepaniak, Nezi, Luigi, Cogdill, Alexandria P., Bernatchez, Chantale, Roszik, Jason, Hwu, Patrick, Woodman, Scott E., Chin, Lynda, Tawbi, Hussein, Davies, Michael A., Gershenwald, Jeffrey E., Amaria, Rodabe N., Glitza, Isabella C., Diab, Adi, Patel, Sapna P., Hu, Jianhua, Lee, Jeffrey E., Grimm, Elizabeth A., Tetzlaff, Michael T., Lazar, Alexander J., Wistuba, Ignacio I., Clise-Dwyer, Karen, Carter, Brett W., Zhang, Jianhua, Futreal, P. Andrew, Sharma, Padmanee, Allison, James P., Cooper, Zachary A., Wargo, Jennifer A.
Publicado 2017

DNA methylation-based classification of central nervous system tumours

por Capper, David, Jones, David T.W., Sill, Martin, Hovestadt, Volker, Schrimpf, Daniel, Sturm, Dominik, Koelsche, Christian, Sahm, Felix, Chavez, Lukas, Reuss, David E., Kratz, Annekathrin, Wefers, Annika K., Huang, Kristin, Pajtler, Kristian W., Schweizer, Leonille, Stichel, Damian, Olar, Adriana, Engel, Nils W., Lindenberg, Kerstin, Harter, Patrick N., Braczynski, Anne, Plate, Karl H., Dohmen, Hildegard, Garvalov, Boyan K., Coras, Roland, Hölsken, Annett, Hewer, Ekkehard, Bewerunge-Hudler, Melanie, Schick, Matthias, Fischer, Roger, Beschorner, Rudi, Schittenhelm, Jens, Staszewski, Ori, Wani, Khalida, Varlet, Pascale, Pages, Melanie, Temming, Petra, Lohmann, Dietmar, Selt, Florian, Witt, Hendrik, Milde, Till, Witt, Olaf, Aronica, Eleonora, Giangaspero, Felice, Rushing, Elisabeth, Scheurlen, Wolfram, Geisenberger, Christoph, Rodriguez, Fausto J., Becker, Albert, Preusser, Matthias, Haberler, Christine, Bjerkvig, Rolf, Cryan, Jane, Farrell, Michael, Deckert, Martina, Hench, Jürgen, Frank, Stephan, Serrano, Jonathan, Kannan, Kasthuri, Tsirigos, Aristotelis, Brück, Wolfgang, Hofer, Silvia, Brehmer, Stefanie, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Hans, Volkmar, Rozsnoki, Stephanie, Hansford, Jordan R., Kohlhof, Patricia, Kristensen, Bjarne W., Lechner, Matt, Lopes, Beatriz, Mawrin, Christian, Ketter, Ralf, Kulozik, Andreas, Khatib, Ziad, Heppner, Frank, Koch, Arend, Jouvet, Anne, Keohane, Catherine, Mühleisen, Helmut, Mueller, Wolf, Pohl, Ute, Prinz, Marco, Benner, Axel, Zapatka, Marc, Gottardo, Nicholas G., Driever, Pablo Hernáiz, Kramm, Christof M., Müller, Hermann L., Rutkowski, Stefan, von Hoff, Katja, Frühwald, Michael C., Gnekow, Astrid, Fleischhack, Gudrun, Tippelt, Stephan, Calaminus, Gabriele, Monoranu, Camelia-Maria, Perry, Arie, Jones, Chris, Jacques, Thomas S., Radlwimmer, Bernhard, Gessi, Marco, Pietsch, Torsten, Schramm, Johannes, Schackert, Gabriele, Westphal, Manfred, Reifenberger, Guido, Wesseling, Pieter, Weller, Michael, Collins, Vincent Peter, Blümcke, Ingmar, Bendszus, Martin, Debus, Jürgen, Huang, Annie, Jabado, Nada, Northcott, Paul A., Paulus, Werner, Gajjar, Amar, Robinson, Giles, Taylor, Michael D., Jaunmuktane, Zane, Ryzhova, Marina, Platten, Michael, Unterberg, Andreas, Wick, Wolfgang, Karajannis, Matthias A., Mittelbronn, Michel, Acker, Till, Hartmann, Christian, Aldape, Kenneth, Schüller, Ulrich, Buslei, Rolf, Lichter, Peter, Kool, Marcel, Herold-Mende, Christel, Ellison, David W., Hasselblatt, Martin, Snuderl, Matija, Brandner, Sebastian, Korshunov, Andrey, von Deimling, Andreas, Pfister, Stefan M.
Publicado 2018